{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:30:39Z","timestamp":1789122639501,"version":"build-2803163510"},"reference-count":63,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet. Sci.","Veterinary Sciences"],"abstract":"<jats:p>This study aimed to evaluate whether adding curcumin to prepartum cows\u2019 diets positively affects metabolism, immune response, milk and colostrum production and quality. Forty Holstein cows were divided into two homogeneous groups, with 20 animals per treatment, balanced according to milk production (kg\/day) during the previous lactation and parity. The experiment was conducted in a continuous trial, with each groups of animals randomly assigned to one of the treatments: (a) addition of curcumin to the diet (152 mg\/day) in the prepartum period; (b) without additive, used as control. The study was carried out on a commercial farm in a compost barn confinement system. Cows were fed with curcumin only during the 21-day prepartum period. Postpartum monitoring, data collection, and sampling were conducted for 28 days without curcumin. After calving, the animals had access to free-flow robotic milking. The variables colostrum production and quality were evaluated, followed by milk analysis. Blood parameters for biochemical, proteinogram and antioxidant analyses were collected at strategic periods of the experiment. We found that the prepartum treatment had no effect on the milk production, composition and physicochemical properties (p &gt; 0.05). The serum concentrations of beta-hydroxybutyrate (BHBA), albumin, AST, ALT and GGT of the cows were not affected by the treatments, while the globulin levels were higher in the curcumin group on the seventh day postpartum (p = 0.05). The addition of curcumin caused immunomodulation on globulins, where higher serum concentrations of IgA, Ig heavy chain, haptoglobin and transferrin (p \u2264 0.001) were observed, as well as lower serum levels of C-reactive protein and ceruloplasmin (p \u2264 0.0002). The serum and colostrum oxidant\/antioxidant profile did not show any difference when curcumin was used prepartum, nor did the colostrum brix concentration. It was concluded that curcumin supplementation increased serum globulin levels, improving the immune response. Although the curcumin diet was offered only in the prepartum period, there was a positive impact on the immune response of cows for up to seven days postpartum, the most critical moment in dairy cattle farming.<\/jats:p>","DOI":"10.3390\/vetsci13090944","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:09:40Z","timestamp":1789117780000},"page":"944","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Inclusion of Curcumin in the Diet of Prepartum Cows and Its Effects on Animal Health and Production"],"prefix":"10.3390","volume":"13","author":[{"given":"Daiane da Silva","family":"dos Santos","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancia Animal, Universidade do Estado de Santa Catarina, Lages 88035-901, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5459-3823","authenticated-orcid":false,"given":"Aleksandro Schafer","family":"da Silva","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Zootecnia, UDESC, Chapec\u00f3, Rua Beloni Trombeta Zanini, 680E, Bairro Santo Ant\u00f4nio, Chapec\u00f3 89815-630, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica","family":"Scheid","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancia Animal, Universidade do Estado de Santa Catarina, Lages 88035-901, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Faculdade IELUSC, Joinville 89201-270, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9978-0454","authenticated-orcid":false,"given":"Carine","family":"De Freitas Milarch","sequence":"additional","affiliation":[{"name":"Faculdade IELUSC, Joinville 89201-270, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4850-1341","authenticated-orcid":false,"given":"Andr\u00e9","family":"Thaler Neto","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancia Animal, Universidade do Estado de Santa Catarina, Lages 88035-901, SC, Brazil"},{"name":"Departamento de Produ\u00e7\u00e3o Animal e Alimentos, Universidade do Estado de Santa Catarina (CAV), Avenida Luiz de Cam\u00f5es, 2090, Bairro Conta Dinheiro, Lages 88520-000, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.2527\/1995.7392820x","article-title":"Impact of changes in organic nutrient metabolism on feeding the transition dairy cow","volume":"73","author":"Grummer","year":"1995","journal-title":"J. Anim. Sci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3168\/jds.2017-13185","article-title":"Ethyl-cellulose rumen-protected methionine alleviates inflammation and oxidative stress and improves neutrophil function during the periparturient period and early lactation in Holstein dairy cows","volume":"101","author":"Batistel","year":"2018","journal-title":"J. Dairy Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"389","DOI":"10.15232\/aas.2019-01929","article-title":"Revis\u00e3o convidada: Quantifica\u00e7\u00e3o da mobiliza\u00e7\u00e3o de prote\u00ednas em vacas leiteiras durante o per\u00edodo de transi\u00e7\u00e3o","volume":"36","author":"Mccabe","year":"2020","journal-title":"Appl. Anim. Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"8263","DOI":"10.3168\/jds.2015-9617","article-title":"Invited review: Cessation of lactation: Effects on animal welfare","volume":"98","author":"Zobel","year":"2015","journal-title":"J. Dairy Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1017\/S175173111200170X","article-title":"Nutrition, immune function and health of dairy cattle","volume":"7","author":"Ingvartsen","year":"2013","journal-title":"Animal"},{"key":"ref_6","first-page":"1033","article-title":"Availability, storage, treatment, composition and feeding value of surplus colostrum: A review","volume":"61","author":"Andrew","year":"2001","journal-title":"J. Dairy Sci. Champaign"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s40104-020-00501-x","article-title":"Role of nutraceuticals during the transition period of dairy cows: A review","volume":"11","author":"Lopreiato","year":"2020","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.rvsc.2014.01.001","article-title":"Strategies for reduced antibiotic usage in dairy cattle farms","volume":"96","author":"Trevisi","year":"2014","journal-title":"Res. Vet. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4103\/0970-9290.49065","article-title":"Uses of turmeric in dentistry: An update","volume":"20","author":"Chaturvedi","year":"2009","journal-title":"Indian J. Dent. Res."},{"key":"ref_10","first-page":"363","article-title":"Anticancer potential of curcumin: Preclinical and clinical studies","volume":"23","author":"Aggarwal","year":"2003","journal-title":"Anticancer Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/biof.1068","article-title":"Curcumin in various cancers","volume":"39","author":"Shehzad","year":"2013","journal-title":"Biofactors"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/10408690490424702","article-title":"Biological properties of curcumin-cellular and molecular mechanisms of action","volume":"44","author":"Joe","year":"2004","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/mnfr.201000221","article-title":"Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: Relevance for anti-aging intervention","volume":"55","author":"Lima","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.micro.57.030502.090938","article-title":"Pathways of oxidative damage","volume":"57","author":"Imlay","year":"2003","journal-title":"Annu. Rev. Microbiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.radmeas.2011.05.009","article-title":"Assessment in vitro of radioprotective efficacy of curcumin and resveratrol","volume":"46","author":"Montoro","year":"2011","journal-title":"Radiat. Meas."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jtcme.2016.05.005","article-title":"Atividades biol\u00f3gicas de curcumin\u00f3ides, outras biomol\u00e9culas de a\u00e7afr\u00e3o e seus derivados\u2014Uma revis\u00e3o","volume":"7","author":"Amalraj","year":"2017","journal-title":"Rev. Med. Tradic. Complement."},{"key":"ref_17","first-page":"1149","article-title":"Vision for prehension in the medial parietal cortex","volume":"27","author":"Fattori","year":"2015","journal-title":"Cereb. Cortex"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.3382\/ps.2013-03095","article-title":"Dietary Curcuma longa enhances resistance against Eimeria maxima and Eimeria tenella infections in chickens","volume":"92","author":"Kim","year":"2013","journal-title":"Poult. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"6738","DOI":"10.1158\/1078-0432.CCR-05-0171","article-title":"Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells","volume":"11","author":"Strier","year":"2005","journal-title":"Clin. Cancer Res."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Damo, M., Wandscheer, J.G.W., Signor, M.H., Marcon, C., Nora, L., Xavier, A.C.H., Wagner, R., Vedovatto, M., and Silva, A.S.D. (2026). Curcumin as a dietary additive in early-finished feedlot steers and its effects on performance, ruminal environment, animal health, and meat quality. Animals, 16.","DOI":"10.3390\/ani16020174"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/0974-8520.146254","article-title":"Evaluation of a topical herbal drug for its in-vivo immunomodulatory effect on cytokines production and antibacterial activity in bovine subclinical mastitis","volume":"35","author":"Bhatt","year":"2014","journal-title":"Ayu"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"16","DOI":"10.17533\/udea.rccp.v33n1a02","article-title":"Dietary addition of curcumin favors weight gain and has antioxidant, anti-inflammatory and anticoccidial action in dairy calves","volume":"33","author":"Glombowsky","year":"2020","journal-title":"Rev. Colomb. Cienc. Pecu."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.anifeedsci.2018.10.010","article-title":"Addition of curcumin to the diet of dairy sheep improves health, performance and milk quality","volume":"246","author":"Jaguezeski","year":"2018","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref_24","unstructured":"AOAC (2000). Official Methods of Analysis of AOAC International, Association of Official Analytical Chemists. [17th ed.]."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.3168\/jds.S0022-0302(91)78551-2","article-title":"Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition","volume":"74","author":"Robertson","year":"1991","journal-title":"J. Dairy Sci."},{"key":"ref_26","unstructured":"Brazilian Health Regulatory Agency (ANVISA) (2019). Brazilian Pharmacopoeia."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.3168\/jds.2009-2943","article-title":"An evaluation of Brix refractometry instruments for measurement of colostrum quality in dairy cattle","volume":"93","author":"Bielmann","year":"2010","journal-title":"J. Dairy Sci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"10131","DOI":"10.3168\/jds.2020-19812","article-title":"Associations between the metabolic status of the cow and colostrum quality as determined by Brix refractometry","volume":"104","author":"Immler","year":"2021","journal-title":"J. Dairy Sci."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0891-5849(95)02043-8","article-title":"Improved analysis of malondialdehyde in human body fluids","volume":"20","author":"Jentzsch","year":"1996","journal-title":"Free Radic. Biol. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: The FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal. Biochem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0076-6879(81)77030-7","article-title":"Glutathione transferase (human placenta)","volume":"77","author":"Mannervik","year":"1981","journal-title":"Methods Enzymol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"Eur. J. Biochem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.2460\/ajvr.1998.59.10.1234","article-title":"Changes in plasma protein concentrations in ponies with experimentally induced alimentary laminitis","volume":"59","author":"Fagliari","year":"1998","journal-title":"Am. J. Vet. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/jpn.12890","article-title":"Metaphylactic effect of minerals on the immune response, biochemical variables and antioxidant status of newborn calves","volume":"102","author":"Tomasi","year":"2018","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_35","unstructured":"Dohoo, I., Martin, W., and Stryhn, H. (2009). Veterinary Epidemiologic Research, VER Inc.. [2nd ed.]."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Lora, I., Massignani, M., Stefani, A., and Gottardo, F. (2021). Potential Benefits to Dairy Cow Welfare of Using a Ceftiofur-Ketoprofen Combination Drug for the Treatment of Inflammatory Disease Associated with Pyrexia: A Field Clinical Trial on Acute Puerperal Metritis. Animals, 11.","DOI":"10.3390\/ani11061597"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e70631","DOI":"10.1002\/vms3.70631","article-title":"Variation in Uterine and Serum Proteins During the Reproductive Cycle in Dairy Cows Following Low and High Dietary Protein Intake","volume":"11","author":"Pirestani","year":"2025","journal-title":"Vet. Med. Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.2478\/aoas-2020-0100","article-title":"Effect of curcumin dietary supplementation on growth performance, physiology, carcass characteristics and meat quality in lambs","volume":"21","author":"Marcon","year":"2021","journal-title":"Ann. Anim. Sci."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.3168\/jds.2018-15386","article-title":"Associations of pre-and postpartum lying time with metabolic, inflammation, and health status of lactating dairy cows","volume":"102","author":"Menichetti","year":"2019","journal-title":"J. Dairy Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"6737","DOI":"10.3168\/jds.2016-10969","article-title":"Insulin signaling, inflammation, and lipolysis in subcutaneous adipose tissue of transition dairy cows either overfed energy during the prepartum period or fed a controlled-energy diet","volume":"99","author":"Mann","year":"2016","journal-title":"J. Dairy Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4142\/jvs.2011.12.3.251","article-title":"Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows","volume":"12","author":"Pereira","year":"2011","journal-title":"J. Vet. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/B978-0-12-370491-7.00005-2","article-title":"Proteins, proteomics, and the dysproteinemias","volume":"6","author":"Eckersall","year":"2008","journal-title":"Clin. Biochem. Domest. Anim."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"31","DOI":"10.51966\/jvas.2020.51.1.31-33","article-title":"Higher concentration of haptoglogin indicates transient inflammation and negative energy balance in transition cows","volume":"51","author":"Bhat","year":"2020","journal-title":"J. Vet. Anim. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1051\/vetres:2004002","article-title":"Application of acute phase protein measurements in veterinary clinical chemistry","volume":"35","author":"Petersen","year":"2004","journal-title":"Vet. Res."},{"key":"ref_45","unstructured":"Kaneko, J.J., Harvey, J.W., and Bruss, M.L. (2008). Clinical Biochemistry of Domestic Animals, Academic Press."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.smallrumres.2018.11.014","article-title":"Diet supplemented with curcumin for nursing lambs improves animal growth, energetic metabolism, and performance of the antioxidant and immune systems","volume":"170","author":"Molosse","year":"2019","journal-title":"Small Rumin. Res."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"998","DOI":"10.2460\/javma.250.9.998","article-title":"Bovine colostral cells\u2014The often forgotten component of colostrum","volume":"250","author":"Gonzalez","year":"2017","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_48","first-page":"1","article-title":"Mechanisms of action of immune globulin","volume":"157","author":"Alecsandru","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/jfd.12503","article-title":"Combined antiparasitic and anti-inflammatory effects of the natural polyphenol curcumin on turbot scuticociliatosis","volume":"40","author":"Mallo","year":"2017","journal-title":"J. Fish Dis."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e20201592","DOI":"10.1590\/0001-3765202220201592","article-title":"Addition of a\u00e7ai oil during the close-up dry period of Holstein cows improves colostrum quality and immune responses of their calves","volume":"94","author":"Santos","year":"2022","journal-title":"An. Acad. Bras. Cienc."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e20200149","DOI":"10.1590\/0001-3765202020200149","article-title":"Effects of the inclusion of a\u00e7ai oil in diet of prepartum Holstein cows on milk production, somatic cell counts and future lactation","volume":"92","author":"Santos","year":"2020","journal-title":"An. Acad. Bras. Cienc."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.maturitas.2011.12.009","article-title":"Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome","volume":"71","author":"Jungbauer","year":"2012","journal-title":"Maturitas"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Van Saun, R.J. (2006). Metabolic profiles for evaluation of the transition period. American Association of Bovine Practitioners Conference Proceeding, American Association of Bovine Practitioners.","DOI":"10.21423\/aabppro20064693"},{"key":"ref_54","unstructured":"Silva, P.R.L. (2009). Perfil Sangu\u00edneo de F\u00eameas Bovinas em Gesta\u00e7\u00e3o e no Periparto e Avalia\u00e7\u00e3o da Transfer\u00eancia de Imunidade Passiva aos Descendentes. [Master\u2019s Dissertation, Faculdade de Ci\u00eancias Agr\u00e1rias e Veterin\u00e1rias, Universidade Estadual Paulista]."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2754\/avb200877010051","article-title":"Acute phase proteins and variables of protein metabolism in dairy cows during the pre-and postpartal period","volume":"77","author":"Nagy","year":"2008","journal-title":"Acta Vet. Brno"},{"key":"ref_56","first-page":"102","article-title":"Serum C-reactive protein in dairy herds 102\u2013107","volume":"67","author":"Lee","year":"2003","journal-title":"Can. J. Vet. Res."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Thomas, F.C., Waterston, M., Hastie, P., Parkin, T., Haining, H., and Eckersall, P.D. (2015). The major acute phase proteins of bovine milk in a commercial dairy herd. BMC Vet. Res., 11.","DOI":"10.1186\/s12917-015-0533-3"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2478\/v10181-011-0149-x","article-title":"Concentration of serum amyloid A and ceruloplasmin activity in milk from cows with subclinical mastitis caused by different pathogens","volume":"15","author":"Szczubial","year":"2012","journal-title":"Pol. J. Vet. Sci."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.14202\/vetworld.2016.1056-1062","article-title":"Determination of ceruloplasmin, some other acute phase proteins, and biochemical parameters in cows with endometritis","volume":"9","author":"Kaya","year":"2016","journal-title":"Vet. World"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1590\/S1415-52732010000400013","article-title":"Oxidative stress: Concept, implications and modulating factors","volume":"23","author":"Barbosa","year":"2010","journal-title":"Rev. Nutr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1017\/S0022029920000813","article-title":"Colostrum from primiparous Holstein cows shows higher antioxidant activity than colostrum of multiparous ones","volume":"87","author":"Moretti","year":"2020","journal-title":"J. Dairy Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"6672","DOI":"10.3168\/jds.2019-16248","article-title":"Short communication: Pro- and antioxidative indicators in serum of dairy cows during late pregnancy and early lactation: Testing the effects of parity, different dietary energy levels, and farm","volume":"102","author":"Urh","year":"2019","journal-title":"J. Dairy Sci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"8592","DOI":"10.3168\/jds.2024-24706","article-title":"Effects of parity and week after calving on the metabolic, redox, and immune status of dairy cows","volume":"107","author":"Corset","year":"2024","journal-title":"J. Dairy Sci."}],"container-title":["Veterinary Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-7381\/13\/9\/944\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:33:26Z","timestamp":1789119206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-7381\/13\/9\/944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":63,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["vetsci13090944"],"URL":"https:\/\/doi.org\/10.3390\/vetsci13090944","relation":{},"ISSN":["2306-7381"],"issn-type":[{"value":"2306-7381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]}}}