{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:22:45Z","timestamp":1792437765086,"version":"4.5.0"},"reference-count":30,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T00:00:00Z","timestamp":1646870400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Although antibiotics have played a certain positive role in the prevention and treatment of poultry diseases, as well as the promotion of poultry growth, some farmers use antibiotics in an incorrect way in the breeding process, resulting in antibiotic residues in poultry tissues, organs and edible products. Residual antibiotics enter the human body through the food chain and accumulate, which not only causes poisoning and allergic reactions, but also drug resistance of pathogenic microorganisms, thus endangering the health of consumers. In this investigation, the residues of 24 antibiotics, including fluoroquinolones, sulfonamides, macrolides, tetracyclines, antivirals, lincomycin and florfenicol, were analyzed in 1211 poultry egg samples in Shandong, China, from 2018 to 2020. Then, based on the per capita intake of poultry eggs recommended in the dietary guidelines of Chinese residents, the maximum residue limit of veterinary drugs specified in Chinese regulations and the average weight of males and females aged 18 and over in 2020, the risk of residual antibiotics was evaluated by International Food Safety indices (IFS). The detection results showed that 104 of 1211 samples were detected with antibiotic residues, with a detection rate of 8.58%. Among them, the main residues were enrofloxacin, sulfonamides and florfenicol. The IFS calculation results showed that the IFS of residual antibiotics ranged from 1.44 \u00d7 10\u22127 to 0.102. Therefore, although enrofloxacin, sarafloxacin, danofloxacin, sulfonamides, tilmicosin, doxycycline, florfenicol, which are banned during egg laying, were detected in poultry eggs in Shandong, these residues did not pose a threat to the health of Chinese adult consumers, according to the daily dietary habits of Chinese people. However, it is strongly suggested that Shandong should strengthen the monitoring of antibiotic use during egg laying.<\/jats:p>","DOI":"10.3390\/vetsci9030126","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T20:19:10Z","timestamp":1646943550000},"page":"126","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Risk Analysis of 24 Residual Antibiotics in Poultry Eggs in Shandong, China (2018\u20132020)"],"prefix":"10.3390","volume":"9","author":[{"given":"Xiaoyu","family":"Ma","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Chen","sequence":"additional","affiliation":[{"name":"Shandong Center for Quality Control of Feed and Veterinary Drugs, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Yin","sequence":"additional","affiliation":[{"name":"Shandong Center for Quality Control of Feed and Veterinary Drugs, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youzhi","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Center for Quality Control of Feed and Veterinary Drugs, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzhen","family":"Yang","sequence":"additional","affiliation":[{"name":"Shandong Provincial Center for Quality and Safety of Animal Products, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiguo","family":"Yang","sequence":"additional","affiliation":[{"name":"Shandong Provincial Center for Quality and Safety of Animal Products, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihua","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Provincial Center for Quality and Safety of Animal Products, Jinan 250010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Shan","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,10]]},"reference":[{"key":"ref_1","unstructured":"Ministry of Agriculture and Rural Affairs of the Peoples Republic of China (2019). 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