{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T20:40:03Z","timestamp":1775853603559,"version":"3.50.1"},"reference-count":26,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>We report a 78-year-old man presenting with persistent headaches in vertex and temporo-parietal area; fatigue, worsening after walking; jaw claudication; scotomas; pharyngodynia; and dry cough after the second dose of the SARS-CoV-2 vaccine (ChAdOx1-S) administration. Laboratory findings showed an elevated C-reactive protein level and FDG-CT PET showed evidence of active large vessel vasculitis with diffuse abnormal artery uptake. Under suspicion of vasculitis, a temporal arteries biopsy was performed; the histopathologic findings demonstrated the transmural inflammatory infiltrate with giant cells, compatible with giant cell arteritis. Although the overall incidence of vaccine-triggered autoimmunity is low, rheumatologists worldwide should be aware of autoimmune diseases as a new potential adverse event of vaccines.<\/jats:p>","DOI":"10.3390\/vaccines11020434","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T02:41:56Z","timestamp":1676342516000},"page":"434","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["New Onset of Giant Cell Arteritis following ChAdOx1-S (Vaxevria\u00ae) Vaccine Administration"],"prefix":"10.3390","volume":"11","author":[{"given":"Luca","family":"Lo Sardo","sequence":"first","affiliation":[{"name":"Unit of Rheumatology, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"},{"name":"Clinical Immunology and Allergy Unit, AO Ordine Mauriziano, 10128 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Parisi","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Chiara","family":"Ditto","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"De Giovanni","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Maletta","sequence":"additional","affiliation":[{"name":"Pathology Unit, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serena","family":"Grimaldi","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7249-7616","authenticated-orcid":false,"given":"Luisa","family":"Brussino","sequence":"additional","affiliation":[{"name":"Clinical Immunology and Allergy Unit, AO Ordine Mauriziano, 10128 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Fusaro","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, \u201cAOU Citt\u00e0 della Salute e della Scienza\u201d Hospital, 10126 Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/art.41924","article-title":"Disease Flare and Reactogenicity in Patients With Rheumatic and Musculoskeletal Diseases Following Two-Dose SARS\u2013CoV-2 Messenger RNA Vaccination","volume":"74","author":"Connolly","year":"2021","journal-title":"Arthritis Rheumatol."},{"key":"ref_2","first-page":"1","article-title":"First description of immune complex vasculitis after COVID-19 vaccination with BNT162b2: A case report","volume":"21","author":"Knop","year":"2021","journal-title":"BMC Infect. 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