{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:12:01Z","timestamp":1760231521012,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T00:00:00Z","timestamp":1663891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Sciences"],"abstract":"<jats:p>A 5-year-old recently castrated male Doberman dog presented for prolonged erection of one week\u2019s duration with associated pain and dysuria. This was the fourth episode within a year. Each episode was associated with an unusual event, which was stressful for the dog. Castration performed two months prior to the final episode did not prevent recurrence. Due to tissue necrosis, penile amputation and urethrostomy had to be performed. The dog recovered fully. Prolonged erection that persists beyond or that is unrelated to sexual stimulation is called \u201cpriapism\u201d. This term refers to the Greek god Priapus, a god of fertility, memorialized in sculptures for his giant phallus. In humans, depending on the mechanism involved, priapism is classified as nonischemic or ischemic. Because prognosis and treatment are different, priapism must be determined to be nonischemic or ischemic. Nonischemic priapism is a rare condition observed when an increase in penile arterial blood flow overwhelms the capacity of venous drainage; it is often associated with penile trauma, and does not require medical intervention. Ischemic priapism is associated with decreased venous return. In humans, ischemic priapism accounts for 95% of cases, the majority of which are idiopathic. Ischemic priapism is a urological emergency; simple conservative measures such as aspiration of blood from the corpora cavernosa and intracavernosal injection of an adrenergic agent are often successful. Stuttering priapism, also called recurrent or intermittent priapism, is a particular form of ischemic priapism reported in humans that is characterized by repetitive episodes of prolonged erections. Management consists of treating each new episode as an episode of acute ischemic priapism, and preventing recurrence with oral medications such as dutasteride and\/or baclofen, gabapentin, or tadalafil. To the authors\u2019 knowledge, this case is the first report of stuttering priapism in a dog.<\/jats:p>","DOI":"10.3390\/vetsci9100518","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T04:07:07Z","timestamp":1663906027000},"page":"518","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stuttering Priapism in a Dog\u2014First Report"],"prefix":"10.3390","volume":"9","author":[{"given":"Fran\u00e7oise A.","family":"Roux","sequence":"first","affiliation":[{"name":"Emergency and Critical Care Unit, Oniris, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, La Chantrerie, CS 40706, CEDEX 03, 44307 Nantes, France"},{"name":"Nutrition, PathoPhysiology and Pharmacology (NP3) Unit, Oniris, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, La Chantrerie, CS 40706, CEDEX 03, 44307 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Le Breuil","sequence":"additional","affiliation":[{"name":"Emergency and Critical Care Unit, Oniris, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, La Chantrerie, CS 40706, CEDEX 03, 44307 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8460-9352","authenticated-orcid":false,"given":"Julien","family":"Branchereau","sequence":"additional","affiliation":[{"name":"Institut de Transplantation-Urologie-N\u00e9phrologie, CHU de Nantes, 30 boulevard Jean Monnet, CEDEX 01, 44093 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3363-7457","authenticated-orcid":false,"given":"Jack-Yves","family":"Deschamps","sequence":"additional","affiliation":[{"name":"Emergency and Critical Care Unit, Oniris, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, La Chantrerie, CS 40706, CEDEX 03, 44307 Nantes, France"},{"name":"Nutrition, PathoPhysiology and Pharmacology (NP3) Unit, Oniris, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, La Chantrerie, CS 40706, CEDEX 03, 44307 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1097\/01.ju.0000087608.07371.ca","article-title":"American Urological Association guideline on the management of priapism","volume":"170","author":"Montague","year":"2003","journal-title":"J. Urol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1177\/1756287214542096","article-title":"Management of priapism: An update for clinicians","volume":"6","author":"Levey","year":"2014","journal-title":"Ther. Adv. Urol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.2460\/javma.1999.214.10.1483","article-title":"Theriogenology question of the month. Priapism or paraphimosis","volume":"214","author":"Kustritz","year":"1999","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S0093-691X(01)00622-7","article-title":"Priapism: A review","volume":"56","author":"Rochat","year":"2001","journal-title":"Theriogenology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1053\/j.tcam.2008.11.001","article-title":"Priapism in dogs","volume":"24","author":"Lavely","year":"2009","journal-title":"Top Companion Anim. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5213\/inj.2014.18.2.58","article-title":"Clinical neuroanatomy and neurotransmitter-mediated regulation of penile erection","volume":"18","author":"Jung","year":"2014","journal-title":"Int. Neurourol. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1590\/S1677-55382003000500002","article-title":"Priapism\u2014Etiology, pathophysiology and management","volume":"29","author":"Stuebinger","year":"2003","journal-title":"Int. Braz. J. Urol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.2042-3306.1978.tb02227.x","article-title":"Priapism after sedation, neuroleptanalgesia and anaesthesia in the horse","volume":"10","author":"Pearson","year":"1978","journal-title":"Equine. Vet. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1136\/vr.109.3.64-a","article-title":"Priapism and ACP in the horse","volume":"109","author":"Gerring","year":"1981","journal-title":"Vet. Rec."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1532-950X.1987.tb00937.x","article-title":"Surgical treatment of priapism in a stallion","volume":"16","author":"Schumacher","year":"1987","journal-title":"Vet. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.2460\/javma.1991.198.06.1043","article-title":"Priapism in a stallion with generalized malignant melanoma","volume":"198","author":"Blanchard","year":"1991","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2460\/javma.1991.199.09.1183","article-title":"Pharmacologic treatment of priapism in two horses","volume":"199","author":"Wilson","year":"1991","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1751-0813.1999.tb11226.x","article-title":"Partial phallectomy to treat priapism in a horse","volume":"77","author":"Gaughan","year":"1999","journal-title":"Aust. Vet. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1292\/jvms1939.51.1227","article-title":"Surgical treatment of priapism observed in a dog and a cat","volume":"51","author":"Orima","year":"1989","journal-title":"Nihon Juigaku Zasshi. Jpn. J. Vet. Sci."},{"key":"ref_15","first-page":"963","article-title":"Priapism after castration in a cat","volume":"195","author":"Swalec","year":"1989","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1748-5827.1995.tb02912.x","article-title":"Priapism in seven cats","volume":"36","author":"Brown","year":"1995","journal-title":"J. Small Anim. Pract."},{"doi-asserted-by":"crossref","unstructured":"Lee, J.M., Sung, A.W., Lee, H.J., Song, J.H., and Song, K.H. (2022). Presumptive Non-Ischemic Priapism in a Cat. Vet. Sci., 9.","key":"ref_17","DOI":"10.3390\/vetsci9010029"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/2305-0500.220985","article-title":"Non-ischemic priapism in dog: Case report","volume":"7","year":"2018","journal-title":"Asian Pac. J. Reprod."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"90","DOI":"10.2460\/javma.1990.197.01.90","article-title":"Fecal incontinence, urinary incontinence, and priapism associated with multifocal distemper encephalomyelitis in a dog","volume":"197","author":"Guilford","year":"1990","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"ref_20","first-page":"e58","article-title":"Priapism associated with lumbar stenosis in a dog","volume":"48","author":"Colaco","year":"2013","journal-title":"Reprod. Domest. Anim."},{"key":"ref_21","first-page":"558","article-title":"Priapism secondary to perineal abscess in a dog\u2014A case report","volume":"45","author":"Santos","year":"2008","journal-title":"Reprod Domest Anim."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1136\/vr.100039","article-title":"Penile amputation and scrotal urethrostomy in 18 dogs","volume":"169","author":"Burrow","year":"2011","journal-title":"Vet. Rec."},{"key":"ref_23","first-page":"547","article-title":"Priapism secondary to penile metastasis in a dog","volume":"43","author":"Rogers","year":"2002","journal-title":"Can. Vet. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"218","DOI":"10.17555\/jvc.2017.06.34.3.218","article-title":"Idiopathic Ischemic Priapism in a Shih Tzu","volume":"34","author":"Park","year":"2017","journal-title":"J. Vet. Clin. Korean Soc. Vet. Clin."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ucl.2007.08.006","article-title":"Priapism: Current principles and practice","volume":"34","author":"Burnett","year":"2007","journal-title":"Urol. Clin. North Am."},{"key":"ref_26","first-page":"56","article-title":"Diagnostic and therapeutic options for the management of ischemic and nonischemic priapism","volume":"12","author":"Bassett","year":"2010","journal-title":"Rev. Urol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1111\/j.1743-6109.2009.01625.x","article-title":"Priapism: Pathogenesis, epidemiology, and management","volume":"7","author":"Broderick","year":"2010","journal-title":"J. Sex. Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5152\/tud.2017.59458","article-title":"Ischaemic priapism: A clinical review","volume":"43","author":"Ridgley","year":"2017","journal-title":"Turk. J. Urol."},{"doi-asserted-by":"crossref","unstructured":"Schifano, N., Capogrosso, P., Boeri, L., Fallara, G., Cakir, O.O., Castiglione, F., Alnajjar, H.M., Muneer, A., Deho, F., and Schifano, F. (2022). Medications mostly associated with priapism events: Assessment of the 2015\u20132020 Food and Drug Administration (FDA) pharmacovigilance database entries. Int. J. Impot. Res.","key":"ref_29","DOI":"10.1016\/S2666-1683(21)00721-7"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"173","DOI":"10.23736\/S0393-2249.19.03323-X","article-title":"The management of stuttering priapism","volume":"72","author":"Liguori","year":"2020","journal-title":"Minerva Urol. Nefrol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.eururo.2013.11.008","article-title":"European Association of Urology guidelines on priapism","volume":"65","author":"Salonia","year":"2014","journal-title":"Eur. Urol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1097\/JU.0000000000002236","article-title":"Acute Ischemic Priapism: An AUA\/SMSNA Guideline","volume":"206","author":"Bivalacqua","year":"2021","journal-title":"J. Urol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"237","DOI":"10.4081\/aiua.2022.2.237","article-title":"An update on the management algorithms of priapism during the last decade","volume":"94","author":"Moussa","year":"2022","journal-title":"Arch. Ital. Urol. Androl."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s11934-022-01096-8","article-title":"Review of Ischemic and Non-ischemic Priapism","volume":"23","author":"Biebel","year":"2022","journal-title":"Curr. Urol. Rep."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.ucl.2021.07.003","article-title":"Management of Priapism: 2021 Update","volume":"48","author":"Ericson","year":"2021","journal-title":"Urol. Clin. North Am."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1745-7262.2008.00314.x","article-title":"Insights of priapism mechanism and rationale treatment for recurrent priapism","volume":"10","author":"Yuan","year":"2008","journal-title":"Asian J. Androl."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/bju.15370","article-title":"Medical treatment of recurrent ischaemic priapism: A review of current molecular therapeutics and a new clinical management paradigm","volume":"127","author":"Joice","year":"2021","journal-title":"BJU Int."},{"unstructured":"Abdeen, B.M., and Leslie, S.W. (2022). Stuttering Priapism. StatPearls, StatPearls Publishing.","key":"ref_38"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s11934-012-0258-9","article-title":"Stuttering priapism: Insights into pathogenesis and management","volume":"13","author":"Morrison","year":"2012","journal-title":"Curr. Urol. Rep."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1001\/archinte.1980.00330220022011","article-title":"Priapism and impotence in homozygous sickle cell disease","volume":"140","author":"Emond","year":"1980","journal-title":"Arch. Intern. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1111\/j.1464-410X.2011.10367.x","article-title":"Treating stuttering priapism","volume":"108","author":"Kheirandish","year":"2011","journal-title":"BJU Int."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/aja.2011.114","article-title":"Medical management of ischemic stuttering priapism: A contemporary review of the literature","volume":"14","author":"Levey","year":"2012","journal-title":"Asian J. Androl."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"87","DOI":"10.21037\/tau.2019.07.15","article-title":"Dutasteride in the long-term management of stuttering priapism","volume":"9","author":"Baker","year":"2020","journal-title":"Transl. Androl. Urol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1111\/j.1743-6109.2009.01246.x","article-title":"Anxiety disorders in patients with idiopathic priapism: Risk factor and pathophysiologic link?","volume":"6","author":"Burnett","year":"2009","journal-title":"J. Sex. Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1016\/S0022-5347(05)64201-2","article-title":"Treatment of recurrent idiopathic priapism with oral baclofen","volume":"168","author":"Rourke","year":"2002","journal-title":"J. Urol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/sj.sc.3101547","article-title":"Management of recurrent priapism in a cervical spinal cord injury patient with oral baclofen therapy","volume":"42","author":"Vaidyanathan","year":"2004","journal-title":"Spinal Cord."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jpurol.2005.11.009","article-title":"Recurrent priapism in the young patient treated with baclofen","volume":"2","author":"Moreira","year":"2006","journal-title":"J. Pediatr. Urol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.jsxm.2020.11.010","article-title":"Rare Disorders of Painful Erection: A Cohort Study of the Investigation and Management of Stuttering Priapism and Sleep-Related Painful Erection","volume":"18","author":"Johnson","year":"2021","journal-title":"J. Sex. Med."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0090-4295(93)90338-B","article-title":"Placebo-controlled study of oral terbutaline and pseudoephedrine in management of prostaglandin E1-induced prolonged erections","volume":"42","author":"Lowe","year":"1993","journal-title":"Urology"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/and.12438","article-title":"Idiopathic stuttering priapism treated with salbutamol orally: A case report","volume":"48","author":"Migliorini","year":"2016","journal-title":"Andrologia"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/sj.ijir.3901165","article-title":"Gabapentin in the management of the recurrent, refractory, idiopathic priapism","volume":"16","author":"Perimenis","year":"2004","journal-title":"Int. J. Impot. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.urology.2005.11.045","article-title":"Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism","volume":"67","author":"Burnett","year":"2006","journal-title":"Urology"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1590\/1806-9282.63.08.689","article-title":"Daily use of phosphodiesterase type 5 inhibitors as prevention for recurrent priapism","volume":"63","author":"Nardozza","year":"2017","journal-title":"Rev. Assoc. Med. Bras. (1992)"},{"doi-asserted-by":"crossref","unstructured":"Massenio, P., D\u2019Altilia, N., Sanguedolce, F., Carrieri, G., and Cormio, L. (2018). Daily tadalafil for the chronic phase of stuttering priapism: A case report. 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