{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:59:49Z","timestamp":1791583189702,"version":"4.3.4"},"reference-count":39,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,21]],"date-time":"2023-01-21T00:00:00Z","timestamp":1674259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Background: Ghana ranked 31st worldwide and 3rd in Africa in the number of confirmed cases worldwide. We aimed to assess the intention to receive the monkeypox (MPOX) vaccine and its associated psychological antecedents among the Ghanaian population. Methods: A cross-sectional online survey was conducted in Ghana from November to December 2022. Snowball sampling was used to recruit participants via social media platforms, such as WhatsApp, LinkedIn, Telegram, and Facebook. The validated 5C scale was used to assess five psychological factors that influence vaccination behavior and intent: confidence, complacency, constraints, calculation, and collective responsibility. Results: The study drew 605 participants; their mean age was 30.0 \u00b1 6.8; 68.1% were single; 60.8 % were males, and 51.9% were living in Greater Accra (The capital and largest city of Ghana). About 53.9% of the studied Ghanaian population did not intend to receive the MPOX vaccination. Vaccine acceptance among non-healthcare workers (non-HCWs) was significantly lower than among HCWs (41.7 vs. 55.3, p &lt; 0.001). The determinants of vaccine acceptance were male gender (AOR = 1.48, 95% CI, 1.00\u20132.18, p = 0.049), urban residence (AOR = 0.63, 95% CI, 0.41\u20130.96, p = 0.033), refusal of coronavirus 2019 vaccine (AOR = 0.29, 95% CI, 0.16\u20130.52, p &lt; 0.001), confidence in vaccination ((AOR = 2.45, 95% CI, 1.93\u20133.15, and p &lt; 0.001), and collective responsibility (AOR = 1.34, 95% CI, 1.02\u20131.75, p = 0.034)). Conclusions: The participants in this study did not show high levels of intention to accept the MPOX vaccination. Consequently, tailoring the efforts aiming to promote MPOX vaccination is needed especially among non-HCWs through increasing their confidence in vaccine effectiveness and safety and promoting the importance of self-vaccination to protect others.<\/jats:p>","DOI":"10.3390\/vaccines11020240","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T03:21:54Z","timestamp":1674616914000},"page":"240","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Monkeypox Vaccine Acceptance among Ghanaians: A Call for Action"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7611-706X","authenticated-orcid":false,"given":"Ramy Mohamed","family":"Ghazy","sequence":"first","affiliation":[{"name":"Tropical Health Department, High Institute of Public Health, Alexandria University, Alexandria 21561, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1612-8709","authenticated-orcid":false,"given":"Saja","family":"Yazbek","sequence":"additional","affiliation":[{"name":"Faculty of Public Health, Lebanese University, Beirut 6573, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assem","family":"Gebreal","sequence":"additional","affiliation":[{"name":"Alexandria Faculty of Medicine, Alexandria University, Alexandria 21568, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Hussein","sequence":"additional","affiliation":[{"name":"Clinical Research Administration, Alexandria Directorate of Health Affairs, Alexandria 21554, Egypt"},{"name":"Ministry of Health and Population, Cairo 71529, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia Agyeman","family":"Addai","sequence":"additional","affiliation":[{"name":"Department of Science & Department of Educational Administration and Management, University of Education, Winneba CE-119-9961, Ghana"},{"name":"Business School, Datalink University, Tema GN-03-266605, Ghana"},{"name":"Human Resource & Marketing Department, Central University, Miotso-Prampram GT-001-5571, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernestina","family":"Mensah","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Seventh Day Adventist Nursing and Midwifery Training College, Agona-Asamang P.O. Box GN 37, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7380-1608","authenticated-orcid":false,"given":"Michael","family":"Sarfo","sequence":"additional","affiliation":[{"name":"School of Human and Health Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agyapong","family":"Kofi","sequence":"additional","affiliation":[{"name":"Manhyia Government Hospital, Kumasi AK-039-5028, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6693-4525","authenticated-orcid":false,"given":"Tareq","family":"AL-Ahdal","sequence":"additional","affiliation":[{"name":"Institute of Global Health (HIGH), Heidelberg University, Neuenheimer Feld 130\/3, 69120 Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9836-0834","authenticated-orcid":false,"given":"Gilbert","family":"Eshun","sequence":"additional","affiliation":[{"name":"Seventh Day Adventist Hospital, Agona-Asamang AZ-0581-8540, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Harapan, H., Ophinni, Y., Megawati, D., Frediansyah, A., Mamada, S.S., Salampe, M., Bin Emran, T., Winardi, W., Fathima, R., and Sirinam, S. 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