{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:16:00Z","timestamp":1760145360440,"version":"build-2065373602"},"reference-count":38,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Patients with axial spondyloarthritis (axSpA) who receive immunosuppressive therapy are at risk of infection due to impaired immune function and immunosuppressive medication. Vaccination plays a crucial role in preventing infections in this population. However, vaccination rates and factors influencing vaccination uptake in axSpA patients still need to be adequately studied. This study was designed to determine the vaccination rates of vaccines covered by health insurance in this particular group in Turkey and attitudes towards vaccines and infections. This survey included 199 patients with axSpA who visited our outpatient clinic in June, July, and August 2023 and received biologic and targeted synthetic disease-modifying antirheumatic drugs. The mean age of the participants was 43.7 \u00b1 0.7 years, and the majority were male (66.3%). The majority of the patients were vaccinated against COVID-19 (85.4%), followed by hepatitis B (41.2%), influenza (20.1%), and pneumococcal pneumonia (10.5%). While awareness of COVID-19 vaccination was widespread (100%), knowledge of other vaccines was lower (hepatitis B 80.9%, influenza 70.3%, pneumococcal 60.3%, respectively). Educational interventions targeting patients and healthcare professionals are needed to improve vaccination rates in this population. Our findings emphasize the need for strategies to increase vaccination rates in axSpA patients receiving immunosuppressive therapy. Removing barriers to vaccination and raising awareness of the importance of vaccination are critical to optimizing vaccination practices in this vulnerable population.<\/jats:p>","DOI":"10.3390\/vaccines12070756","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T15:27:20Z","timestamp":1720538840000},"page":"756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vaccination Rates and Influencing Factors in Patients with Axial Spondyloarthritis and Immunosuppressive Treatment\u2014A Survey-Based Cross-Sectional Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4560-1569","authenticated-orcid":false,"given":"Tu\u011fba","family":"Ocak","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selin","family":"\u0130ldemir Ekizo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burcu","family":"Ya\u011f\u0131z","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0298-4157","authenticated-orcid":false,"given":"Belk\u0131s Nihan","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ediz","family":"Dalk\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1201-8836","authenticated-orcid":false,"given":"Yavuz","family":"Pehlivan","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Uludag University, Nil\u00fcfer 16285, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0140-6736(16)31591-4","article-title":"Axial spondyloarthritis","volume":"390","author":"Sieper","year":"2017","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1002\/art.41042","article-title":"2019 update of the American College of Rheumatology\/Spondylitis Association of America\/Spondyloarthritis Research and Treatment Network recommendations for the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis","volume":"71","author":"Ward","year":"2019","journal-title":"Arthritis Rheumatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1136\/annrheumdis-2018-213590","article-title":"Impact of biological therapy on work outcomes in patients with axial spondyloarthritis: Results from the British Society for Rheumatology Biologics Register (BSRBR-AS) and meta-analysis","volume":"77","author":"Shim","year":"2018","journal-title":"Ann. 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