{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:34:42Z","timestamp":1776724482369,"version":"3.51.2"},"reference-count":62,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Innovet Italia srl","award":["INN-034_2021"],"award-info":[{"award-number":["INN-034_2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>The present study aimed at evaluating the effect of a gentle shampoo and a mousse containing Adelmidrol, tapioca starch and a non-prescription antimicrobial complex on seborrhoea and other clinical signs secondary to canine atopic dermatitis (cAD). Forty-six dogs with cAD-associated seborrhoea and\/or pruritus &gt; 4 cm on the pruritus visual analogue scale (P-VAS) and\/or bacterial\/Malassezia overgrowth were enrolled. The mousse was applied twice daily, and dogs were evaluated at days (D)0, 7, 14 and optionally 28, by means of a skin seborrheic index (SSI), P-VAS, cAD lesion index (CADLI), and a semiquantitative cytological score. The mean SSI value improved during the first two weeks (4.1 \u00b1 0.37 to 1.9 \u00b1 0.30; p &lt; 0.0001). The mean P-VAS score (cm) decreased from 6.6 \u00b1 0.19 at D0 to 3.8 \u00b1 0.31 at D14 (p &lt; 0.0001). The mean CADLI score dropped from 13.7 \u00b1 1.24 to 8.5 \u00b1 1.14 at D14 (p &lt; 0.001). The cytological score for bacteria and Malassezia decreased from 3.2 \u00b1 0.10 and 3.2 \u00b1 0.11, respectively, to 1.2 \u00b1 0.19 and 1.2 \u00b1 0.24 (p &lt; 0.0001). All the investigated signs further improved at D28. Altogether, these observations suggest that the tested protocol might be useful in managing cAD-associated signs.<\/jats:p>","DOI":"10.3390\/vetsci11060229","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T06:54:09Z","timestamp":1716360849000},"page":"229","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of a Protocol Combining a Non-Irritating Shampoo and an Adelmidrol-Based Adsorbent Mousse on Seborrhoea and Other Signs and Symptoms Secondary to Canine Atopic Dermatitis: A Multicenter, Open-Label Uncontrolled Clinical Trial"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2310-9813","authenticated-orcid":false,"given":"Chiara","family":"Noli","sequence":"first","affiliation":[{"name":"Servizi Dermatologici Veterinari, Strada Bedale della Ressia 2, 12016 Peveragno, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5424-4164","authenticated-orcid":false,"given":"Giada","family":"Morelli","sequence":"additional","affiliation":[{"name":"CeDIS (Science Information and Documentation Center), Innovet Italia Srl, Via Leonardo Da Vinci 3, 35030 Saccolongo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3956-6901","authenticated-orcid":false,"given":"Maria Federica","family":"della Valle","sequence":"additional","affiliation":[{"name":"CeDIS (Science Information and Documentation Center), Innovet Italia Srl, Via Leonardo Da Vinci 3, 35030 Saccolongo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7176-1980","authenticated-orcid":false,"given":"Carlo","family":"Schievano","sequence":"additional","affiliation":[{"name":"Innovative Statistical Research Srl, Prato della Valle 24, 35123 Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Skinalia Clinical Research Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Olivry, T., DeBoer, D.J., Favrot, C., Jackson, H.A., Mueller, R.S., Nuttall, T., Pr\u00e9laud, P., and for the International Committee on Allergic Diseases of Animals (2015). 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