{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:59:58Z","timestamp":1793030398436,"version":"4.5.0"},"reference-count":74,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Swine influenza is a highly contagious respiratory disease caused by influenza A virus infection. Pigs play an important role in the overall epidemiology of influenza because of their ability to transmit influenza viruses of avian and human origin, which plays a potential role in the emergence of zoonotic strains with pandemic potential. The aim of our study was to assess the seroprevalence of Swine Influenza Viruses (swIAVs) in commercial pig farms in Greece. A total of 1416 blood samples were collected from breeding animals (gilts and sows) and pigs aged 3 weeks to market age from 40 different swIAV vaccinated and unvaccinated commercial farrow-to-finish pig farms. For the detection of anti-SIV antibodies, sera were analyzed using an indirect ELISA kit CIVTEST SUIS INFLUENZA\u00ae, Hipra (Amer, Spain). Of the total 1416 animals tested, 498 were seropositive, indicating that the virus circulates in both vaccinated (54% seroprevalence) and unvaccinated Greek pig farms (23% seroprevalence). In addition, maternally derived antibody (MDA) levels were lower in pigs at 4 and 7 weeks of age in unvaccinated farms than in vaccinated farms. In conclusion, our results underscore the importance of vaccination as an effective tool for the prevention of swIAV infections in commercial farrow-to-finish pig farms.<\/jats:p>","DOI":"10.3390\/vetsci10100599","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T04:28:08Z","timestamp":1696220888000},"page":"599","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Seroprevalence of Swine Influenza A Virus (swIAV) Infections in Commercial Farrow-to-Finish Pig Farms in Greece"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4955-0460","authenticated-orcid":false,"given":"Vasileios G.","family":"Papatsiros","sequence":"first","affiliation":[{"name":"Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3434-0877","authenticated-orcid":false,"given":"Georgios I.","family":"Papakonstantinou","sequence":"additional","affiliation":[{"name":"Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftherios","family":"Meletis","sequence":"additional","affiliation":[{"name":"Faculty of Public and One Health, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Koutoulis","sequence":"additional","affiliation":[{"name":"Department of Poultry Diseases, Faculty of Veterinary Science, School of Health Sciences, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoi","family":"Athanasakopoulou","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Maragkakis","sequence":"additional","affiliation":[{"name":"Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Labronikou","sequence":"additional","affiliation":[{"name":"Swine Technical Support, Hipra Hellas SA, 10441 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Terzidis","sequence":"additional","affiliation":[{"name":"Swine Technical Support, Hipra Hellas SA, 10441 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7051-1541","authenticated-orcid":false,"given":"Polychronis","family":"Kostoulas","sequence":"additional","affiliation":[{"name":"Faculty of Public and One Health, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2209-9772","authenticated-orcid":false,"given":"Charalambos","family":"Billinis","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1126\/science.1122438","article-title":"Global Patterns of Influenza a Virus in Wild Birds","volume":"312","author":"Olsen","year":"2006","journal-title":"Science"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.vetmic.2010.10.015","article-title":"Seroprevalence and Risk Factors of Swine Influenza in Spain","volume":"149","author":"Vilar","year":"2011","journal-title":"Vet. Microbiol."},{"key":"ref_3","unstructured":"Zimmerman, J.J., Karriker, L.A., Ramirez, A., Schwartz, K.J., and Stevenson, G.W. (2012). Diseases of Swine, Wiley-Blackwell. [10th ed.]."},{"key":"ref_4","first-page":"133","article-title":"History and Epidemiology of Swine Influenza in Europe","volume":"370","author":"Brown","year":"2013","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Simon, G., Larsen, L.E., D\u00fcrrwald, R., Foni, E., Harder, T., Reeth, K.V., Markowska-Daniel, I., Reid, S.M., Dan, A., and Maldonado, J. (2014). European Surveillance Network for Influenza in Pigs: Surveillance Programs, Diagnostic Tools and Swine Influenza Virus Subtypes Identified in 14 European Countries from 2010 to 2013. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0115815"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"9920","DOI":"10.1128\/JVI.00840-15","article-title":"Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013","volume":"89","author":"Watson","year":"2015","journal-title":"J. Virol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0378-1135(00)00164-4","article-title":"The Epidemiology and Evolution of Influenza Viruses in Pigs","volume":"74","author":"Brown","year":"2000","journal-title":"Vet. Microbiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0749-0720(15)30006-2","article-title":"Immunology of the Porcine Respiratory Disease Complex","volume":"17","author":"Thacker","year":"2001","journal-title":"Vet. Clin. N. Am. Food Anim. Pract."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.vetmic.2014.05.017","article-title":"Serological and Molecular Prevalence of Swine Influenza Virus on Farms in Northwestern Mexico","volume":"172","year":"2014","journal-title":"Vet. Microbiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1086\/524988","article-title":"Swine Influenza Virus: Zoonotic Potential and Vaccination Strategies for the Control of Avian and Swine Influenzas","volume":"197","author":"Thacker","year":"2008","journal-title":"J. Infect. Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.vetmic.2009.01.004","article-title":"Population Dynamics of Swine Influenza Virus in Farrow-to-Finish and Specialised Finishing Herds in the Netherlands","volume":"137","author":"Loeffen","year":"2009","journal-title":"Vet. Microbiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1099\/0022-1317-75-9-2183","article-title":"Potential for Transmission of Avian Influenza Viruses to Pigs","volume":"75","author":"Kida","year":"1994","journal-title":"J. Gen. Virol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1128\/mr.56.1.152-179.1992","article-title":"Evolution and Ecology of Influenza A Viruses","volume":"56","author":"Webster","year":"1992","journal-title":"Microbiol. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.molimm.2013.02.008","article-title":"Review: Influenza Virus in Pigs","volume":"55","author":"Crisci","year":"2013","journal-title":"Mol. Immunol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1136\/vr.145.5.123","article-title":"van Survey of Infectious Agents Involved in Acute Respiratory Disease in Finishing Pigs","volume":"145","author":"Loeffen","year":"1999","journal-title":"Vet. Rec."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1750-2659.2010.00175.x","article-title":"Transmission of Influenza A Viruses between Pigs and People, Iowa, 2002\u20132004","volume":"4","author":"Terebuh","year":"2010","journal-title":"Influenza Other Respir. Viruses"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1477-9552.2005.tb00126.x","article-title":"Updated Estimates of the Costs Associated with Thirty Four Endemic Livestock Diseases in Great Britain: A Note","volume":"56","author":"Bennett","year":"2005","journal-title":"J. Agric. Econ."},{"key":"ref_18","unstructured":"Brons, N., Neto, R., Vila, T., Pasini, M., and Joisel, F. (2021, January 12\u201315). Outbreak of Swine Influenza, Subtype H1N2: A Case Report and Its Financial Consequences. Proceedings of the 6th International Symposium on Emerging and Re-Emerging Pig Diseases, Barcelona, Spain. Available online: https:\/\/www.thepigsite.com\/articles\/proceedings-of-6th-international-symposium-on-emerging-and-reemerging-pig-diseases."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.vetmic.2011.12.027","article-title":"Pre-Infection of Pigs with Mycoplasma Hyopneumoniae Modifies Outcomes of Infection with European Swine Influenza Virus of H1N1, but Not H1N2, Subtype","volume":"157","author":"Deblanc","year":"2012","journal-title":"Vet. Microbiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.vetmic.2011.12.015","article-title":"Infectious Agents Associated with Respiratory Diseases in 125 Farrow-to-Finish Pig Herds: A Cross-Sectional Study","volume":"157","author":"Fablet","year":"2012","journal-title":"Vet. Microbiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0378-1135(02)00306-1","article-title":"Estimating the Incidence of Influenza-Virus Infections in Dutch Weaned Piglets Using Blood Samples from a Cross-Sectional Study","volume":"91","author":"Loeffen","year":"2003","journal-title":"Vet. Microbiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.vetmic.2007.07.011","article-title":"Failure of Protection and Enhanced Pneumonia with a US H1N2 Swine Influenza Virus in Pigs Vaccinated with an Inactivated Classical Swine H1N1 Vaccine","volume":"126","author":"Vincent","year":"2008","journal-title":"Vet. Microbiol."},{"key":"ref_23","unstructured":"World Organization for Animal Health (2018). Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, World Organization for Animal Health."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0168-1702(02)00027-8","article-title":"The Emergence of Novel Swine Influenza Viruses in North America","volume":"85","author":"Olsen","year":"2002","journal-title":"Virus Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/1297-9716-44-72","article-title":"Dynamics of Influenza A Virus Infections in Permanently Infected Pig Farms: Evidence of Recurrent Infections, Circulation of Several Swine Influenza Viruses and Reassortment Events","volume":"44","author":"Rose","year":"2013","journal-title":"Vet. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1297-9716-43-24","article-title":"Swine Influenza Virus Infection Dynamics in Two Pig Farms; Results of a Longitudinal Assessment","volume":"43","author":"Vilar","year":"2012","journal-title":"Vet. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.tvjl.2005.04.014","article-title":"Evidence of the Concurrent Circulation of H1N2, H1N1 and H3N2 Influenza A Viruses in Densely Populated Pig Areas in Spain","volume":"172","author":"Maldonado","year":"2006","journal-title":"Vet. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1750-2659.2008.00043.x","article-title":"Seroprevalence of H1N1, H3N2 and H1N2 Influenza Viruses in Pigs in Seven European Countries in 2002\u20132003","volume":"2","author":"Brown","year":"2008","journal-title":"Influ. Other Respir. Viruses"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0147-9571(85)90003-7","article-title":"Etude de la persistance d\u2019une activite du virus grippal H1N1 (swine) dans les elevages porcins en dehors des phases epidemiques","volume":"8","author":"Madec","year":"1985","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/zph.12235","article-title":"Serological Evidence of Pandemic H1N1 Influenza Virus Infections in Greek Swine","volume":"63","author":"Kyriakis","year":"2016","journal-title":"Zoonoses Public Health"},{"key":"ref_31","unstructured":"(2023, August 10). R: The R Project for Statistical Computing. Available online: https:\/\/www.r-project.org\/."},{"key":"ref_32","first-page":"1","article-title":"Fitting Linear Mixed-Effects Models Using Lme4","volume":"67","author":"Douglas","year":"2015","journal-title":"J. Stat. Softw."},{"key":"ref_33","first-page":"3","article-title":"Boot: Bootstrap R (S-Plus) Functions","volume":"1","author":"Canty","year":"2022","journal-title":"R Package Version"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Wickham, H. (2016). Ggplot2: Elegant Graphics for Data Analysis, Springer.","DOI":"10.1007\/978-3-319-24277-4"},{"key":"ref_35","unstructured":"Thacker, B.J., Cain, C.M., Janke, B.H., and Kinker, D.R. (1998). Swine Influenza Virus Passive Antibody Levels in Pigs from Vaccinated or Nonvaccinated Sows, Iowa State University."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Pardo, F.O.C., Wayne, S., Culhane, M.R., Perez, A., Allerson, M., and Torremorell, M. (2019). Effect of Strain-Specific Maternally-Derived Antibodies on Influenza A Virus Infection Dynamics in Nursery Pigs. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0210700"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s13567-016-0365-6","article-title":"Maternally-Derived Antibodies Do Not Prevent Transmission of Swine Influenza A Virus between Pigs","volume":"47","author":"Cador","year":"2016","journal-title":"Vet. Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1865-1682.2012.01367.x","article-title":"Detection of Airborne Influenza a Virus in Experimentally Infected Pigs with Maternally Derived Antibodies","volume":"61","author":"Corzo","year":"2014","journal-title":"Transbound. Emerg. Dis."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s13567-017-0466-x","article-title":"Longitudinal Study of Influenza A Virus Circulation in a Nursery Swine Barn","volume":"48","author":"Ferreira","year":"2017","journal-title":"Vet. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.rvsc.2019.10.015","article-title":"Limited Impact of Influenza A Virus Vaccination of Piglets in an Enzootic Infected Sow Herd","volume":"127","author":"Larsen","year":"2019","journal-title":"Res. Vet. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/tbed.12053","article-title":"Infection Dynamics of Pandemic 2009 H1N1 Influenza Virus in a Two-Site Swine Herd","volume":"61","author":"Allerson","year":"2014","journal-title":"Transbound Emerg. Dis."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Cador, C., Rose, N., Willem, L., and Andraud, M. (2016). Maternally Derived Immunity Extends Swine Influenza A Virus Persistence within Farrow-to-Finish Pig Farms: Insights from a Stochastic Event-Driven Metapopulation Model. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0163672"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"11886","DOI":"10.1038\/s41598-017-11272-3","article-title":"Multiple Genome Constellations of Similar and Distinct Influenza A Viruses Co-Circulate in Pigs During Epidemic Events","volume":"7","author":"Diaz","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.vetimm.2011.03.019","article-title":"The Influence of Age and Maternal Antibodies on the Postvaccinal Response against Swine Influenza Viruses in Pigs","volume":"142","author":"Pejsak","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.vetmic.2018.01.019","article-title":"Maternally-Derived Antibodies Do Not Inhibit Swine Influenza Virus Replication in Piglets but Decrease Excreted Virus Infectivity and Impair Post-Infectious Immune Responses","volume":"216","author":"Deblanc","year":"2018","journal-title":"Vet. Microbiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/BF01310622","article-title":"An ELISA for Detection of Antibodies against Influenza A Nucleoprotein in Humans and Various Animal Species","volume":"115","author":"Back","year":"1990","journal-title":"Arch. Virol."},{"key":"ref_47","unstructured":"Fleck, R., and Behrens, A. (2002). Evaluation of a Maternal Antibody Decay Curve for H1N1 Swine Influenza Virus Using the Hemagglutination Inhibition and the IDEXX ELISA Tests, American Association of Swine Veterinarians."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1186\/1743-422X-8-537","article-title":"Swine Influenza Virus Infection in Different Age Groups of Pigs in Farrow-to-Finish Farms in Thailand","volume":"8","author":"Takemae","year":"2011","journal-title":"Virol. J."},{"key":"ref_49","unstructured":"Davidson, N., and Stroud, D. (2006). African-Western Eurasian Flyways: Current Knowledge, Population Status and Future Challenges, The Stationery Office."},{"key":"ref_50","unstructured":"Lagring, R., Mpazigou, F., Koedam, N., and Chan, C.W. (2008, January 8\u201312). Monitoring Wetlands along the \u2018Western-Greek Bird Migration Route\u2019. Spatio-Temporal Change Detection Using Remote Sensing and GIS in Logarou Lagoon, Western Greece: A Pilot Study. Proceedings of the 6th European Conference on Ecological Restoration, Ghent, Begium."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Merken, R., Deboelpaep, E., Teunen, J., Saura, S., and Koedam, N. (2015). Wetland Suitability and Connectivity for Trans-Saharan Migratory Waterbirds. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0135445"},{"key":"ref_52","unstructured":"Karris, G., Barboutis, C., Chatzidakis, D., Xirouchakis, S., Vardanis, Y., Evangelidis, A., Dimitriadis, C., and Fransson, T. (2015, January 24\u201328). Arriving to Europe Extremely Lean\u2014Spring Migration of Some Passerines at Three Small Greek Islands. Proceedings of the 10th Conference of the European Ornithologists\u2019 Union, Badajoz, Spain."},{"key":"ref_53","first-page":"101","article-title":"Estimating the Population Size of Scopoli\u2019s Shearwaters (Calonectris Diomedea) Frequenting the Strofades Islands (Ionian Sea, Western Greece) by Raft Counts and Surveys of Breeding Pairs","volume":"13","author":"Karris","year":"2017","journal-title":"North-West. J. Zool."},{"key":"ref_54","unstructured":"Koutoulis, K. (2012, January 6). Present and Future of Poultry Industry in Greece. Proceedings of the 12th Pan-Hellenic Veterinary Congress, Athens, Greece."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"896","DOI":"10.7589\/0090-3558-46.3.896","article-title":"Prevalence of Antibodies to Type a Influenza Virus in Wild Avian Species Using Two Serologic Assays","volume":"46","author":"Brown","year":"2010","journal-title":"J. Wildl. Dis."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Adlhoch, C., Fusaro, A., Gonzales, J.L., Kuiken, T., Marangon, S., Mirinaviciute, G., and Niqueux, \u00c9. (2023). Avian Influenza Overview December 2022\u2013March 2023. EFSA J., 21, e07917.","DOI":"10.2903\/j.efsa.2023.7917"},{"key":"ref_57","first-page":"445","article-title":"Impediments to Wildlife Disease Surveillance, Research, and Diagnostics","volume":"315","author":"Stallknecht","year":"2007","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Blagodatski, A., Trutneva, K., Glazova, O., Mityaeva, O., Shevkova, L., Kegeles, E., Onyanov, N., Fede, K., Maznina, A., and Khavina, E. (2021). Avian Influenza in Wild Birds and Poultry: Dissemination Pathways, Monitoring Methods, and Virus Ecology. Pathogens, 10.","DOI":"10.3390\/pathogens10050630"},{"key":"ref_59","first-page":"2917","article-title":"The Role of Poultry Farms and Wild Birds During 2016\u20132017 Avian Influenza Epizootic in Europe","volume":"72","author":"Tsiouris","year":"2021","journal-title":"J. Hell. Vet. Med. Soc."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"544279","DOI":"10.3389\/fvets.2020.544279","article-title":"Herd-Level Risk Factors for Swine Influenza (H1N1) Seropositivity in West Java and Banten Provinces of Indonesia (2016\u20132017)","volume":"7","author":"Nurhayati","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"ref_61","unstructured":"Brown, J., Williams, O., Finch, S., Porter, B., and Bunn, J. (2023, August 10). Influenza Surveillance in Swine\u2014Procedures, Available online: https:\/\/www.aphis.usda.gov\/animal_health\/animal_dis_spec\/swine\/downloads\/influenza_surv_swine_proc_manual.pdf."},{"key":"ref_62","unstructured":"(2023, August 10). OIE\/FAO Strategy Document for Surveillance and Monitoring of Influenzas in Animals. Available online: https:\/\/www.fao.org\/animal-health\/situation-updates\/global-aiv-with-zoonotic-potential\/en."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1126\/science.1113310","article-title":"Public Health. Pathogen Surveillance in Animals","volume":"309","author":"Kuiken","year":"2005","journal-title":"Science"},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Harder, T., de Wit, S., Gonzales, J.L., Ho, J.H.P., Mulatti, P., Prajitno, T.Y., and Stegeman, A. (2023). Epidemiology-Driven Approaches to Surveillance in HPAI-Vaccinated Poultry Flocks Aiming to Demonstrate Freedom from Circulating HPAIV. Biologicals, 83.","DOI":"10.1016\/j.biologicals.2023.101694"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1003351","DOI":"10.3389\/fvets.2022.1003351","article-title":"Risk Factors Influencing Swine Influenza A Virus Infection in South Korea: A Systematic Review and Meta-Analysis of Prevalence and Seroprevalence","volume":"9","author":"Lee","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1007\/s00284-021-02520-x","article-title":"Widespread Prevalence of Antibodies Against Swine Influenza A (Pdm H1N1 09) Virus in Pigs of Eastern Uttar Pradesh, India","volume":"78","author":"Senthilkumar","year":"2021","journal-title":"Curr. Microbiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41426-018-0086-1","article-title":"Prospective Surveillance for Influenza A Virus in Chinese Swine Farms","volume":"7","author":"Anderson","year":"2018","journal-title":"Emerg. Microbes Infect."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/cid\/cix823","article-title":"Evidence for Cross-Species Influenza A Virus Transmission Within Swine Farms, China: A One Health, Prospective Cohort Study","volume":"66","author":"Ma","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/cid\/ciz865","article-title":"High Risk of Influenza Virus Infection Among Swine Workers: Examining a Dynamic Cohort in China","volume":"71","author":"Borkenhagen","year":"2020","journal-title":"Clin. Infect. Dis."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"20160138","DOI":"10.1098\/rsif.2016.0138","article-title":"High Turnover Drives Prolonged Persistence of Influenza in Managed Pig Herds","volume":"13","author":"Pitzer","year":"2016","journal-title":"J. R. Soc. Interface"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40813-021-00196-0","article-title":"Current and prospective control strategies of influenza A virus in swine","volume":"7","author":"Salvesen","year":"2021","journal-title":"Porc. Health Manag."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"e78618","DOI":"10.7554\/eLife.78618","article-title":"Vaccination Decreases the Risk of Influenza A Virus Reassortment but Not Genetic Variation in Pigs","volume":"11","author":"Li","year":"2022","journal-title":"eLife"},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-Vali\u00f1as, \u00c1., Valle, M., Wang, M., Darji, A., Cantero, G., Chiapponi, C., Segal\u00e9s, J., Ganges, L., and N\u00fa\u00f1ez, J.I. (2023). Vaccination against Swine Influenza in Pigs Causes Different Drift Evolutionary Patterns upon Swine Influenza Virus Experimental Infection and Reduces the Likelihood of Genomic Reassortments. Front. Cell. Infect. Microbiol., 13.","DOI":"10.3389\/fcimb.2023.1111143"},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Baudon, E., Peyre, M., Peiris, M., and Cowling, B.J. (2017). Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis. 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