{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T14:36:44Z","timestamp":1782571004029,"version":"3.54.5"},"reference-count":141,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"College of Pediatrics, Academy of Medicine of Malaysia"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccines"],"abstract":"<jats:p>Background\/Objectives: Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection in young children, especially during infancy, resulting in substantial morbidity and mortality. Methods: Acknowledging the real-world evidence on RSV immunization, the College of Pediatrics, Academy of Medicine of Malaysia, has appointed an expert panel to develop a position paper on recommendations for infant and\/or maternal vaccination against childhood RSV, specifically in the Malaysian context with year-round RSV activity. Results: Recognizing the potential constraints and limitations in the implementation process, the expert panel recommends targeted immunization with long-acting RSV monoclonal antibody (mAb) for high-risk infants as a pragmatic first step, with subsequent scale-up to universal immunization of infants when resources permit. Conclusions: Immunization is the most effective strategy to prevent RSV-related lower respiratory tract infection in childhood. Year-round maternal vaccination between 28 and 36 weeks\u2019 gestation, combined with immunization at six months for all infants, may potentially circumvent the unclear seasonality.<\/jats:p>","DOI":"10.3390\/vaccines14010059","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T13:35:47Z","timestamp":1767620147000},"page":"59","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recommendations on Respiratory Syncytial Virus (RSV) Immunization Strategies for Infants and Young Children in Countries with Year-Round RSV Activity"],"prefix":"10.3390","volume":"14","author":[{"given":"Fook Choe","family":"Cheah","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7498-2954","authenticated-orcid":false,"given":"Erwin Jiayuan","family":"Khoo","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, School of Medicine, IMU University, Kuala Lumpur 57000, Malaysia"},{"name":"Center for Bioethics, Harvard Medical School, Harvard University, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adli","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulkifli","family":"Ismail","sequence":"additional","affiliation":[{"name":"KPJ Selangor Specialist Hospital, Shah Alam 40300, Selangor, Malaysia"},{"name":"KPJ Healthcare University, Nilai 71800, Seremban, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rus Anida","family":"Awang","sequence":"additional","affiliation":[{"name":"Island Hospital Penang, Georgetown 10450, Penang, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Chun-Ern","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Hospital Tuanku Ja\u2019afar, Seremban 70300, Negeri Sembilan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick Wai Kiong","family":"Chan","sequence":"additional","affiliation":[{"name":"Gleneagles Hospital Kuala Lumpur, Kuala Lumpur 50450, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azanna","family":"Ahmad Kamar","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin Yun","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Hospital Canselor Tuanku Muhriz UKM, Cheras, Kuala Lumpur 56000, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal I-Ching","family":"Sam","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0813-8376","authenticated-orcid":false,"given":"Mohd Rizal","family":"Abdul Manaf","sequence":"additional","affiliation":[{"name":"Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asiah","family":"Kassim","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Hospital Tunku Azizah, Kuala Lumpur 50300, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/S0140-6736(22)00478-0","article-title":"Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: A systematic analysis","volume":"399","author":"Li","year":"2022","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Khor, C.S., Sam, I.C., Hooi, P.S., Quek, K.F., and Chan, Y.F. 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