{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:19:11Z","timestamp":1760145551711,"version":"build-2065373602"},"reference-count":51,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chongqing Science and Technology Bureau","award":["CSTC2021jscx-gksb-N0005","cstc2024ycjh-bgzxm0224"],"award-info":[{"award-number":["CSTC2021jscx-gksb-N0005","cstc2024ycjh-bgzxm0224"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Background: Influenza vaccination is essential for type 2 diabetes mellitus (T2DM) patients due to their higher risks of severe complications and mortality from influenza. This study investigated the willingness of T2DM patients in Chongqing, China, to receive the influenza vaccination during the 2023\/2024 season, using behavioral and social drivers (BeSD) tools to improve vaccination uptake in this high-risk group. Methods: A multi-stage sampling method was used to select participants, and face-to-face surveys were conducted in community health centers between March 1 and May 1, 2023. Binary logistic regression was used to analyze the factors influencing vaccination willingness, and standardized scores identified barriers and drivers. Results: Among 1672 T2DM patients, 11.7% had been vaccinated during the 2022\/2023 season, and 59.6% were willing to receive the vaccination in the 2023\/2024 season. Higher willingness was associated with ethnic minorities (odds ratio [OR], 3.18, 95% confidence interval [CI]: 1.58\u20136.39), being unemployed individuals (OR 2.69, 95% CI: 1.60\u20134.52), higher monthly household income per capita (OR 2.72, 95% CI: 1.65\u20134.50), having diabetes complications (OR 1.76, 95% CI: 1.23\u20132.51), sufficient vaccine knowledge (OR 1.87, 95% CI: 1.48\u20132.37), and previous vaccination (OR 7.75, 95% CI: 4.83\u201312.44). Concerning BeSDs, fear of infecting friends or family members and trust in vaccine efficacy were the predominant drivers, while high vaccine costs were the greatest barrier. Conclusions: Future strategies should focus on improving vaccine knowledge, supporting healthcare workers and peer recommendations, and enhancing vaccination policies. Key interventions such as health education among high-risk groups, such as unemployed individuals, advocacy campaigns, pay-it-forward strategies, and policies for free vaccination could improve coverage in Chongqing.<\/jats:p>","DOI":"10.3390\/vaccines12080898","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T15:04:24Z","timestamp":1723129464000},"page":"898","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Increasing Influenza Vaccination Rates among Patients with Type 2 Diabetes Mellitus in Chongqing, China: A Cross-Sectional Analysis Using Behavioral and Social Drivers Tools"],"prefix":"10.3390","volume":"12","author":[{"given":"Zhourong","family":"Li","sequence":"first","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400799, China"},{"name":"School of Public Health, Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luzhao","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Long","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400799, China"},{"name":"Chongqing Municipal Key Laboratory for High Pathogenic Microbes, Chongqing 400799, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Xiong","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400799, China"},{"name":"Chongqing Municipal Key Laboratory for High Pathogenic Microbes, Chongqing 400799, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8268-5132","authenticated-orcid":false,"given":"Tingting","family":"Li","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400799, China"},{"name":"Chongqing Municipal Key Laboratory for High Pathogenic Microbes, Chongqing 400799, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7077-4958","authenticated-orcid":false,"given":"Binshan","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Public Health, Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Fu","sequence":"additional","affiliation":[{"name":"School of Public Health, Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3099-3299","authenticated-orcid":false,"given":"Zumin","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9290-109X","authenticated-orcid":false,"given":"Yong","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Public Health, Chongqing Medical University, Chongqing 400016, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Qi","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400799, China"},{"name":"Chongqing Municipal Key Laboratory for High Pathogenic Microbes, Chongqing 400799, China"},{"name":"Infectious Disease Control and Prevention, Chongqing Municipal Center for Disease Control and Prevention,  Chongqing 400799, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/jdi.12785","article-title":"Prevalence, treatment patterns and control rates of metabolic syndrome in a Chinese diabetic population: China Cardiometabolic Registries 3B study","volume":"9","author":"Jing","year":"2018","journal-title":"J. Diabetes Investig."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/joim.12984","article-title":"Higher frequency of hospitalization but lower relative mortality for pandemic influenza in people with type 2 diabetes","volume":"287","author":"Ruiz","year":"2020","journal-title":"J. Intern. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5095","DOI":"10.1016\/j.vaccine.2017.07.095","article-title":"Benefits of flu vaccination for persons with diabetes mellitus: A review","volume":"35","author":"Goeijenbier","year":"2017","journal-title":"Vaccine"},{"key":"ref_4","unstructured":"World Health Organization (2024, March 08). Influenza (Seasonal). Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/influenza-(seasonal)."},{"key":"ref_5","unstructured":"National Immunization Advisory Committee (NIAC) Technical Working Group (TWG), and Influenza Vaccination TWG (2022). Technical guidelines for seasonal influenza vaccination in China (2022\u20132023). Zhonghua Liu Xing Bing Xue Za Zhi, 43, 1515\u20131544."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Bechini, A., Ninci, A., Del Riccio, M., Biondi, I., Bianchi, J., Bonanni, P., Mannucci, E., and Monami, M. (2020). Impact of Influenza Vaccination on All-Cause Mortality and Hospitalization for Pneumonia in Adults and the Elderly with Diabetes: A Meta-Analysis of Observational Studies. Vaccines, 8.","DOI":"10.3390\/vaccines8020263"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1016\/j.vaccine.2020.01.093","article-title":"Influenza vaccination rate and its association with chronic diseases in China: Results of a national cross-sectional study","volume":"38","author":"Fan","year":"2020","journal-title":"Vaccine"},{"key":"ref_8","first-page":"1560","article-title":"Investigation on influenza vaccination policy and vaccination situation during the influenza seasons of 2020\u20132021 and 2021\u20132022 in China","volume":"56","author":"Zhao","year":"2022","journal-title":"Zhonghua Yu Fang Yi Xue Za Zhi"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1016\/j.vaccine.2015.04.036","article-title":"Vaccine hesitancy: Definition, scope and determinants","volume":"33","author":"MacDonald","year":"2015","journal-title":"Vaccine"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1080\/21645515.2017.1423157","article-title":"Knowledge, Attitudes and Practices (KAP) toward seasonal influenza vaccine among young workers in South China","volume":"14","author":"Ma","year":"2018","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Dallagiacoma, G., Allora, A., Salvati, S., Cocciolo, G., Capraro, M., Lamberti, A., Senatore, S., Gentile, L., Gianfredi, V., and Laurenzi, A. (2021). Type 1 Diabetes Patients\u2019 Practice, Knowledge and Attitudes towards Influenza Immunization. Vaccines, 9.","DOI":"10.3390\/vaccines9070707"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Chen, S., Jiang, Y., Tang, X., Gan, L., Xiong, Y., Chen, T., and Peng, B. (2022). Research on Knowledge, Attitudes, and Practices of Influenza Vaccination Among Healthcare Workers in Chongqing, China-Based on Structural Equation Model. Front. Public Health, 10.","DOI":"10.3389\/fpubh.2022.853041"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Erazo, C.E., Erazo, C.V., Grijalva, M.J., and Moncayo, A.L. (2021). Knowledge, attitudes and practices on influenza vaccination during pregnancy in Quito, Ecuador. BMC Public Health, 21.","DOI":"10.1186\/s12889-020-10061-4"},{"key":"ref_14","unstructured":"World Health Organization (2022, October 05). Understanding the Behavioural and Social Drivers of Vaccine Uptake WHO Position Paper\u2013May 2022. Available online: https:\/\/www.who.int\/publications\/i\/item\/who-wer9720-209-224."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"100140","DOI":"10.1016\/j.jvacx.2021.100140","article-title":"Explaining the intention to uptake COVID-19 vaccination using the behavioral and social drivers of vaccination (BeSD) model","volume":"10","author":"Alagarsamy","year":"2022","journal-title":"Vaccine X"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Jiang, B., Cao, Y., Qian, J., Jiang, M., Huang, Q., Sun, Y., Dai, P., Yi, H., Zhang, R., and Xu, L. (2023). Healthcare Workers\u2019 Attitudes toward Influenza Vaccination: A Behaviour and Social Drivers Survey. Vaccines, 11.","DOI":"10.3390\/vaccines11010143"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1080\/21645515.2019.1693721","article-title":"Mortality burden from seasonal influenza in Chongqing, China, 2012\u20132018","volume":"16","author":"Qi","year":"2020","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_18","first-page":"78","article-title":"Analysis of prevalence, mortality and disability-adjusted life year rate of diabetes in Chongqing City","volume":"41","author":"Ding","year":"2021","journal-title":"J. Shanghai Jiao Tong Univ. (Med. Dcience)"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Welch, V.L., Metcalf, T., Macey, R., Markus, K., Sears, A.J., Enstone, A., Langer, J., Srivastava, A., Cane, A., and Wiemken, T.L. (2023). Understanding the Barriers and Attitudes toward Influenza Vaccine Uptake in the Adult General Population: A Rapid Review. Vaccines, 11.","DOI":"10.3390\/vaccines11010180"},{"key":"ref_20","unstructured":"Department of Primary Health Care, National Health Commission, PRC (2023, October 30). Standards for National Basic Public Health Services, Available online: http:\/\/www.nhc.gov.cn\/jws\/s3578\/201703\/aefef3d0b2a14279b76ad57d7e7a2c4e.shtml."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Zhou, L., Su, Q., Xu, Z., Feng, A., Jin, H., Wang, S., and Feng, Z. (2013). Seasonal influenza vaccination coverage rate of target groups in selected cities and provinces in China by season (2009\/10 to 2011\/12). PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0073724"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.vaccine.2017.01.004","article-title":"Influenza vaccination in older people with diabetes and their household contacts","volume":"35","author":"Yang","year":"2017","journal-title":"Vaccine"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1017\/S0007114514002657","article-title":"Optimal cut-off values of BMI, waist circumference and waist:height ratio for defining obesity in Chinese adults","volume":"112","author":"Zeng","year":"2014","journal-title":"Br. J. Nutr."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"4886","DOI":"10.1016\/j.vaccine.2015.07.052","article-title":"Dutch influenza vaccination rate drops for fifth consecutive year","volume":"33","author":"Tacken","year":"2015","journal-title":"Vaccine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.vaccine.2016.11.039","article-title":"Influenza vaccination in people with type 2 diabetes, coverage, predictors of uptake, and perceptions. Result of the MADIABETES cohort a 7 years follow up study","volume":"35","year":"2017","journal-title":"Vaccine"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Lee, D.-H., Yang, B., Gu, S., Kim, E.-G., Kim, Y., Kang, H.K., Choe, Y.H., Jeon, H.J., Park, S., and Lee, H. (2023). Influenza vaccination trend and related factors among patients with diabetes in Korea: Analysis using a nationwide database. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1077846"},{"key":"ref_27","unstructured":"World Health Organization (2024, March 08). Prevention and Control of Influenza Pandemics and Annual Epidemics. Available online: https:\/\/apps.who.int\/gb\/archive\/pdf_files\/WHA56\/ea56r19.pdf."},{"key":"ref_28","unstructured":"World Health Organization (2023, October 10). Influenza Vaccination Coverage and Effectiveness. Available online: https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/influenza-vaccination-coverage-and-effectiveness."},{"key":"ref_29","first-page":"905","article-title":"The analysis of knowledge-attitude-practice (KAP) and Influencing Factors of Influenza Vaccination in Type 2 Diabetes Mellitus (T2DM) Patients","volume":"26","author":"Yuan","year":"2018","journal-title":"Chin. J. Prev. Control. Chronic Dis."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Feng, W., Cui, J., and Li, H. (2019). Determinants of Willingness of Patients with Type 2 Diabetes Mellitus to Receive the Seasonal Influenza Vaccine in Southeast China. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16122203"},{"key":"ref_31","first-page":"1126","article-title":"lnfluenza vaccination intention and its influencing factors among the patients with type 2 diabetes mellitus in Changsha","volume":"32","author":"Hu","year":"2020","journal-title":"China Prev. Med. J."},{"key":"ref_32","unstructured":"Guillari, A., Polito, F., Pucciarelli, G., Serra, N., Gargiulo, G., Esposito, M.R., Botti, S., Rea, T., and Simeone, S. (2021). Influenza vaccination and healthcare workers: Barriers and predisposing factors. Acta Biomed., 92."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Li, T., Qi, X., Li, Q., Tang, W., Su, K., Jia, M., Yang, W., Xia, Y., Xiong, Y., and Qi, L. (2021). A Systematic Review and Meta-Analysis of Seasonal Influenza Vaccination of Health Workers. Vaccines, 9.","DOI":"10.3390\/vaccines9101104"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"6375","DOI":"10.1016\/j.vaccine.2017.10.006","article-title":"A cross sectional survey to evaluate knowledge, attitudes and practices regarding seasonal influenza and influenza vaccination among diabetics in Pretoria, South Africa","volume":"35","author":"Olatunbosun","year":"2017","journal-title":"Vaccine"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Alnaheelah, I.M., Awadalla, N.J., Al-Musa, K.M., Alsabaani, A.A., and Mahfouz, A.A. (2018). Influenza Vaccination in Type 2 Diabetes Patients: Coverage Status and Its Determinants in Southwestern Saudi Arabia. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15071381"},{"key":"ref_36","first-page":"1389","article-title":"Willingness of influenza vaccination among elderly residents over 65 years old in Chongqing Municipality and its influence factors analysis","volume":"50","author":"Yang","year":"2021","journal-title":"Chongqing Med. J."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Verger, P., Bocquier, A., Vergelys, C., Ward, J., and Peretti-Watel, P. (2018). Flu vaccination among patients with diabetes: Motives, perceptions, trust, and risk culture\u2014A qualitative survey. BMC Public Health, 18.","DOI":"10.1186\/s12889-018-5441-6"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"6667","DOI":"10.1016\/j.vaccine.2014.08.080","article-title":"Determinants of the public intent to receive the seasonal influenza vaccine and protective behaviors: A population-based study in Taiwan","volume":"32","author":"Tsai","year":"2014","journal-title":"Vaccine"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S2213-2600(22)00266-1","article-title":"Does repeated influenza vaccination attenuate effectiveness? A systematic review and meta-analysis","volume":"11","author":"Robinson","year":"2023","journal-title":"Lancet Resp. Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1177\/1529100618760521","article-title":"Increasing Vaccination: Putting Psychological Science Into Action","volume":"18","author":"Brewer","year":"2017","journal-title":"Psychol. Sci. Public Interestig."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Sallam, M., Ghazy, R.M., Al-Salahat, K., Al-Mahzoum, K., AlHadidi, N.M., Eid, H., Kareem, N., Al-Ajlouni, E., Batarseh, R., and Ababneh, N.A. (2022). The Role of Psychological Factors and Vaccine Conspiracy Beliefs in Influenza Vaccine Hesitancy and Uptake among Jordanian Healthcare Workers during the COVID-19 Pandemic. Vaccines, 10.","DOI":"10.3390\/vaccines10081355"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1080\/21645515.2018.1446719","article-title":"Immunogenicity, safety, and effectiveness of seasonal influenza vaccination in patients with diabetes mellitus: A systematic review","volume":"14","author":"Dos","year":"2018","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1080\/21645515.2018.1496767","article-title":"Determinants of healthcare workers\u2019 willingness to recommend the seasonal influenza vaccine to diabetic patients: A cross-sectional survey in Ningbo, China","volume":"14","author":"Ye","year":"2018","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1080\/21645515.2017.1403704","article-title":"Innovations in adult influenza vaccination in China, 2014-2015: Leveraging a chronic disease management system in a community-based intervention","volume":"14","author":"Yi","year":"2018","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Rong, H., Lai, X., Ma, X., Hou, Z., Li, S., Jing, R., Zhang, H., Peng, Z., Feng, L., and Fang, H. (2020). Seasonal Influenza Vaccination and Recommendation: The Difference between General Practitioners and Public Health Workers in China. Vaccines, 8.","DOI":"10.3390\/vaccines8020265"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Watkinson, R.E., Williams, R., Gillibrand, S., Munford, L., and Sutton, M. (2023). Evaluating socioeconomic inequalities in influenza vaccine uptake during the COVID-19 pandemic: A cohort study in Greater Manchester, England. PLoS Med., 20.","DOI":"10.1371\/journal.pmed.1004289"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1080\/21645515.2019.1709351","article-title":"Seasonal influenza vaccine uptake among Chinese in Hong Kong: Barriers, enablers and vaccination rates","volume":"16","author":"Sun","year":"2020","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S1473-3099(22)00346-2","article-title":"Effectiveness of a pay-it-forward intervention compared with user-paid vaccination to improve influenza vaccine uptake and community engagement among children and older adults in China: A quasi-experimental pragmatic trial","volume":"22","author":"Wu","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"ref_49","unstructured":"National Bureau of Statistics of China (2024, July 16). Households\u2019 Income and Consumption Expenditure in 2023, Available online: https:\/\/www.stats.gov.cn\/english\/PressRelease\/202402\/t20240201_1947120.html."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2195786","DOI":"10.1080\/21645515.2023.2195786","article-title":"Vaccine co-administration in adults: An effective way to improve vaccination coverage","volume":"19","author":"Bonanni","year":"2023","journal-title":"Hum. Vaccines Immunother."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1159\/000519469","article-title":"Associations between Combined Influenza and Pneumococcal Pneumonia Vaccination and Cardiovascular Outcomes","volume":"146","author":"Ma","year":"2021","journal-title":"Cardiology"}],"container-title":["Vaccines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-393X\/12\/8\/898\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:32:00Z","timestamp":1760110320000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-393X\/12\/8\/898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,8]]},"references-count":51,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["vaccines12080898"],"URL":"https:\/\/doi.org\/10.3390\/vaccines12080898","relation":{},"ISSN":["2076-393X"],"issn-type":[{"type":"electronic","value":"2076-393X"}],"subject":[],"published":{"date-parts":[[2024,8,8]]}}}