{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:14:31Z","timestamp":1787030071322,"version":"build-2736575974"},"reference-count":84,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T00:00:00Z","timestamp":1738972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jilin province science and technology development planning grant program","award":["20210508021RQ"],"award-info":[{"award-number":["20210508021RQ"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>This study presents a systematic review and meta-analysis of studies on tick-borne encephalitis virus (TBEV) prevalence in ticks and human hosts in China, published between 2000 and 2023. Extensive searches were conducted on four databases\u2014PubMed, CNKI, VIP, and Wan Fang. The findings indicated overall pooled prevalence estimates of TBEV infection in ticks and humans of 5.8% and 9.0%, respectively. The prevalence of TBEV in ticks was 4.8% (95%CI, 4.5\u20137.1%) during 2000\u20132010 and increased to 6.3% (95%CI, 4.7\u20137.8%) during 2011\u20132023, and was mainly distributed in Jilin (13.4%; 95%CI, 8.3\u201318.4%) and Inner Mongolia (4.5%; 95%CI, 1.8\u20137.1%). The prevalence of TBEV was higher in Dermacentor silvarum than in other tick species (8.1%; 95%CI, 3.2\u201312.9%). The seroprevalence of TBEV in humans increased from 4.7% (95%CI, 2.9\u20136.4%) during 2000\u20132010 to 17.6% (95%CI, 11.3\u201323.8%) during 2011\u20132023. Simultaneously, the analysis results of the population characteristics showed that females, forestry workers, military personnel, and farmers were found to be susceptible, and the highest seroprevalence was noted among homemakers and unemployed individuals. There were certain differences in the seroprevalence among populations in different provinces, especially in Xinjiang and Heilongjiang. This study can provide a reference for a more comprehensive and in-depth investigation of ticks and humans infected with TBEV in China.<\/jats:p>","DOI":"10.3390\/vetsci12020146","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T04:44:03Z","timestamp":1739162643000},"page":"146","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Prevalence of Tick-Borne Encephalitis Virus in the Ticks and Humans of China from 2000 to 2023: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7879-0792","authenticated-orcid":false,"given":"Hongyu","family":"Qin","sequence":"first","affiliation":[{"name":"Key Lab of Preventive Veterinary Medicine in Jilin Province, Jilin 132101, China"},{"name":"College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5766-287X","authenticated-orcid":false,"given":"Xiu","family":"Xin","sequence":"additional","affiliation":[{"name":"Key Lab of Preventive Veterinary Medicine in Jilin Province, Jilin 132101, China"},{"name":"College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qichao","family":"Tang","sequence":"additional","affiliation":[{"name":"Key Lab of Preventive Veterinary Medicine in Jilin Province, Jilin 132101, China"},{"name":"College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xujing","family":"Feng","sequence":"additional","affiliation":[{"name":"Key Lab of Preventive Veterinary Medicine in Jilin Province, Jilin 132101, China"},{"name":"College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baishuang","family":"Yin","sequence":"additional","affiliation":[{"name":"Key Lab of Preventive Veterinary Medicine in Jilin Province, Jilin 132101, China"},{"name":"College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/nature06536","article-title":"Global trends in emerging infectious diseases","volume":"451","author":"Jones","year":"2008","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41392-024-01917-x","article-title":"Emerging and reemerging infectious diseases: Global trends and new strategies for their prevention and control","volume":"9","author":"Wang","year":"2024","journal-title":"Signal Transduct. 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