{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:19:23Z","timestamp":1788326363073,"version":"build-2803163510"},"reference-count":26,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022271","name":"Faculty of Veterinary Medicine, Kasetsart University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022271","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/05gzceg21","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet. Sci.","Veterinary Sciences"],"abstract":"<jats:p>The objective of this study was to compare fecal egg count (FEC) and serum malondialdehyde (MDA) concentration in naturally parasite-infected goats following administration of an anthelmintic drug and Mitragyna speciosa Korth. as the control and treatment groups, respectively. A total of 34 female goats were randomly allocated into two groups. The control group received albendazole at a dose of 15 mg\/kg on the first day of the experiment. Then followed by a daily placebo until day 21. The treatment group was orally administered 5 g\/head of dried Mitragyna speciosa Korth. daily for 21 days. Hematological parameters were evaluated on days 0 and 21, while blood biochemical parameters, including blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT), were measured on day 0 and at 7-day intervals until day 35. Fecal egg count and serum MDA concentration were determined on day 0 and every 7 days until day 42. The results showed that plasma protein levels were significantly affected by time (p &lt; 0.05) and group (p &lt; 0.05), while red blood cell count was significantly influenced by time (p &lt; 0.05). No significant group effects were observed for BUN, creatinine, AST, and GGT. However, AST showed a significant effect over time (p &lt; 0.05). Hematological and blood biochemical parameters remained within physiological ranges in both groups, with no evidence of kratom-associated toxicity. Log2-transformed fecal egg counts per gram of feces (Log2-EPG) showed significant time and time \u00d7 group interaction effects (p &lt; 0.001 and p = 0.008, respectively). Fecal egg count reduction test (FECRT) showed significant time and time \u00d7 group interaction effects (p = 0.009 and p = 0.013, respectively). Serum MDA was significantly lower in the kratom group only at day 7 (p &lt; 0.05). In conclusion, Mitragyna speciosa Korth. supplementation did not significantly reduce fecal egg count compared to conventional anthelmintic treatment but demonstrated a transient effect on oxidative stress, as indicated by changes in serum MDA concentration.<\/jats:p>","DOI":"10.3390\/vetsci13090893","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:33:32Z","timestamp":1788262412000},"page":"893","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Oral Supplementation of Kratom (Mitragyna speciosa Korth.) on Gastrointestinal Nematodes and Serum Lipid Peroxidation in Crossbred Saanen Goats"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5625-917X","authenticated-orcid":false,"given":"Sopon","family":"Veerapan","sequence":"first","affiliation":[{"name":"Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen, Nakhon Pathom 73140, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Supawit","family":"Triwutanon","sequence":"additional","affiliation":[{"name":"Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen, Nakhon Pathom 73140, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7659-9644","authenticated-orcid":false,"given":"Theera","family":"Rukkwamsuk","sequence":"additional","affiliation":[{"name":"Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen, Nakhon Pathom 73140, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hamid, L., Alsayari, A., Tak, H., Mir, S.A., Almoyad, M.A.A., Wahab, S., and Bader, G.N. 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