{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T18:48:03Z","timestamp":1779907683181,"version":"3.53.1"},"reference-count":16,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>The actinobacillosis is rare and to date the biological profile of the agent is not yet fully understood. The knowledge about the possible hosts of the pathogen is incomplete and is generally only associated with granulomatous lesions in cattle and sheep. The primary organs involved are the mouth, tongue and pharynx. Human infection is extremely rare. Actinobacillus lignieresii is the causative agent of a rare bovine granulomatous disease known as \u201cwooden tongue\u201d. In this research, we describe a case of cerebral and ocular metastatic diffusion of granuloma due to infection with Actinobacillus lignieresii in cattle, probably resulting from primary oral localization. Diagnosis was made using histopathological assay which made it possible to highlight the typical lesion of actinobacillosis, and bacteriological assay that allowed to isolate the pathogen.<\/jats:p>","DOI":"10.3390\/vetsci10050311","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T01:37:01Z","timestamp":1682386621000},"page":"311","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Infection Due to Actinobacillus lignieresii in Cattle with Brain and Ocular Involvement: Histological and Microbiological Features"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6063-9517","authenticated-orcid":false,"given":"Antonio","family":"Salvaggio","sequence":"first","affiliation":[{"name":"Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato Paolo","family":"Giunta","sequence":"additional","affiliation":[{"name":"Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2183-4720","authenticated-orcid":false,"given":"Maurizio","family":"Percipalle","sequence":"additional","affiliation":[{"name":"Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Scalzo","sequence":"additional","affiliation":[{"name":"Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0528-4925","authenticated-orcid":false,"given":"Anna Maria Fausta","family":"Marino","sequence":"additional","affiliation":[{"name":"Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,24]]},"reference":[{"key":"ref_1","unstructured":"Carter, G.R., and Cole, J.R. (1990). Diagnostic Procedure in Veterinary Bacteriology and Mycology, Academic Press. [5th ed.]."},{"key":"ref_2","first-page":"487","article-title":"L\u2019actinobacillose","volume":"20","author":"Lignieres","year":"1982","journal-title":"Bull. Soc. Centr. M\u00e9d. V\u00e9t."},{"key":"ref_3","unstructured":"Radostits, O.M., and Done, S. (2007). Veterinary Medicine. A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats, Saunders Elsevier."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1177\/1040638717742621","article-title":"Natural lymphatic (\u201catypical\u201d) actinobacillosis in cattle caused by Actinobacillus lignieresii","volume":"30","author":"Caffarena","year":"2018","journal-title":"J. Vet. Diagn. 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[7th ed.]."}],"container-title":["Veterinary Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-7381\/10\/5\/311\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:22:39Z","timestamp":1760124159000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-7381\/10\/5\/311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,24]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["vetsci10050311"],"URL":"https:\/\/doi.org\/10.3390\/vetsci10050311","relation":{},"ISSN":["2306-7381"],"issn-type":[{"value":"2306-7381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,24]]}}}