{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:39:32Z","timestamp":1789663172838,"version":"4.0.1"},"reference-count":31,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o Arauc\u00e1ria de Apoio ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Estado do Paran\u00e1 (FA)","award":["Ed. N\u00ba 1010\/GR\/UFFS\/2018"],"award-info":[{"award-number":["Ed. 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N\u00ba 1010\/GR\/UFFS\/2018"]}]},{"name":"European Next Generation, EU\/PRTR","award":["RYC2021-034764-I"],"award-info":[{"award-number":["RYC2021-034764-I"]}]},{"name":"European Next Generation, EU\/PRTR","award":["MCIN\/AEI\/10.13039\/501100011033"],"award-info":[{"award-number":["MCIN\/AEI\/10.13039\/501100011033"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>We evaluated the surgical stress response of dogs undergoing three ovariohysterectomy (OVH) techniques. Twenty-nine healthy females were allocated into groups: celiotomy and ligature (CelioSut), celiotomy and bipolar energy (CelioBip), and a video-assisted technique using two portals and bipolar energy (VidBip). Clinical evaluation was performed, and the following blood analyses were determined: acute phase proteins (C-reactive protein and haptoglobin), white blood cell counting (WBC), and biomarkers of oxidative status. The VidBip required more time despite a smaller incision, lower heart rate, and earlier feeding and urination. All groups had high white blood cells counts; the C-reactive protein (CRP) levels peaked at 6 and 12 h in all groups and was higher in the CelioBip and VidBip groups compared to CelioSut; haptoglobin concentrations peaked at 48 h in all groups and increased in dogs of the CelioSut group. Trolox equivalent antioxidant capacity, ferric reducing ability of plasma, cupric reducing antioxidant capacity, and advanced oxidation protein were not significantly different among the groups or time points. Total thiol concentrations were lower in CelioBip and CelioSut groups. All surgical techniques induced an inflammatory and oxidative stress response, but the video-assisted technique produced early clinical recovery. The bipolar device produces fewer disturbances than suspensory ligament rupture and ligature.<\/jats:p>","DOI":"10.3390\/vetsci11110583","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T11:58:07Z","timestamp":1732017487000},"page":"583","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Changes in Biomarkers of Inflammation and Oxidative Status in Dogs Subjected to Celiotomy or Video-Assisted Ovariohysterectomy"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4553-7114","authenticated-orcid":false,"given":"Fab\u00edola","family":"Dalmolin","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Sa\u00fade, Bem-estar e Produ\u00e7\u00e3o Animal Sustent\u00e1vel na Fronteira Sul (PPG-SBPAS), Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9293-4147","authenticated-orcid":false,"given":"Camila Peres","family":"Rubio","sequence":"additional","affiliation":[{"name":"Department of Animal Surgery and Medicine, University of Murcia, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8050-083X","authenticated-orcid":false,"given":"Carla Sordi","family":"Furlanetto","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Sa\u00fade, Bem-estar e Produ\u00e7\u00e3o Animal Sustent\u00e1vel na Fronteira Sul (PPG-SBPAS), Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5524-8933","authenticated-orcid":false,"given":"Rafael","family":"Steffens","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Sa\u00fade, Bem-estar e Produ\u00e7\u00e3o Animal Sustent\u00e1vel na Fronteira Sul (PPG-SBPAS), Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9828-4468","authenticated-orcid":false,"given":"Najla Ibrahim Isa Abdel","family":"Hadi","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Sa\u00fade, Bem-estar e Produ\u00e7\u00e3o Animal Sustent\u00e1vel na Fronteira Sul (PPG-SBPAS), Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5328-5025","authenticated-orcid":false,"given":"Adriellen de Lima","family":"da Silva","sequence":"additional","affiliation":[{"name":"Curso de Medicina Veterin\u00e1ria, Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2323-6211","authenticated-orcid":false,"given":"Paloma","family":"Tomazi","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Sa\u00fade, Bem-estar e Produ\u00e7\u00e3o Animal Sustent\u00e1vel na Fronteira Sul (PPG-SBPAS), Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6833-0338","authenticated-orcid":false,"given":"Bernardo Nascimento","family":"Antunes","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Medicina Veterin\u00e1ria (PPGMV), Universidade Federal de Santa Maria (UFSM), Santa Maria 97105-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3882-465X","authenticated-orcid":false,"given":"Fabiana","family":"Elias","sequence":"additional","affiliation":[{"name":"Curso de Medicina Veterin\u00e1ria, Universidade Federal da Fronteira Sul (UFFS), Realeza 85770-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8297-6979","authenticated-orcid":false,"given":"Elizabeth Moreira dos Santos","family":"Schmidt","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, S\u00e3o Paulo State University (FMVZ-UNESP), Campus Botucatu, Botucatu 18618-681, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9252-8512","authenticated-orcid":false,"given":"Maur\u00edcio Veloso","family":"Brun","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Medicina Veterin\u00e1ria (PPGMV), Universidade Federal de Santa Maria (UFSM), Santa Maria 97105-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Schwarzkopf, I., Van Goethem, B., Vandekerckhove, P.M., and De Rooster, H. 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