{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T20:34:31Z","timestamp":1788986071799,"version":"build-2803163510"},"reference-count":69,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T00:00:00Z","timestamp":1714262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordination for the Improvement of Higher Education Personnel (CAPES): Master schoolarship, Zebra Foundation","award":["1000452"],"award-info":[{"award-number":["1000452"]}]},{"name":"Coordination for the Improvement of Higher Education Personnel (CAPES): Master schoolarship, Zebra Foundation","award":["FC 2022.0"],"award-info":[{"award-number":["FC 2022.0"]}]},{"name":"Saint Louis Zoo","award":["1000452"],"award-info":[{"award-number":["1000452"]}]},{"name":"Saint Louis Zoo","award":["FC 2022.0"],"award-info":[{"award-number":["FC 2022.0"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>The use, misuse, and overuse of antimicrobials is one of the main public health threats of the 21st century. We investigated the risk factor of the presence of extended-spectrum, cephalosporin-resistant Enterobacterales in feces of non-domestic and domestic birds and other domestic animals in Piau\u00ed State, northeast Brazil. We collected a total of 387 cloacal and rectal swab samples of free-living birds, domestic birds, and domestic mammals in five municipalities: Amarante, \u00c1gua Branca, Lagoa Alegre, Parna\u00edba, and Teresina. A total of 59\/387 (15.2%) of these samples harbored extended spectrum beta-lactamase (ESBL)-producing Enterobacterales. Using the MALDI-TOF technique, we identified fifty-seven samples as Escherichia coli and two samples as Klebsiella pneumoniae. Teresina and Parna\u00edba had the highest prevalence of animals with resistant bacteria (32.1% and 27.1%, respectively) and highest exposure risk factor (OR of 16.06 and 8.58, respectively, and p &lt; 0.001 for all). Multidrug-resistant, ESBL-producing Enterobacterales were observed in 72.8% of the samples (43\/59). For the free-living birds, the positive samples belonged to a great kiskadee (Pitangus sulphuratus) and a semipalmated sandpiper (Calidris pusilla) in migratory and resident species, respectively. For domestic animals, the swine samples showed the highest prevalence of antimicrobial resistance. The lack of access to veterinary care and information regarding antimicrobial therapy, along with the easy access to antimicrobials without medical prescription, favors the inadequate use of antimicrobials in Piau\u00ed.<\/jats:p>","DOI":"10.3390\/vetsci11050195","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T06:13:22Z","timestamp":1714371202000},"page":"195","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["ESBL-Producing Enterobacterales at the Human\u2013Domestic Animal\u2013Wildlife Interface: A One Health Approach to Antimicrobial Resistance in Piau\u00ed, Northeastern Brazil"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1326-1125","authenticated-orcid":false,"given":"Sandy Kelly S. M.","family":"da Silva","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Sa\u00fade Animal na Amaz\u00f4nia, Universidade Federal do Par\u00e1 (UFPA), Bel\u00e9m 66075-110, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2845-4330","authenticated-orcid":false,"given":"Danny A.","family":"Fuentes-Castillo","sequence":"additional","affiliation":[{"name":"Departamento de Patolog\u00eda y Medicina Preventiva, Facultad de Ciencias Veterinarias, Universidad de Concepci\u00f3n (UDEC), Concepci\u00f3n 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"Ewbank","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Sanidad Animal (CISA-INIA), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28130 Valdeolmos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Sacrist\u00e1n","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Sanidad Animal (CISA-INIA), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28130 Valdeolmos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2999-3395","authenticated-orcid":false,"given":"Jos\u00e9 L.","family":"Cat\u00e3o-Dias","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Patologia Comparada de Animais Selvagens (LAPCOM), Faculdade de Medicina Veterin\u00e1ria e Zootecnia, Universidade de S\u00e3o Paulo (USP), S\u00e3o Paulo 05508-270, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5203-012X","authenticated-orcid":false,"given":"Anai\u00e1 P.","family":"Sev\u00e1","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Agr\u00e1rias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Bahia 45662-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0161-5800","authenticated-orcid":false,"given":"Nilton","family":"Lincopan","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Resist\u00eancia Bacteriana e Alternativas Terap\u00eauticas, Instituto de Ci\u00eancias Biom\u00e9dicas, Universidade de S\u00e3o Paulo (USP), S\u00e3o Paulo 05508-220, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2549-3636","authenticated-orcid":false,"given":"Sharon L.","family":"Deem","sequence":"additional","affiliation":[{"name":"Saint Loius Zoo, Institute for Conservation Medicine, St. Louis, MO 63110, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauro C. S.","family":"Feitosa","sequence":"additional","affiliation":[{"name":"Centro de Intelig\u00eancia em Agravos Tropicais Emergentes e Negligenciados (CIATEN) e Centro de Ci\u00eancias Agr\u00e1rias (CCA), Universidade Federal do Piau\u00ed (UFPI), Piau\u00ed 64049-550, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilian S.","family":"Catenacci","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o Sa\u00fade Animal na Amaz\u00f4nia, Universidade Federal do Par\u00e1 (UFPA), Bel\u00e9m 66075-110, Brazil"},{"name":"Saint Loius Zoo, Institute for Conservation Medicine, St. Louis, MO 63110, USA"},{"name":"Centro de Intelig\u00eancia em Agravos Tropicais Emergentes e Negligenciados (CIATEN) e Centro de Ci\u00eancias Agr\u00e1rias (CCA), Universidade Federal do Piau\u00ed (UFPI), Piau\u00ed 64049-550, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,28]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (WHO) (2017). 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