{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:23:40Z","timestamp":1791930220214,"version":"4.3.4"},"reference-count":156,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T00:00:00Z","timestamp":1735344000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Gallbladder mucocele, cholelithiasis, choledocholithiasis, and cholecystitis are significant contributors to morbidity and mortality in dogs. The exact etiology of these conditions remains poorly understood, though various factors, such as endocrinopathies, dyslipidemia, and impaired gallbladder motility, have been suggested as potential contributors. Surgical intervention has been described as the first choice of treatment when biliary rupture or obstruction is suspected; however, medical management may be an important part of therapeutic or preventative strategy. Reports of medical management typically involve the use of a choleretic used to stimulate the flow of bile into the duodenum or substances that act as a \u201chepatoprotective\u201d agent such as S-adenosylmethionine. In people, some nutrients appear to modify bile flow and are used as agents in the prevention and treatment of these conditions in the gallbladder. This paper provides a review of the literature about possible nutritional factors involved in the pathogenesis and treatment of canine gallbladder mucocele and cholelithiasis. Opportunities for the prevention and treatment of common biliary diseases in dogs may include the reduction of dietary fat, control of hyperlipidemia with omega-3 and fiber supplementation, ensuring an adequate supply of amino acids such as methionine and tryptophan, and the evaluation of vitamins such as vitamin D.<\/jats:p>","DOI":"10.3390\/vetsci12010005","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T14:21:12Z","timestamp":1735654872000},"page":"5","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Nutritional Factors Related to Canine Gallbladder Diseases\u2014A Scoping Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6198-9367","authenticated-orcid":false,"given":"Fabio","family":"Teixeira","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo-Brazil, S\u00e3o Paulo 05508270, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7170-7703","authenticated-orcid":false,"given":"Kathleen","family":"Aicher","sequence":"additional","affiliation":[{"name":"Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, 4474 TAMU, College Station, TX 77843-4474, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Duarte","sequence":"additional","affiliation":[{"name":"Gastrovet, S\u00e3o Paulo 04077003, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Washabau, R.J., and Day, M.J. 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