{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:12:47Z","timestamp":1780499567532,"version":"3.54.1"},"reference-count":48,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T00:00:00Z","timestamp":1724716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"This study was supported by the Scientific Research Project of the Education Department of Jilin Province","award":["JJKH20231201KJ"],"award-info":[{"award-number":["JJKH20231201KJ"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Subacute ruminal acidosis (SARA) is a prevalent metabolic disorder in highly productive dairy cows that results in serious issues, including hoof lamellar injuries. This study aimed to investigate the efficacy of a carbonate buffer mixture (CBM) in preventing hoof lamella injury in dairy goats, a species also susceptible to SARA due to similar feeding practices over a 17-week period. Twenty-four healthy dairy goats were randomly assigned to three groups: control, SARA, and CBM groups. The control group received a standardized diet, whereas the SARA and CBM groups were subjected to a high-grain feeding regimen to induce SARA. The CBM group received a daily supplement of 10 g CBM mixed with their diet. Clinical assessments, including body temperature, rumen pH, inflammatory markers, matrix metalloproteinases (MMPs), and hoof lamellar injuries, were monitored throughout the study. The results showed that the CBM group maintained a more stable rumen pH and had lower levels of inflammatory markers than the SARA group did. The incidence of hoof lamellar injury was slightly lower in the CBM group. These findings suggest that long-term CBM supplementation may mitigate SARA-associated hoof lamella injury in dairy goats by regulating the rumen environment, fostering the growth of healthy bacterial communities, and by reducing the production of harmful metabolites. The use of CBM as a dietary supplement may have significant implications in improving the health, welfare, and productivity of dairy animals.<\/jats:p>","DOI":"10.3390\/vetsci11090395","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T06:19:01Z","timestamp":1724739541000},"page":"395","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of Carbonate Buffer Mixture in Preventing Hoof Lamella Injury Associated with Subacute Ruminal Acidosis in Dairy Goats"],"prefix":"10.3390","volume":"11","author":[{"given":"Maimaiti","family":"Tuniyazi","sequence":"first","affiliation":[{"name":"Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruibo","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naisheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University, Changchun 130062, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Fu, Y., He, Y., Xiang, K., Zhao, C., He, Z., Qiu, M., Hu, X., and Zhang, N. 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