{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:21:38Z","timestamp":1762978898884,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:00:00Z","timestamp":1740009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Background\/Objective: This study explores the epidemiology and clinical features of re-emerging mpox in Jakarta, Indonesia. Methods: This study used a retrospective study design to describe the epidemiological data, clinical features, and mortality of mpox patients from August 2022 to December 2023. In addition, this study also aims to identify the differences in both the epidemiology and clinical features of mpox in people living with HIV (PLHIV) and in non-HIV patients (non-PLHIV). Results: Our study shows that, as of the end of December 2023, 59 mpox cases were treated in Jakarta. All of the mpox cases in Jakarta were diagnosed in males, mainly found in MSM (91.5%), and PLHIV (78%). Most patients would manifest with fever, rash, and skin lesions. Syphilis was found as a concomitant infection in this group (22\/59, 37.2%). Severe manifestations were found among PLHIV without antiretroviral therapy (ART). Conclusions: Mpox cases in Jakarta were all found in males and most of them were PLHIV. There are various manifestations of mpox; however, since immunosuppressed patients could present differently, a strong surveillance and vaccine notification system, cautious management, and spreading vaccination awareness are needed to prevent and treat mpox.<\/jats:p>","DOI":"10.3390\/vaccines13030210","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T04:53:39Z","timestamp":1740027219000},"page":"210","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiology and Clinical Features of Mpox in Jakarta, Indonesia, August 2022\u2013December 2023"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2530-7258","authenticated-orcid":false,"given":"Hanny","family":"Nilasari","sequence":"first","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Dermatology and Venereology, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliza","family":"Miranda","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Dermatology and Venereology, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melani","family":"Marissa","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Dermatology and Venereology, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ani","family":"Ruspitawati","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dwi O. T. L.","family":"Handayani","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ngabila","family":"Salama","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Budi","family":"Setiawan","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Supriadi","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiranti V.","family":"Aisyah","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Inggariwati","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arif S.","family":"Haq","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti","family":"Zuhroh","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eka Y.","family":"Safitri","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahmat A.","family":"Pramono","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inggrita","family":"Wisnuwardani","sequence":"additional","affiliation":[{"name":"DKI Jakarta Health District, Jakarta 10160, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4064-5412","authenticated-orcid":false,"given":"Erni J.","family":"Nelwan","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Internal Medicine, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Sinto","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Internal Medicine, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adityo","family":"Susilo","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Internal Medicine, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6065-0329","authenticated-orcid":false,"given":"Yulia R.","family":"Saharman","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Clinical Microbiology, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suratno L.","family":"Ratnoglik","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Clinical Microbiology, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ni L. P.","family":"Pitawati","sequence":"additional","affiliation":[{"name":"National Infectious Disease Center Sulianti Saroso Hospital, Jakarta 14340, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4175-5222","authenticated-orcid":false,"given":"Muhammad","family":"Fauzan","sequence":"additional","affiliation":[{"name":"National Infectious Disease Center Sulianti Saroso Hospital, Jakarta 14340, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5128-9177","authenticated-orcid":false,"given":"Sekar S. A.","family":"Hasanah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Trisakti University, Jakarta 11440, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8032-4116","authenticated-orcid":false,"given":"Megandhita","family":"Sharasti","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6650-0559","authenticated-orcid":false,"given":"Evy","family":"Yunihastuti","sequence":"additional","affiliation":[{"name":"Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia"},{"name":"Department of Internal Medicine, University of Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2217\/fvl.12.130","article-title":"A Review of Experimental and Natural Infections of Animals with Monkeypox Virus between 1958 and 2012","volume":"8","author":"Parker","year":"2013","journal-title":"Future Virol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1699-0463.1959.tb00328.x","article-title":"A Pox-like Disease in Cynomolgus Monkeys","volume":"46","author":"Magnus","year":"1959","journal-title":"Acta Pathol. 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