{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T04:09:24Z","timestamp":1773720564938,"version":"3.50.1"},"reference-count":19,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T00:00:00Z","timestamp":1689897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Tetanus toxoid (TT) vaccination during pregnancy has been proven as an effective preventative measure to reduce the incidence of maternal and neonatal morbidity and mortality worldwide. This study aimed to assess the determinants of TT vaccine uptake among pregnant women at two public maternity specialized hospitals in Sudan. A hospital-based cross-sectional study was conducted at two public hospitals, Omdurman Maternity Hospital and Al Saudi Hospital in Omdurman, Khartoum State, in Sudan from February to April 2020. Logistic regression analysis was carried out to identify factors associated with receiving three or more doses of the TT vaccine among pregnant women, presented as odds ratios, with p-values &lt; 0.05 considered significant (at a 95% confidence interval). The study recruited 350 pregnant women, with 313 participants included in the analysis. This study found that only 40% of the pregnant women had received three doses or more of the TT vaccine. Pregnant women who attended Al Saudi Hospital were less likely to be vaccinated with the recommended dose of the TT vaccine in districts at high risk (received \u22653 doses) compared to those who attended Omdurman Hospital [OR = 0.49 (95% C.I. 0.29\u20130.82), p-value &lt; 0.05]. Furthermore, the number of children at home was a significant predictor of the mothers\u2019 immunization status as those with five children or more were ten times more likely to be vaccinated with three doses or more [OR = 10.54 (95% C.I. 4.30\u201325.86), p-value &lt; 0.05]. We conclude that this low rate of TT vaccine uptake found in this study among pregnant women increases the number of newborn babies susceptible to contracting neonatal tetanus. The findings of this study should be considered in the development of communication strategies targeting and prioritizing at-risk groups to increase TT vaccine uptake among pregnant women in Sudan.<\/jats:p>","DOI":"10.3390\/vaccines11071268","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T00:57:30Z","timestamp":1690160250000},"page":"1268","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Predictors of Tetanus Vaccine Uptake among Pregnant Women in Khartoum State, Sudan: A Hospital-Based Cross-Sectional Study"],"prefix":"10.3390","volume":"11","author":[{"given":"Zienab A.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Federal Ministry of Health, Khartoum P.O. Box 303, Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6095-2172","authenticated-orcid":false,"given":"Majdi M.","family":"Sabahelzain","sequence":"additional","affiliation":[{"name":"Nutrition and Health Center for Training and Research, Ahfad University for Women, Omdurman P.O. Box 167, Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3649-0374","authenticated-orcid":false,"given":"Yasir Ahmed Mohammed","family":"Elhadi","sequence":"additional","affiliation":[{"name":"Public Health Department, Sudanese Medical Research Association, Khartoum P.O. Box 303, Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1840-7402","authenticated-orcid":false,"given":"Ombeva Oliver","family":"Malande","sequence":"additional","affiliation":[{"name":"Department of Child Health and Paediatrics, Egerton University, Nakuru P.O. Box 3366-20100, Kenya"},{"name":"East Africa Centre for Vaccines and Immunization (ECAVI), Namela House, Kampala P.O. Box 3040, Uganda"},{"name":"Department of Paediatrics & Child Health, Makerere University, Kampala P.O. Box 3040, Uganda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suad","family":"Babiker","sequence":"additional","affiliation":[{"name":"School of Medicine, Ahfad University for Women, Omdurman P.O. Box 167, Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ijid.2023.04.402","article-title":"Global epidemiology and burden of tetanus from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"132","author":"Li","year":"2023","journal-title":"Int. J. Infect. 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