{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T02:53:12Z","timestamp":1783479192055,"version":"3.55.0"},"reference-count":47,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Guangxi Science and Technology Bureau","award":["AB21238003"],"award-info":[{"award-number":["AB21238003"]}]},{"name":"Guangxi Science and Technology Bureau","award":["Z2022198"],"award-info":[{"award-number":["Z2022198"]}]},{"name":"Guangxi Agricultural and Rural Bureau, China","award":["AB21238003"],"award-info":[{"award-number":["AB21238003"]}]},{"name":"Guangxi Agricultural and Rural Bureau, China","award":["Z2022198"],"award-info":[{"award-number":["Z2022198"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Feline coronavirus (FCoV), as one of the important pathogens of feline viral gastroenteritis, has been attracting great attention. A total of 1869 rectal and nasal swabs, feces, and ascites samples were collected from eight regions in Guangxi province during 2021\u20132024. The multiplex RT-qPCR established in our laboratory was used to test these samples for FCoV, and 17.66% (330\/1869) of the samples were positive for FCoV. The S, M, and N genes of 63 FCoV-positive samples were amplified and sequenced, and the genetic and evolutionary characteristics were analyzed. Similarity analysis showed that the nucleotide and amino acid homologies of S, M, and N genes were 81.2\u201399.6% and 70.2\u201399.5%, 89.9\u2013100% and 91.6\u2013100%, and 90.1\u2013100% and 91.5\u2013100%, respectively. Phylogenetic analysis revealed that all 63 FCoV strains, based on S gene sequences, belonged to type I FCoV (FCoV-I), and were clustered with Chinese strains and the Netherlands UU strains. Recombinant signals were detected in the S gene of strains GXLZ03-2022, GXLZ08-2022, and CCoV GD\/2020\/X9. The results suggest that FCoV is still prevalent in the Guangxi province of southern China, and the prevalent FCoV strains show high genetic diversity and novel epidemic characteristics.<\/jats:p>","DOI":"10.3390\/vetsci11100455","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T16:16:37Z","timestamp":1727280997000},"page":"455","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Genetic and Phylogenetic Analysis of Feline Coronavirus in Guangxi Province of China from 2021 to 2024"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1023-9635","authenticated-orcid":false,"given":"Kaichuang","family":"Shi","sequence":"first","affiliation":[{"name":"School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China"},{"name":"College of Animal Science and Technology, Guangxi University, Nanning 530005, China"},{"name":"Guangxi Center for Animal Disease Control and Prevention, Nanning 530001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyi","family":"He","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Guangxi University, Nanning 530005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwen","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Guangxi University, Nanning 530005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9625-0527","authenticated-orcid":false,"given":"Feng","family":"Long","sequence":"additional","affiliation":[{"name":"Guangxi Center for Animal Disease Control and Prevention, Nanning 530001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yandi","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Guangxi University, Nanning 530005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwen","family":"Yin","sequence":"additional","affiliation":[{"name":"Guangxi Center for Animal Disease Control and Prevention, Nanning 530001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Pan","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongqiang","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Guangxi University, Nanning 530005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuping","family":"Feng","sequence":"additional","affiliation":[{"name":"Guangxi Center for Animal Disease Control and Prevention, Nanning 530001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"001843","DOI":"10.1099\/jgv.0.001843","article-title":"ICTV virus taxonomy profile: Coronaviridae 2023","volume":"104","author":"Woo","year":"2023","journal-title":"J. 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