{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:11:31Z","timestamp":1793124691822,"version":"4.5.0"},"reference-count":120,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T00:00:00Z","timestamp":1706832000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018818","name":"National Research, Development and Innovation Office, Budapest, Hungary","doi-asserted-by":"publisher","award":["2020-1.1.2-PIACI-KFI-2020-00002"],"award-info":[{"award-number":["2020-1.1.2-PIACI-KFI-2020-00002"]}],"id":[{"id":"10.13039\/501100018818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018818","name":"National Research, Development and Innovation Office, Budapest, Hungary","doi-asserted-by":"publisher","award":["SRF-001"],"award-info":[{"award-number":["SRF-001"]}],"id":[{"id":"10.13039\/501100018818","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Veterinary Medicine Budapest","award":["2020-1.1.2-PIACI-KFI-2020-00002"],"award-info":[{"award-number":["2020-1.1.2-PIACI-KFI-2020-00002"]}]},{"name":"University of Veterinary Medicine Budapest","award":["SRF-001"],"award-info":[{"award-number":["SRF-001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Uterine disease is an intensely studied part of dairy cattle health management as it heavily affects many commercial dairy farms and has serious economic consequences. Forms of the disease, pathophysiology, pathogens involved and the effects of uterine disease on the health and performance of cows have already been well described by various authors. Lately, researchers\u2019 attention has shifted towards the healthy microbiome of the uterus and the vagina to put emphasis on prevention rather than treatment. This aligns with the growing demand to reduce the use of antibiotics or\u2014whenever possible\u2014replace them with alternative treatment options in farm animal medicine. This review provides a comprehensive summary of the last 20 years of uterine disease research and highlights promising new areas for future studies.<\/jats:p>","DOI":"10.3390\/vetsci11020066","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T09:42:32Z","timestamp":1706866952000},"page":"66","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Uterine Disease in Dairy Cows: A Comprehensive Review Highlighting New Research Areas"],"prefix":"10.3390","volume":"11","author":[{"given":"Zs\u00f3ka","family":"V\u00e1rhidi","sequence":"first","affiliation":[{"name":"Department of Animal Hygiene, Herd Health and Mobile Clinic, University of Veterinary Medicine, 1078 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u00f6rgy","family":"Csik\u00f3","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology, University of Veterinary Medicine, 1078 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4597-8048","authenticated-orcid":false,"given":"\u00c1rp\u00e1d Csaba","family":"Bajcsy","sequence":"additional","affiliation":[{"name":"Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation, 30173 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6019-3508","authenticated-orcid":false,"given":"Viktor","family":"Jurkovich","sequence":"additional","affiliation":[{"name":"Centre for Animal Welfare, University of Veterinary Medicine, 1078 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.theriogenology.2005.04.022","article-title":"Prevalence of endometritis and its effects on reproductive performance of dairy cows","volume":"64","author":"Gilbert","year":"2005","journal-title":"Theriogenology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.3168\/jds.S0022-0302(06)72300-1","article-title":"Dairy cattle culling patterns, explanations and implications","volume":"89","author":"Hadley","year":"2006","journal-title":"J. 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