{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:02:50Z","timestamp":1792569770837,"version":"4.5.0"},"reference-count":24,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Chronic Bee Paralysis Virus (CBPV), a widespread honey bee RNA virus, causes massive worker bee losses, mostly in strong colonies. Two different syndromes, with paralysis, ataxia and flight incapacity on one hand and black hairless individuals with shortened abdomens on the other, can affect a colony simultaneously. This case report presents two Apis mellifera carnica colonies with symptoms of paralysis and hairless black syndrome in 2019. Via RT-PCR, a highly positive result for CBPV was detected in both samples. Further problems, such as a Nosema infection and Varroa infestation, were present in these colonies. Therapy methods were applied to colony 1 comprising queen replacement, shook swarm method and Varroa control, whereas colony 2 was asphyxiated after queen loss and colony weakening. After therapy, colony 1 was wintered without symptoms. Beekeeping and sanitary measures can save a CBPV-infected colony, while further complications result in total colony loss.<\/jats:p>","DOI":"10.3390\/vetsci7030142","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T09:28:08Z","timestamp":1600853288000},"page":"142","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Overt Infection with Chronic Bee Paralysis Virus (CBPV) in Two Honey Bee Colonies"],"prefix":"10.3390","volume":"7","author":[{"given":"Julia","family":"Dittes","sequence":"first","affiliation":[{"name":"Centre for Applied Training and Learning, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 19, 04103 Leipzig, Germany"},{"name":"Institute of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 43, 04103 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc O.","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, S\u00fcdufer 10, 17493 Greifswald, Insel Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heike","family":"Aupperle-Lellbach","sequence":"additional","affiliation":[{"name":"LABOKLIN GmbH &amp; CO.KG, Labor f\u00fcr klinische Diagnostik, Steubenstra\u00dfe 4, 97688 Bad Kissingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph K. W.","family":"M\u00fclling","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 43, 04103 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilka U.","family":"Emmerich","sequence":"additional","affiliation":[{"name":"VETIDATA, Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine, Leipzig University, An den Tierkliniken 39, 04103 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1051\/apido\/2010014","article-title":"The German bee monitoring project: A long term study to understand periodically high winter losses of honey bee colonies","volume":"41","author":"Genersch","year":"2010","journal-title":"Apidologie"},{"key":"ref_2","unstructured":"Rosenkranz, P., von der Ohe, W., Sch\u00e4fer, M., Genersch, E., B\u00fcchler, R., Berg, S., and Otten, C. 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