{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:36:31Z","timestamp":1792802191760,"version":"4.5.0"},"reference-count":33,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>In 2018, the Food and Drug Administration (FDA) reported cases of dilated cardiomyopathy (DCM) in dogs, including breeds without known genetic predisposition, fed diets containing a high proportion of legumes or potatoes, many labeled grain-free. Despite concerns, grain-free diets remain increasingly popular. This narrative review focuses on the peer-reviewed literature and summarizes recent studies evaluating the effects of grain-free diets on canine cardiac health, with emphasis on taurine deficiency, metabolic alterations, and emerging hypotheses extending beyond nutritional inadequacy. These findings suggest a strong link between diet and DCM, particularly regarding legumes. Dogs of various breeds showed larger left ventricular diameters, reduced systolic function, and increased premature ventricular complexes when fed non-traditional, grain-free, legume-rich diets compared to those on traditional, low-legume diets. Many affected dogs improved clinically and functionally with dietary changes and treatment, suggesting nutritional DCM could be reversible. Though mechanisms remain unclear, the research highlights the potential roles of legumes, particularly peas, in the gut microbiota and fiber-related bile acid metabolism. This review also distinguishes taurine-deficiency-related DCM as a separate form, with certain breeds, notably Golden Retrievers, being more susceptible. Overall, further studies are required to better understand the role of nutrition in canine cardiac health.<\/jats:p>","DOI":"10.3390\/vetsci12111106","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T09:44:53Z","timestamp":1763631893000},"page":"1106","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Role of Diet as a Predisposing Factor for Dilated Cardiomyopathy in Dogs: A Narrative Review"],"prefix":"10.3390","volume":"12","author":[{"given":"L\u00e9a","family":"Mornard","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, EUVG\u2014Vasco da Gama University School, Avenida Jos\u00e9 R. Sousa Fernandes 197, 3020-210 Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0369-3469","authenticated-orcid":false,"given":"Anna Carolina Massara","family":"Brasileiro","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, EUVG\u2014Vasco da Gama University School, Avenida Jos\u00e9 R. Sousa Fernandes 197, 3020-210 Coimbra, Portugal"},{"name":"CIVG\u2014Vasco da Gama Research Center, Avenida Jos\u00e9 R. Sousa Fernandes 197, 3020-210 Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio","family":"Marcondes-Santos","sequence":"additional","affiliation":[{"name":"CIVG\u2014Vasco da Gama Research Center, Avenida Jos\u00e9 R. Sousa Fernandes 197, 3020-210 Coimbra, Portugal"},{"name":"School of Agriculture, Santar\u00e9m Polytechnic University, Quinta do Galinheiro\u2014S. Pedro, 2001-904 Santar\u00e9m, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"ref_1","unstructured":"Chetboul, V. (2023). L\u2019\u00e9chocardiographie Du Chien et Du Chat: De la Pratique \u00e0 L\u2019interpr\u00e9tation Raisonn\u00e9e, MED\u2019COM."},{"key":"ref_2","unstructured":"Loriot, N. (2014). Vade-Mecum D\u2019\u00e9chocardiographie Du Chien et Du Chat: Comment Bien D\u00e9buter, MED\u2019COM."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.2460\/javma.253.11.1390","article-title":"Diet-Associated Dilated Cardiomyopathy in Dogs: What Do We Know?","volume":"253","author":"Freeman","year":"2018","journal-title":"J. Am. Vet. Med. 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