{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T22:41:50Z","timestamp":1784846510934,"version":"3.55.0"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T00:00:00Z","timestamp":1623024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision"],"abstract":"<jats:p>The objective of this study was to characterize saccades in children with neurodevelopmental disorders (NDDG, 17 children, age: 7\u201312 years) and compare them with a control group (CG, 15 children, age: 7\u201312 years), comparing the outcomes obtained with a subjective score system (Northeastern State University College of Optometry\u2019s Oculomotor test, NSUCO) with the objective analysis obtained through a commercially available Eye Tracker (Tobii Eye X, Tobii, Stockholm, Sweden) and a specialized software analysis (Thomson Software Solutions, Welham Green, UK). Children from the NDDG obtained significantly lower NSUCO scores (p &lt; 0.001) compared with CG. Concerning eye tracking analyses, we found a significantly higher number of hypometric saccades in NDGG (p \u2264 0.044). Likewise, we found a significantly higher percentage of regressions in the NDDG for a time interval of presentation of stimuli of 1 s (p = 0.012). Significant correlations were found between different NSUCO scores and percentage of regressions, number of saccades completed and number of hypometric saccades. The presence of hypometric saccades and regressions seems to be a differential characteristic sign of children with neurodevelopmental disorders that can be detected using an objective eye tracking analysis, but also using the subjective test NSUCO that can be easily implemented in all clinical settings.<\/jats:p>","DOI":"10.3390\/vision5020028","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T22:23:00Z","timestamp":1623104580000},"page":"28","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Objective and Subjective Evaluation of Saccadic Eye Movements in Healthy Children and Children with Neurodevelopmental Disorders: A Pilot Study"],"prefix":"10.3390","volume":"5","author":[{"given":"Carmen","family":"Bilbao","sequence":"first","affiliation":[{"name":"Department of Optometry, Policl\u00ednica Alto Arag\u00f3n, 22003 Huesca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1546-4807","authenticated-orcid":false,"given":"David P.","family":"Pi\u00f1ero","sequence":"additional","affiliation":[{"name":"Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente de Raspeig-Alicante, Spain"},{"name":"Department of Ophtalmology, Vithas Medimar International Hospital, 03016 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1152\/ajplegacy.1903.8.4.307","article-title":"Five types of eye movement in the horizontal meridian plane of the field of regard","volume":"8","author":"Dodge","year":"1903","journal-title":"Am. J. Physiol. Content"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1196\/annals.1303.004","article-title":"Shared brainstem pathways for saccades and smooth-pursuit eye movements","volume":"1004","author":"Keller","year":"2003","journal-title":"Ann. N. Acad. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"568","DOI":"10.3389\/fnhum.2014.00568","article-title":"The influence of expertise on brain activation of the action observation network during anticipation of tennis and volleyball serves","volume":"8","author":"Balser","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1055\/s-0038-1666818","article-title":"Oculomotor assessment in children","volume":"39","author":"Doettl","year":"2018","journal-title":"Semin. Hear."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/nrneurol.2012.273","article-title":"Eye movements in patients with neurodegenerative disorders","volume":"9","author":"Anderson","year":"2013","journal-title":"Nat. Rev. Neurol."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Seassau, M., and Bucci, M.P. (2013). Reading and visual search: A developmental study in normal children. PLoS ONE, 8.","DOI":"10.3389\/fnint.2014.00085"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.preteyeres.2006.01.002","article-title":"Eye movements and the control of actions in everyday life","volume":"25","author":"Land","year":"2006","journal-title":"Prog. Retin. Eye Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00431-019-03562-x","article-title":"Are early visual behavior impairments involved in the onset of autism spectrum disorders? Insights for early diagnosis and intervention","volume":"179","author":"Apicella","year":"2020","journal-title":"Eur. J. Pediatr."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/08820538.2020.1744671","article-title":"Binocular, accommodative and oculomotor alterations in multiple sclerosis: A review","volume":"35","year":"2020","journal-title":"Semin. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Bilbao, C., and Pi\u00f1ero, D.P. (2021). Distribution of visual and oculomotor alterations in a clinical population of children with and without neurodevelopmental disorders. Brain Sci., 11.","DOI":"10.3390\/brainsci11030351"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Bilbao, C., and Pi\u00f1ero, D.P. (2020). Clinical characterization of oculomotricity in children with and without specific learning disorders. Brain Sci., 10.","DOI":"10.3390\/brainsci10110836"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00417-007-0723-1","article-title":"Poor binocular coordination of saccades in dyslexic children","volume":"246","author":"Bucci","year":"2008","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/CHI.0b013e3181a565f1","article-title":"Oculomotor anomalies in attention-deficit\/hyperactivity disorder: Evidence for deficits in response preparation and inhibition","volume":"48","author":"Mahone","year":"2009","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e12501","DOI":"10.1111\/desc.12501","article-title":"Oculomotor atypicalities developmental coordination disorder","volume":"21","author":"Sumner","year":"2018","journal-title":"Dev. Sci."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM-5), American Psychiatric Association. [5th ed.].","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref_16","first-page":"143","article-title":"Northeastern State University College of Optometry\u2019s oculomotor norms","volume":"3","author":"Maples","year":"1992","journal-title":"J. Behav. Optom."},{"key":"ref_17","first-page":"549","article-title":"Interrater and test-retest reliability of pursuits and saccades","volume":"59","author":"Maples","year":"1988","journal-title":"J. Am. Optom. Assoc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/cxo.13024","article-title":"Diagnosis of oculomotor anomalies in children with learning disorders","volume":"103","author":"Bilbao","year":"2020","journal-title":"Clin. Exp. Optom."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/CHI.0b013e31819996da","article-title":"Oculomotor performance identifies underlying cognitive deficits in attention-deficit\/hyperactivity disorder","volume":"48","author":"Loe","year":"2009","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/OPX.0000000000001498","article-title":"Children with attention-deficit\/hyperactivity disorder show an altered eye movement pattern during reading","volume":"97","author":"Molina","year":"2020","journal-title":"Optom. Vis. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1097\/OPX.0b013e3181a6a4b3","article-title":"Developmental eye movement test: What is it really measuring?","volume":"86","author":"Ayton","year":"2009","journal-title":"Optom. Vis. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1097\/OPX.0000000000001343","article-title":"Differences in oculomotor function between children with sensory processing disorder and typical development","volume":"96","author":"Walker","year":"2019","journal-title":"Optom. Vis. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Tiadi, A., Seassau, M., G\u00e9rard, C., and Bucci, P. (2016). Differences between dyslexic and non-dyslexic children in the performance of phonological visual-auditory recognition tasks: An eye-tracking study. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0159190"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"981","DOI":"10.3389\/fnhum.2014.00981","article-title":"The influence of oculomotor tasks on postural control in dyslexic children","volume":"8","author":"Bucci","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"ref_25","first-page":"63","article-title":"Preparatory neural networks are impaired in adults with attention-deficit\/hyperactivity disorder during the antisaccade task","volume":"2","author":"Alahyane","year":"2012","journal-title":"Neuroimage Clin."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Jainta, S., and Kapoula, Z. (2011). Dyslexic children are confronted with unstable binocular fixation while reading. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0018694"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11881-015-0098-7","article-title":"Evaluation of ocular movements in patients with dyslexia","volume":"65","author":"Vagge","year":"2015","journal-title":"Ann. Dyslexia"},{"key":"ref_28","first-page":"191","article-title":"Spatial and temporal measurements of eye movement in children with dyslexia","volume":"35","year":"2011","journal-title":"Coll. Antropol."},{"key":"ref_29","first-page":"627","article-title":"Vision and sports: A review of the literature","volume":"53","author":"Stine","year":"1982","journal-title":"J. Am. Optom. Assoc."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"562995","DOI":"10.3389\/fpsyg.2020.562995","article-title":"What do football players look at? An eye-tracking analysis of the visual fixations of players in 11v11 elite football match play","volume":"11","author":"Aksum","year":"2020","journal-title":"Front. Psychol."},{"key":"ref_31","first-page":"145","article-title":"What the literature says about sports vision","volume":"3","author":"Hitzeman","year":"1993","journal-title":"Optom. Clin."}],"container-title":["Vision"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2411-5150\/5\/2\/28\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:11:37Z","timestamp":1760163097000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2411-5150\/5\/2\/28"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,7]]},"references-count":31,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,6]]}},"alternative-id":["vision5020028"],"URL":"https:\/\/doi.org\/10.3390\/vision5020028","relation":{},"ISSN":["2411-5150"],"issn-type":[{"value":"2411-5150","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,7]]}}}