{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:12:11Z","timestamp":1790662331059,"version":"4.1.0"},"reference-count":76,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T00:00:00Z","timestamp":1689033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Neonatal mortality in dogs reaches up to 40%. Due to the high rates, promptly detecting the causes and preventing newborns from dying are extremely important. Vitality evaluation, blood parameters, and the degree of meconium staining on the skin are valuable resources in canine perinatology. In this study, 435 puppies from 85 bitches close to parturition were recruited and divided into four quartiles according to the puppy\u2019s birth weight: Q1 (127\u2013200 g) n = 110 puppies, Q2 (201\u2013269 g) n = 108 puppies, Q3 (270\u2013388 g) n = 108 puppies, and Q4 (389\u2013464 g) n = 109 puppies. This experimental article aimed to report the effect of birth weight on the blood profile variables, the vitality of newborn puppies, and the meconium staining degree, integrating these three aspects. It was concluded that the weight of newborns was correlated with the degree of meconium staining, presenting more cases of severe meconium staining in the puppies of the highest birth weight group. The weight of the newborns was correlated with a higher number of stillbirths and alterations in the blood variables, showing the most severe cases of metabolic acidosis, hypoxia, and hypoglycemia in the puppies of the Q4 quartile. On the contrary, no statistically significant correlations were found between the weight of newborns and vitality. Nevertheless, the analysis of the results showed that the most vigorous puppies were found at Q1; however, at minute 60 after birth (AB), all the puppies in the four quartiles standardized their vitality scores.<\/jats:p>","DOI":"10.3390\/vetsci10070453","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T01:58:14Z","timestamp":1689040694000},"page":"453","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of Vitality, Blood Profile, and Degree of Meconium Staining on the Skin in Newborn Dogs According to Its Birth Weight"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0084-8135","authenticated-orcid":false,"given":"Karina","family":"Lezama-Garc\u00eda","sequence":"first","affiliation":[{"name":"PhD Program in Biological and Health Sciences, Doctorado en Ciencias Biol\u00f3gicas y de la Salud, Universidad Aut\u00f3noma Metropolitana, Mexico City 04960, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8681-4261","authenticated-orcid":false,"given":"Julio","family":"Mart\u00ednez-Burnes","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Tamaulipas, Victoria City 87000, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uri","family":"Baqueiro-Espinosa","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Queen\u2019s University Belfast, Belfast BT9 5DL, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Olmos-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Division of Biotechnology\u2014Bioterio and Experimental Surgery, Instituto Nacional de Rehabilitaci\u00f3n-Luis Guillermo Ibarra Ibarra (INR-LGII), Tlalpan, Mexico City 14389, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4271-2906","authenticated-orcid":false,"given":"Ismael","family":"Hern\u00e1ndez-\u00c1valos","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology and Veterinary Anesthesia, Facultad de Estudios Superiores Cuautitl\u00e1n, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Cuautitl\u00e1n Izcalli 54714, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1584-0654","authenticated-orcid":false,"given":"Adriana","family":"Dom\u00ednguez-Oliva","sequence":"additional","affiliation":[{"name":"Neurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Aut\u00f3noma Metropolitana (UAM), Unidad Xochimilco, Mexico City 04960, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0562-0367","authenticated-orcid":false,"given":"Daniel","family":"Mota-Rojas","sequence":"additional","affiliation":[{"name":"Neurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Aut\u00f3noma Metropolitana (UAM), Unidad Xochimilco, Mexico City 04960, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/rda.12787","article-title":"Assessment of canine neonatal viability-the Apgar score","volume":"51","author":"Veronesi","year":"2016","journal-title":"Reprod. 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