{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T09:30:43Z","timestamp":1764581443322,"version":"3.46.0"},"reference-count":39,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Laparoscopic salpingectomy is a minimally invasive surgery that requires careful anesthetic management due to the effects of intra-abdominal gas insufflation. In this retrospective study, baboons (Papio hamadryas) were treated with two induction protocols: medetomidine\u2013ketamine (MK; n = 16) and medetomidine\u2013tiletamine\u2013zolazepam (MZ; n = 12) via intramuscular injection. A laryngeal mask (LMA) was used for airway management and anesthesia was maintained with isoflurane in 100% oxygen. For statistical analysis, the following parameters were analyzed via two-way ANOVA: heart rate (HR), respiratory rate (RR), systolic, diastolic, and mean arterial blood pressure (SAP, DAP, and MAP), end-tidal carbon dioxide (EtCO2), and peripheral oxygen saturation (SpO2) recorded five minutes before pneumoperitoneum (PREP), after abdominal insufflation (PP1), at 10 (PP2) and 20 (PP3) minutes post-insufflation, and 5 min after pneumoperitoneum interruption (POSTP). HR and RR were statistically significantly higher (p &lt; 0.05) in the MK group compared to the MZ group at all time points of the study. EtCO2 was significantly higher (p &lt; 0.05) in the MZ group at PP2, PP3, and POSTP time points. The incidence of hypotension was significantly greater in the MZ group (45.5%) compared to the MK group (6.25%). Hypercapnia was observed in all baboons sedated with the MZ protocol compared to 12.5% of the MK group. As a result, the MK protocol provided greater cardiorespiratory stability during laparoscopic surgery.<\/jats:p>","DOI":"10.3390\/vetsci12121134","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T08:13:49Z","timestamp":1764576829000},"page":"1134","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Cardiorespiratory Effects of Two Balanced Anesthesia Protocols in Baboons (Papio hamadryas) Undergoing Laparoscopic Salpingectomy"],"prefix":"10.3390","volume":"12","author":[{"given":"Roberta","family":"Pizzi","sequence":"first","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1397-6109","authenticated-orcid":false,"given":"Claudia","family":"Piemontese","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5803-2070","authenticated-orcid":false,"given":"Caterina","family":"Vicenti","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Barazia","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6252-3179","authenticated-orcid":false,"given":"Marzia","family":"Stabile","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Acquafredda","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4963-8673","authenticated-orcid":false,"given":"Luca","family":"Lacitignola","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4917-355X","authenticated-orcid":false,"given":"Marta","family":"Guadalupi","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6261-3967","authenticated-orcid":false,"given":"Pietro","family":"Laricchiuta","sequence":"additional","affiliation":[{"name":"Zoosafari, 72015 Fasano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2085-376X","authenticated-orcid":false,"given":"Francesco","family":"Staffieri","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00167957","article-title":"Cycle synchrony and probability of conception in female hamadryas baboons Papio hamadryas","volume":"35","author":"Zinner","year":"1994","journal-title":"Behav. 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