{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T02:08:27Z","timestamp":1774318107638,"version":"3.50.1"},"reference-count":55,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision"],"abstract":"<jats:p>Evaluate the effect of corneal thickness, densitometry and curvature on intraocular pressure (IOP) measurements obtained by Goldmann applanation tonometry (GAT), non-contact tonometry (NCT), rebound tonometry (RT), and dynamic contour tonometry (DCT). A cross-sectional prospective study involving 40 participants was performed. Corneal measurements were obtained using Pentacam (Oculus GMbH, Wetzlar, Germany), densitometry was measured at annuli of 0\u20132, 2\u20136, 6\u201310 and 10\u201312 mm. The relationship between corneal thickness (central, 4 and 6 mm), corneal astigmatism and corneal densitometry and IOP was examined. There was a significant relationship between corneal thickness (central, 4 and 6 mm) and GAT180, GAT90, RT, and NCT (P &lt; 0.001 for all comparisons) but not for DCT. Higher corneal densitometry (6\u201310 mm and 10\u201312 mm zones) was associated with higher IOP from GAT180 and GAT90, and higher densitometry in the 6\u201310 mm zone correlated with higher IOP from NCT, however corneal densitometry increased with age. Accounting for age, the relationship between corneal densitometry and IOP measurements was not significant. In eyes with greater corneal astigmatism there was a greater difference between GAT90 and GAT180 measurements. IOP measurements may be affected by corneal thickness, densitometry and curvature. DCT was less affected by properties of the cornea compared to other devices.<\/jats:p>","DOI":"10.3390\/vision4040045","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T10:14:22Z","timestamp":1603275262000},"page":"45","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Effect of Corneal Thickness, Densitometry and Curvature on Intraocular Pressure Measurements Obtained by Applanation, Rebound and Dynamic Contour Tonometry"],"prefix":"10.3390","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6365-1957","authenticated-orcid":false,"given":"Marco Antonio de Castro","family":"Olyntho Junior","sequence":"first","affiliation":[{"name":"Olyntho Oftalmo.center, 15091-751 S\u00e3o Jos\u00e9 do Rio Preto, S\u00e3o Paulo, Brazil"},{"name":"University of Edinburgh, Edinburgh EH8 9YL, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Bertazzi","family":"Augusto","sequence":"additional","affiliation":[{"name":"Olyntho Oftalmo.center, 15091-751 S\u00e3o Jos\u00e9 do Rio Preto, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina P. B.","family":"Gracitelli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Federal University of S\u00e3o Paulo, 13565-905 S\u00e3o Paulo, Brazil"},{"name":"Centro de Estudos Alcides Hirai, Ver Mais Oftalmologia, 07750-000 Vinhedo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Tatham","sequence":"additional","affiliation":[{"name":"University of Edinburgh, Edinburgh EH8 9YL, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/IJG.0000000000000359","article-title":"Clinical Evaluation of Methods to Correct Intraocular Pressure Measurements by the Goldmann Applanation Tonometer, Ocular Response Analyzer, and Corvis ST Tonometer for the Effects of Corneal Stiffness Parameters","volume":"25","author":"Bao","year":"2016","journal-title":"J. Glaucoma"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1136\/bjophthalmol-2015-307674","article-title":"Evaluation of a new rebound tonometer for self-measurement of intraocular pressure","volume":"100","author":"Dabasia","year":"2016","journal-title":"Br. J. Ophthalmol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.ophtha.2004.06.013","article-title":"Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans, and Japanese in a glaucoma clinic","volume":"111","author":"Aghaian","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/IJG.0000000000000501","article-title":"Corneal densitometry: A new technique for objective assessment of corneal clarity in Pseudoexfoliation syndrome","volume":"25","author":"Sekeroglu","year":"2016","journal-title":"J. Glaucoma"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.2147\/OPTH.S115203","article-title":"Comparison of Goldmann applanation tonometry and Pascal dynamic contour tonometry in relation to central corneal thickness and corneal curvature","volume":"10","author":"Andreanos","year":"2016","journal-title":"Clin. Ophthalmol. (Auckl. N.Z.)"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.clae.2014.11.001","article-title":"Comparison between Corvis and other tonometers in healthy eyes","volume":"38","author":"Lanza","year":"2015","journal-title":"Contact Lens Anterior Eye J. Br. Contact Lens Assoc."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"132","DOI":"10.4103\/0301-4738.179723","article-title":"Can higher end tonometers be used interchangeably in routine clinical practice?","volume":"64","author":"Patel","year":"2016","journal-title":"Indian J. Ophthalmol."},{"key":"ref_9","first-page":"1521","article-title":"Dependence of dynamic contour and Goldmann applanation tonometries on peripheral corneal thickness","volume":"10","author":"Janez","year":"2017","journal-title":"Int. J. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1136\/bjo.2003.019331","article-title":"Effect of corneal parameters on measurements using the pulsatile ocular blood flow tonograph and Goldmann applanation tonometer","volume":"88","author":"Gunvant","year":"2004","journal-title":"Br. J. Ophthalmol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3921\/joptom.2008.43","article-title":"Modalities of Tonometry and their Accuracy with Respect to Corneal Thickness and Irregularities","volume":"1","author":"Prata","year":"2008","journal-title":"J. Optom."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/bs.pbr.2015.06.003","article-title":"New technologies for measuring intraocular pressure","volume":"Volume 221","year":"2015","journal-title":"Progress in Brain Research"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1590\/S0004-27492013000600007","article-title":"Correlations between different tonometries and ocular biometric parameters in patients with primary congenital glaucoma","volume":"76","author":"Mendes","year":"2013","journal-title":"Arq. Bras. De Oftalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1159\/000441796","article-title":"Review on Dynamic Contour Tonometry and Ocular Pulse Amplitude","volume":"55","author":"Willekens","year":"2015","journal-title":"Ophthalmic Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/01.ijg.0000176936.16015.4e","article-title":"Dynamic contour tonometry: Presentation of a new tonometer","volume":"14","author":"Kanngiesser","year":"2005","journal-title":"J. Glaucoma"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.jfo.2016.09.009","article-title":"Intraocular pressure measurement after DSAEK by iCare, Goldmann applanation and dynamic contour tonometry: A comparative study","volume":"39","author":"Achiron","year":"2016","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1097\/OPX.0000000000001120","article-title":"Tonometry after Intrastromal Corneal Ring Segments for Keratoconus","volume":"94","year":"2017","journal-title":"Optom. Vis. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/01.ijg.0000169393.40298.05","article-title":"Comparison of dynamic contour tonometry with goldman applanation tonometry over a wide range of central corneal thickness","volume":"14","author":"Doyle","year":"2005","journal-title":"J. Glaucoma"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1055\/s-2004-812895","article-title":"Dynamic contour tonometry for post-LASIK intraocular pressure measurements","volume":"221","author":"Duba","year":"2004","journal-title":"Klin. Mon. Augenheilkd."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1167\/iovs.04-0018","article-title":"Comparison of dynamic contour tonometry with goldmann applanation tonometry","volume":"45","author":"Kaufmann","year":"2004","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.joco.2016.08.010","article-title":"Comparison of current tonometry techniques in measurement of intraocular pressure","volume":"29","author":"Kouchaki","year":"2017","journal-title":"J. Curr. Ophthalmol."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Lanza, M., Rinaldi, M., Carnevale, U.A.G., di Staso, S., Sconocchia, M.B., and Costagliola, C. (2018). Analysis of differences in intraocular pressure evaluation performed with contact and non-contact devices. BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0900-5"},{"key":"ref_23","first-page":"299","article-title":"Comparison of Goldmann applanation tonometry, rebound tonometry and dynamic contour tonometry in normal and glaucomatous eyes","volume":"8","author":"Ozcura","year":"2015","journal-title":"Int. J. Ophthalmol."},{"key":"ref_24","first-page":"1107","article-title":"Comparison of dynamic contour tonometry versus Goldmann applanation tonometry according to the International Ocular Tonometer Standards ISO 8612 in glaucoma patients","volume":"231","author":"Pahlitzsch","year":"2014","journal-title":"Klin. Mon. Augenheilkd."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e419","DOI":"10.1097\/IJG.0000000000000338","article-title":"Effect of Laser in Situ Keratomileusis on Schiotz, Goldmann, and Dynamic Contour Tonometric Measurements","volume":"25","author":"Pinero","year":"2016","journal-title":"J. Glaucoma"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.jcrs.2003.12.033","article-title":"Assessment of the Pascal dynamic contour tonometer in monitoring intraocular pressure in unoperated eyes and eyes after LASIK","volume":"30","author":"Siganos","year":"2004","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"815","DOI":"10.4103\/0301-4738.171956","article-title":"A cross-sectional study to compare intraocular pressure measurement by sequential use of Goldman applanation tonometry, dynamic contour tonometry, ocular response analyzer, and Corvis ST","volume":"63","author":"Tejwani","year":"2015","journal-title":"Indian J. Ophthalmol."},{"key":"ref_28","first-page":"1190","article-title":"Dynamic Contour Tonometry and Goldmann Applanation Tonometry: Difference of Intraocular Pressure Values Between Eyes with and without Glaucomatous Damage in Thin Corneas","volume":"232","author":"Akkan","year":"2015","journal-title":"Klin. Mon. Augenheilkd."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s10792-017-0518-2","article-title":"Agreement among Goldmann applanation tonometer, iCare, and Icare PRO rebound tonometers; non-contact tonometer; and Tonopen XL in healthy elderly subjects","volume":"38","author":"Kato","year":"2018","journal-title":"Int. Ophthalmol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1007\/s00417-017-3725-7","article-title":"Limbal rebound tonometry: Clinical comparisons and applications","volume":"255","author":"Bontzos","year":"2017","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.3892\/etm.2017.4164","article-title":"Comparison of the iCare rebound tonometer and the Goldmann applanation tonometer","volume":"13","author":"Gao","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.optom.2017.11.003","article-title":"Reply to comment by De Bernardo and Rosa on \u201cEvaluation of Goldmann applanation tonometry, rebound tonometry and dynamic contour tonometry in keratoconus\u201c","volume":"11","author":"Ozcura","year":"2018","journal-title":"J. Optom."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.jcrs.2005.02.021","article-title":"Assessment of Pascal dynamic contour tonometer in monitoring IOP after LASIK","volume":"31","author":"Kniestedt","year":"2005","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1001\/jamaophthalmol.2017.1035","article-title":"Stop \u201cadjusting\u201d intraocular pressure measurements","volume":"135","author":"Brandt","year":"2017","journal-title":"JAMA Ophthalmol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0039-6257(00)00110-7","article-title":"Human corneal thickness and its impact on intraocular pressure measures: A review and meta-analysis approach","volume":"44","author":"Doughty","year":"2000","journal-title":"Surv. Ophthalmol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1097\/IJG.0000000000000674","article-title":"Evaluation of a New Rebound Self-tonometer, Icare HOME: Comparison With Goldmann Applanation Tonometer","volume":"26","author":"Takagi","year":"2017","journal-title":"J. Glaucoma"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000381781","article-title":"Comparability of Icare Pro Rebound Tonometer with Goldmann Applanation and Noncontact Tonometer in a Wide Range of Intraocular Pressure and Central Corneal Thickness","volume":"54","author":"Tamcelik","year":"2015","journal-title":"Ophthalmic Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/ICO.0000000000000374","article-title":"Measuring intraocular pressure after intrastromal corneal ring segment implantation with rebound tonometry and Goldmann applanation tonometry","volume":"34","year":"2015","journal-title":"Cornea"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/IJG.0000000000000948","article-title":"The Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements Using a Rebound Self-tonometer","volume":"27","author":"Brown","year":"2018","journal-title":"J. Glaucoma"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.optom.2017.10.001","article-title":"Evaluation of Goldmann applanation tonometry, rebound tonometry and dynamic contour tonometry in keratoconus","volume":"11","author":"Rosa","year":"2018","journal-title":"J. Optom."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.ajo.2015.07.029","article-title":"Comparison of Intraocular Pressure Measurements Obtained by Rebound, Noncontact, and Goldmann Applanation Tonometry in Children","volume":"160","author":"Feng","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.jaapos.2015.08.009","article-title":"Comparison of the Icare rebound tonometry with the Goldmann applanation tonometry in a pediatric population","volume":"19","author":"Grigorian","year":"2015","journal-title":"J. AAPOS"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ajo.2015.12.012","article-title":"Comparison of Intraocular Pressure Measurements Obtained by Rebound, Noncontact, and Goldmann Applanation Tonometry in Children","volume":"163","author":"Vodencarevic","year":"2016","journal-title":"Am. J. Ophthalmol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"788","DOI":"10.3928\/1081597X-20160720-02","article-title":"Corneal Scheimpflug Densitometry Following Photorefractive Keratectomy in Myopic Eyes","volume":"32","author":"Dariel","year":"2016","journal-title":"J. Refract. Surg. (Thorofare N.J. 1995)"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Dong, J., Zhang, Y., Zhang, H., Jia, Z., Zhang, S., Sun, B., Han, Y., and Wang, X. (2018). Corneal densitometry in high myopia. BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0851-x"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1167\/iovs.13-13236","article-title":"Normative values for corneal densitometry analysis by Scheimpflug optical assessment","volume":"55","author":"Rozema","year":"2014","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/ICU.0b013e3281ca7121","article-title":"Measuring the cornea: The latest developments in corneal topography","volume":"18","author":"Swartz","year":"2007","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1442-9071.2009.02018.x","article-title":"Photography of the anterior eye segment according to Scheimpflug\u2019s principle: Options and limitations\u2014A review","volume":"37","author":"Wegener","year":"2009","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5301\/ejo.5000644","article-title":"Quantitative assessment of corneal clarity in keratoconus: A case control study of corneal densitometry","volume":"26","author":"Anayol","year":"2016","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1097\/ICO.0000000000000266","article-title":"Corneal densitometry in keratoconus","volume":"33","author":"Lopes","year":"2014","journal-title":"Cornea"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s10792-016-0397-y","article-title":"Corneal densitometry and its correlation with age, pachymetry, corneal curvature, and refraction","volume":"37","author":"Garzon","year":"2017","journal-title":"Int. Ophthalmol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.clae.2004.08.001","article-title":"Grading of corneal transparency","volume":"27","author":"Wolffsohn","year":"2004","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ophtha.2011.08.024","article-title":"Corneal densitometry as an indicator of corneal health","volume":"119","author":"Otri","year":"2012","journal-title":"Ophthalmology"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1097\/ICO.0b013e318275e7a6","article-title":"The Effect of Anesthetic Eye Drop Instillation on the Distribution of Corneal Thickness","volume":"32","year":"2013","journal-title":"Cornea"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1097\/OPX.0b013e3182114303","article-title":"Effect of Oxybuprocaine Eye Drops on Corneal Volume and Thickness Measurements","volume":"88","author":"Rosa","year":"2011","journal-title":"Optom. Vis. Sci."}],"container-title":["Vision"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2411-5150\/4\/4\/45\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:25:33Z","timestamp":1760178333000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2411-5150\/4\/4\/45"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,21]]},"references-count":55,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,12]]}},"alternative-id":["vision4040045"],"URL":"https:\/\/doi.org\/10.3390\/vision4040045","relation":{},"ISSN":["2411-5150"],"issn-type":[{"value":"2411-5150","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,21]]}}}