{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:44:13Z","timestamp":1760229853665,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>Myasthenia gravis (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a trigger for MG occurrence, and in a limited number of reports, infection with SARS-CoV-2 was found to be associated with MG expression in humans. In this report, we describe case of seronegative generalized MG in a 2-year-old crossbred female dog associated with SARS-CoV-2 infection due to close exposure to an infected owner.<\/jats:p>","DOI":"10.3390\/vetsci9070318","type":"journal-article","created":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T22:50:23Z","timestamp":1656283823000},"page":"318","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Seronegative Myasthenia Gravis with Concomitant SARS-CoV-2 Infection in a Dog"],"prefix":"10.3390","volume":"9","author":[{"given":"Mihai","family":"Musteata","sequence":"first","affiliation":[{"name":"Neurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis-Gabriel","family":"Borcea","sequence":"additional","affiliation":[{"name":"Neurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreea","family":"Despa","sequence":"additional","affiliation":[{"name":"Neurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raluca","family":"\u0218tef\u0103nescu","sequence":"additional","affiliation":[{"name":"Neurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larisa","family":"Iv\u0103nescu","sequence":"additional","affiliation":[{"name":"Parasitology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lumini\u021ba Diana","family":"Hri\u021bcu","sequence":"additional","affiliation":[{"name":"Internal Medicine Clinic, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7054-4650","authenticated-orcid":false,"given":"Radu Andrei","family":"Baisan","sequence":"additional","affiliation":[{"name":"Radiology Unit, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu","family":"L\u0103c\u0103tu\u0219","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3067-9574","authenticated-orcid":false,"given":"Gheorghe","family":"Solcan","sequence":"additional","affiliation":[{"name":"Internal Medicine Clinic, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Ia\u0219i University of Life Sciences, 700489 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1111\/jvim.15855","article-title":"Classification of Myasthenia Gravis and Congenital Myasthenic Syndromes in Dogs and Cats","volume":"34","author":"Mignan","year":"2020","journal-title":"J. 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