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This cohort study included all singleton live births at our center from March 1 to June 30, 2022. According to whether a maternal inactivated COVID-19 vaccination had been administered within 3 months before conception or not, neonates were identified as being in the vaccinated or unvaccinated group. Vaccination information and clinical characteristics were extracted for analysis. Furthermore, neonatal outcomes were analyzed and compared between these two groups in the present study. The cohort included 856 eligible newborns, of whom 369 were exposed to maternal vaccination before conception and 487 were unexposed newborns. No differences were observed in rates of preterm birth, newborns being small for gestational age, or neonatal intensive care unit admission between exposed and unexposed newborns. Furthermore, even after adjusting for social\u2013economic status and maternal characteristics, there remained no significant differences in these neonatal outcomes. Our study revealed no statistically significant differences between newborns born to women who received inactivated vaccines prior to conception compared with those who did not receive any vaccinations. In addition, our study also highlights the importance of considering COVID-19 vaccination before conception.<\/jats:p>","DOI":"10.3390\/vaccines11111710","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:10:43Z","timestamp":1699841443000},"page":"1710","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of Maternal Inactivated COVID-19 Vaccination within 3 Months before Conception with Neonatal Outcomes"],"prefix":"10.3390","volume":"11","author":[{"given":"Zhihui","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingbo","family":"Mu","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Center for Reproductive Medicine, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lulu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ge","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2206-6548","authenticated-orcid":false,"given":"Fangrui","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China"},{"name":"Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin 300199, China"},{"name":"Department of Neonatology, Nankai University Maternity Hospital, Tianjin 300052, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2023, July 30). 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