{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:52:39Z","timestamp":1760057559920,"version":"build-2065373602"},"reference-count":59,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key Discipline of Veterinary Medicine of Henan Province","award":["312","XJK202202","241111113400"],"award-info":[{"award-number":["312","XJK202202","241111113400"]}]},{"name":"Key Discipline of Preventive Veterinary Medicine of Henan University of Animal Husbandry and Economy","award":["312","XJK202202","241111113400"],"award-info":[{"award-number":["312","XJK202202","241111113400"]}]},{"name":"Henan Province key research and development project","award":["312","XJK202202","241111113400"],"award-info":[{"award-number":["312","XJK202202","241111113400"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Aeromonas veronii (A. veronii) is a ubiquitous bacterium in terrestrial and aquatic environments. It has a significant impact on animal and human health, with it becoming an emerging crucial pathogen worldwide. However, there have been no reports of mute swan infections. In the present study, after an observation of pathological changes, one bacterial strain isolated from a dead migratory mute swan was identified as A. veronii HNZZ-1\/2022 based on its morphology, matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry (MALDI-TOF MS), and sequence analysis of the 16S rRNA and gyrB genes. To explore its pathogenicity, virulence gene detection and a gosling infection experiment were subsequently carried out, respectively. Six virulence genes for cytotonic enterotoxins (alt), lateral elastase (ela), lipase (lip), cytotoxic enterotoxin (act), aerolysin (aerA), and polar flagellin (fla) were present in the template DNA of A. veronii HNZZ-1\/2022. Experimentally infected goslings exhibited hemorrhages of various different degrees in multiple organs. The half-maximal lethal dose (LD50) value of A. veronii strain HNZZ-1\/2022 was estimated to be 3.48 \u00d7 108 colony forming units (CFUs) per mL for goslings. An antimicrobial susceptibility test showed that the A. veronii HNZZ-1\/2022 strain was resistant to meropenem, ampicillin, and enrofloxacin. To date, this is the first report of A. veronii in migratory mute swans, thus expanding the currently known host spectrum. These results suggest that the migratory mute swan is a new host for A. veronii and demonstrate the need for extensive surveillance and research of A. veronii to minimize its transmission between animals, the environment, and humans.<\/jats:p>","DOI":"10.3390\/vetsci12020164","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T04:03:35Z","timestamp":1739419415000},"page":"164","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring Aeromonas veronii in Migratory Mute Swans (Cygnus olor): A Debut Report and Genetic Characterization"],"prefix":"10.3390","volume":"12","author":[{"given":"Zhifeng","family":"Peng","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunyan","family":"Gao","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongxing","family":"Qiao","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huimin","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamin","family":"Sheng","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojie","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baojun","family":"Li","sequence":"additional","affiliation":[{"name":"Zhengzhou Zoo, Zhengzhou 450000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoliang","family":"Chao","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Kang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuanzhou","family":"Bian","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yang, C., Guo, M., Yang, H., Wen, Y., Zhu, Z., Wang, T., Zhu, J., and Chen, L. 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