{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:10:45Z","timestamp":1785528645172,"version":"3.56.0"},"reference-count":16,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T00:00:00Z","timestamp":1717459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Council for Scientific and Technological Development","award":["313680\/2023-0"],"award-info":[{"award-number":["313680\/2023-0"]}]},{"name":"Universidade Federal da Para\u00edba, Pr\u00f3-Reitoria de Pesquisa (PROPESQ-UFPB)","award":["313680\/2023-0"],"award-info":[{"award-number":["313680\/2023-0"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>A two-year-old female crossbreed dog, previously a stray with no known owner, was adopted and subsequently spayed. The dog exhibited weight loss over a period of two months and died suddenly during a leashed walk. Upon necropsy, enlargement of the submandibular, prescapular, and popliteal lymph nodes was noted. The intrathoracic cavity contained a substantial volume of yellowish-white fluid. Lymph nodes in the mediastinal and ventral thoracic centers were also enlarged, hemorrhagic, and friable. Microscopic examination revealed significant architectural changes in the lymph nodes, characterized by a pronounced cellular infiltrate consisting of lymphocytes and histiocytes, along with macrophages containing intracytoplasmic Leishmania amastigotes. Immunohistochemical analysis of the lymph nodes confirmed positive staining for Leishmania amastigotes. This case represents the first report of canine leishmaniasis associated with acute pleural effusion and sudden death.<\/jats:p>","DOI":"10.3390\/vetsci11060254","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T07:39:49Z","timestamp":1717486789000},"page":"254","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Canine Leishmaniosis Associated with Acute Pleural Effusion and Sudden Death in a Dog"],"prefix":"10.3390","volume":"11","author":[{"given":"Maria Caroline Pereira","family":"Brito","sequence":"first","affiliation":[{"name":"Graduate Program in Animal Science, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"},{"name":"Clinic 4Patas, Jo\u00e3o Pessoa 58030-330, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria de F\u00e1tima","family":"Sousa","sequence":"additional","affiliation":[{"name":"Graduate Program in Animal Science, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"},{"name":"Casa dos Criadores, Jo\u00e3o Pessoa 58040-330, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubia Avlade Guedes","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Graduate Program in Animal Science and Health, Universidade Federal de Campina Grande, Patos 58708-110, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markyson Tavares","family":"Linhares","sequence":"additional","affiliation":[{"name":"Undergraduate Course in Veterinary Medicine, Center for Agricultural Sciences, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5859-0915","authenticated-orcid":false,"given":"Lourdes Fernandez","family":"Riquelme","sequence":"additional","affiliation":[{"name":"Graduate Program in Animal Science, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wellida Karinne","family":"Lacerda","sequence":"additional","affiliation":[{"name":"Graduate Program in Animal Science, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2968-5766","authenticated-orcid":false,"given":"Ricardo Barbosa","family":"Lucena","sequence":"additional","affiliation":[{"name":"Graduate Program in Animal Science, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"},{"name":"Graduate Program in Animal Science and Health, Universidade Federal de Campina Grande, Patos 58708-110, PB, Brazil"},{"name":"Laboratory of Veterinary Pathology, Universidade Federal da Paraiba, Areia 58397-000, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,4]]},"reference":[{"key":"ref_1","first-page":"377","article-title":"Pleural effusion in adults\u2014Etiology, diagnosis, and treatment","volume":"116","author":"Jany","year":"2019","journal-title":"Dtsch. 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