{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:16:19Z","timestamp":1787030179110,"version":"build-2736575974"},"reference-count":89,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T00:00:00Z","timestamp":1682208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision"],"abstract":"<jats:p>Biomechanics is a branch of biophysics that deals with mechanics applied to biology. Corneal biomechanics have an important role in managing patients with glaucoma. While evidence suggests that patients with thin and stiffer corneas have a higher risk of developing glaucoma, it also influences the accurate measurement of intraocular pressure. We reviewed the pertinent literature to help increase our understanding of the biomechanics of the cornea and other ocular structures and how they can help optimize clinical and surgical treatments, taking into consideration individual variabilities, improve the diagnosis of suspected patients, and help monitor the response to treatment.<\/jats:p>","DOI":"10.3390\/vision7020036","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T02:31:05Z","timestamp":1682303465000},"page":"36","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Ocular Biomechanics and Glaucoma"],"prefix":"10.3390","volume":"7","author":[{"given":"Rodrigo","family":"Brazuna","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiz S.","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Antonio Pedro University Hospital, Fluminense Federal University, Niter\u00f3i 24033-900, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8330-6432","authenticated-orcid":false,"given":"Marcella Q.","family":"Salom\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04023-062, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno F.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Argumento Institute, Boucherville, QC J4B-2G6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6919-4606","authenticated-orcid":false,"suffix":"Jr.","given":"Renato","family":"Ambr\u00f3sio","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jcrs.2004.09.031","article-title":"Influence of corneal biomechanical properties on intraocular pressure measurement: Quantitative analysis","volume":"31","author":"Liu","year":"2005","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.ophtha.2009.09.023","article-title":"Corneal biomechanical metrics and anterior segment parameters in mild keratoconus","volume":"117","author":"Fontes","year":"2010","journal-title":"Ophthalmology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1590\/S0004-27492013000200011","article-title":"ORA waveform-derived biomechanical parameters to distinguish normal from keratoconic eyes","volume":"76","author":"Luz","year":"2013","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3928\/1081597X-20130819-05","article-title":"Analysis of waveform-derived ORA parameters in early forms of keratoconus and normal corneas","volume":"29","author":"Ventura","year":"2013","journal-title":"J. Refract. Surg."},{"key":"ref_5","first-page":"37","article-title":"Relev\u00e2ncia da biomec\u00e2nica da c\u00f3rnea no glaucoma","volume":"73","year":"2012","journal-title":"Rev. Bras. Oftalmol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1080\/02713683.2022.2059809","article-title":"Corneal Biomechanics Assessment with Ultra High Speed Scheimpflug Camera in Primary Open Angle Glaucoma Compared with Healthy Subjects: A meta-analysis of the Literature","volume":"48","author":"Catania","year":"2023","journal-title":"Curr. Eye Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.ophtha.2020.11.021","article-title":"Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes","volume":"128","author":"Qassim","year":"2021","journal-title":"Ophthalmology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/IJG.0000000000000133","article-title":"Corneal Deformation Parameters Provided by the Corvis-ST Pachy-Tonometer in Healthy Subjects and Glaucoma Patients","volume":"24","author":"Salvetat","year":"2015","journal-title":"J. Glaucoma"},{"key":"ref_9","first-page":"290","article-title":"Relationship between corneal hysteresis and lamina cribrosa displacement after medical reduction of intraocular pressure","volume":"101","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1001\/archopht.1989.01070020298042","article-title":"The relation between glaucomatous damage and optic nerve head mechanical compliance","volume":"107","author":"Zeimer","year":"1989","journal-title":"Arch. Ophthalmol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.exer.2014.08.016","article-title":"Experimental scleral cross-linking increases glaucoma damage in a mouse model","volume":"128","author":"Kimball","year":"2014","journal-title":"Exp. Eye Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jcrs.2004.10.044","article-title":"Determining in vivo biomechanical properties of the cornea with an ocular response analyzer","volume":"31","author":"Luce","year":"2005","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_13","first-page":"562","article-title":"Central corneal thickness, tonometry, and glaucoma risk\u2014A guide for the perplexed","volume":"42","author":"Brandt","year":"2007","journal-title":"Can. J. Ophthalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/j.jcrs.0000000000000626","article-title":"Corneal hysteresis and beyond: Does it involve the sclera?","volume":"47","author":"Roberts","year":"2021","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ajo.2020.03.054","article-title":"Corneal Biomechanical Response Alteration After Scleral Buckling Surgery for Rhegmatogenous Retinal Detachment","volume":"217","author":"Taroni","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.jcrs.2014.04.019","article-title":"Concepts and misconceptions in corneal biomechanics","volume":"40","author":"Roberts","year":"2014","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s00347-007-1532-y","article-title":"The influence of corneal hysteresis and corneal resistance factor on the measurement of intraocular pressure","volume":"104","author":"Hager","year":"2007","journal-title":"Ophthalmologe"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Zhang, H., Sun, Z., Li, L., Sun, R., and Zhang, H. (2020). Comparison of intraocular pressure measured by ocular response analyzer and Goldmann applanation tonometer after corneal refractive surgery: A systematic review and meta-analysis. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-019-1288-6"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3389\/fbioe.2018.00210","article-title":"Biomechanical Impact of the Sclera on Corneal Deformation Response to an Air-Puff: A Finite-Element Study","volume":"6","author":"Nguyen","year":"2018","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/02713683.2022.2125530","article-title":"Clinical Ocular Biomechanics: Where Are We after 20 Years of Progress?","volume":"48","author":"Yuhas","year":"2023","journal-title":"Curr. Eye Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.5005\/jp-journals-10008-1103","article-title":"Ocular Response Analyzer","volume":"6","author":"Kaushik","year":"2021","journal-title":"J. Curr. Glaucoma. Pract."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"107904","DOI":"10.1016\/j.exer.2019.107904","article-title":"Biomechanical contribution of the sclera to dynamic corneal response in air-puff induced deformation in human donor eyes","volume":"191","author":"Nguyen","year":"2020","journal-title":"Exp. Eye Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.jcrs.2014.02.032","article-title":"Deformation response of paired donor corneas to an air puff: Intact whole globe versus mounted corneoscleral rim","volume":"40","author":"Metzler","year":"2014","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1590\/S0034-72802013000200005","article-title":"Dynamic ultra-high speed Scheimpflug imaging for assessing corneal biomechanical properties","volume":"72","author":"Ramos","year":"2013","journal-title":"Rev. Bras. Oftalmol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1080\/02713683.2017.1405044","article-title":"Measurement of Orbital Biomechanical Properties in Patients with Thyroid Orbitopathy Using the Dynamic Scheimpflug Analyzer (Corvis ST)","volume":"43","author":"Leszczynska","year":"2018","journal-title":"Curr. Eye Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3928\/1081597X-20161221-03","article-title":"Introduction of Two Novel Stiffness Parameters and Interpretation of Air Puff-Induced Biomechanical Deformation Parameters With a Dynamic Scheimpflug Analyzer","volume":"33","author":"Roberts","year":"2017","journal-title":"J. Refract. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e0036","DOI":"10.37039\/1982.8551.20220036","article-title":"Corneal Biomechanics and Glaucoma Beyond the Bidirectional Impact of Intraocular Pressure and Corneal Deformation Response","volume":"81","author":"Brazuna","year":"2022","journal-title":"Rev. Bras. Oftalmol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1080\/10255842.2015.1077515","article-title":"Development and validation of a correction equation for Corvis tonometry","volume":"19","author":"Joda","year":"2016","journal-title":"Comput. Methods Biomech. Biomed. Eng."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3928\/1081597X-20160629-01","article-title":"Detection of Keratoconus With a New Biomechanical Index","volume":"32","author":"Vinciguerra","year":"2016","journal-title":"J. Refract. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"434","DOI":"10.3928\/1081597X-20170426-02","article-title":"Integration of Scheimpflug-Based Corneal Tomography and Biomechanical Assessments for Enhancing Ectasia Detection","volume":"33","author":"Ambrosio","year":"2017","journal-title":"J. Refract. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3928\/1081597X-20181012-02","article-title":"Long-term Evaluation of Corneal Biomechanical Properties After Corneal Cross-linking for Keratoconus: A 4-Year Longitudinal Study","volume":"34","author":"Sedaghat","year":"2018","journal-title":"J. Refract. Surg."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3389\/fbioe.2019.00105","article-title":"Determination of Corneal Biomechanical Behavior in-vivo for Healthy Eyes Using CorVis ST Tonometry: Stress-Strain Index","volume":"7","author":"Eliasy","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/IJG.0000000000001486","article-title":"The Relationship Between Corvis ST Tonometry Parameters and Ocular Response Analyzer Corneal Hysteresis","volume":"29","author":"Fujishiro","year":"2020","journal-title":"J. Glaucoma"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"R21","DOI":"10.1093\/hmg\/ddx184","article-title":"Genetics of glaucoma","volume":"26","author":"Wiggs","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3389\/fcell.2020.00452","article-title":"The Neurovascular Unit in Glaucomatous Neurodegeneration","volume":"8","author":"Wareham","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/IJG.0000000000000767","article-title":"Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma","volume":"26","author":"Williams","year":"2017","journal-title":"J. Glaucoma"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s00347-018-0658-4","article-title":"Autoimmunity and glaucoma","volume":"116","author":"Bell","year":"2019","journal-title":"Ophthalmologe"},{"key":"ref_38","first-page":"1603","article-title":"Clinical measurements of aqueous outflow","volume":"34","author":"Grant","year":"1951","journal-title":"Am. J. Ophthalmol."},{"key":"ref_39","first-page":"1670","article-title":"Modulation of outflow resistance by the pores of the inner wall endothelium","volume":"33","author":"Johnson","year":"1992","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1167\/iovs.10-6342","article-title":"Elastic modulus determination of normal and glaucomatous human trabecular meshwork","volume":"52","author":"Last","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1167\/iovs.61.13.29","article-title":"Lysophosphatidic Acid and IL-6 Trans-signaling Interact via YAP\/TAZ and STAT3 Signaling Pathways in Human Trabecular Meshwork Cells","volume":"61","author":"Yemanyi","year":"2020","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Ethier, C.R., and Simmons, C.A. (2007). Introductory Biomechanics: From Cells to Organisms, Cambridge University Press.","DOI":"10.1017\/CBO9780511809217"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1167\/iovs.61.6.30","article-title":"Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype","volume":"61","author":"Dhamodaran","year":"2020","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1113\/JP281011","article-title":"Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow","volume":"599","author":"Yarishkin","year":"2021","journal-title":"J. Physiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"102042","DOI":"10.1016\/j.isci.2021.102042","article-title":"The role of Piezo1 in conventional aqueous humor outflow dynamics","volume":"24","author":"Zhu","year":"2021","journal-title":"iScience"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"C1013","DOI":"10.1152\/ajpcell.00599.2020","article-title":"TRPV4-Rho signaling drives cytoskeletal and focal adhesion remodeling in trabecular meshwork cells","volume":"320","author":"Lakk","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"C652","DOI":"10.1152\/ajpcell.00473.2020","article-title":"The ocular pulse decreases aqueous humor outflow resistance by stimulating nitric oxide production","volume":"320","author":"Madekurozwa","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"14950","DOI":"10.1038\/s41598-021-94391-2","article-title":"Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells","volume":"11","author":"Lee","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1167\/iovs.05-0541","article-title":"Factors influencing optic nerve head biomechanics","volume":"46","author":"Sigal","year":"2005","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"108188","DOI":"10.1016\/j.exer.2020.108188","article-title":"Role of radially aligned scleral collagen fibers in optic nerve head biomechanics","volume":"199","author":"Hua","year":"2020","journal-title":"Exp. Eye Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/ICU.0000000000000829","article-title":"Glaucoma and biomechanics","volume":"33","author":"Safa","year":"2022","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1167\/iovs.62.1.27","article-title":"Regional Differences and Physiologic Behaviors in Peripapillary Scleral Fibroblasts","volume":"62","author":"Szeto","year":"2021","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"20160367","DOI":"10.1098\/rsif.2016.0367","article-title":"The contribution of glycosaminoglycans to the mechanical behaviour of the posterior human sclera","volume":"13","author":"Murienne","year":"2016","journal-title":"J. R. Soc. Interface"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"7215","DOI":"10.1167\/iovs.13-12441","article-title":"Correlation between biomechanical responses of posterior sclera and IOP elevations during micro intraocular volume change","volume":"54","author":"Morris","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"9023","DOI":"10.1167\/iovs.11-8183","article-title":"IOP-induced lamina cribrosa deformation and scleral canal expansion: Independent or related?","volume":"52","author":"Sigal","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1167\/iovs.15-18193","article-title":"Effects of Peripapillary Scleral Stiffening on the Deformation of the Lamina Cribrosa","volume":"57","author":"Coudrillier","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1001\/archopht.1981.03930010139020","article-title":"Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage","volume":"99","author":"Quigley","year":"1981","journal-title":"Arch. Ophthalmol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1167\/iovs.61.13.15","article-title":"So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult","volume":"61","author":"Voorhees","year":"2020","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1007\/s10439-009-9879-7","article-title":"Effects of scleral stiffness properties on optic nerve head biomechanics","volume":"38","author":"Eilaghi","year":"2010","journal-title":"Ann. Biomed. Eng."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ajo.2019.11.017","article-title":"Relationship of Corneal Hysteresis and Anterior Lamina Cribrosa Displacement in Glaucoma","volume":"212","author":"Wong","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.ajo.2005.12.007","article-title":"Central corneal thickness and corneal hysteresis associated with glaucoma damage","volume":"141","author":"Congdon","year":"2006","journal-title":"Am. J. Ophthalmol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1097\/IJG.0b013e3182071b92","article-title":"Lower corneal hysteresis is associated with more rapid glaucomatous visual field progression","volume":"21","author":"Hill","year":"2012","journal-title":"J. Glaucoma"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ajo.2017.12.018","article-title":"A Prospective Longitudinal Study to Investigate Corneal Hysteresis as a Risk Factor for Predicting Development of Glaucoma","volume":"187","author":"Susanna","year":"2018","journal-title":"Am. J. Ophthalmol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1136\/bjo.2010.196899","article-title":"The relationship between corneal hysteresis and the magnitude of intraocular pressure reduction with topical prostaglandin therapy","volume":"96","author":"Agarwal","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1007\/s00417-013-2416-2","article-title":"Corneal biomechanics predict the outcome of selective laser trabeculoplasty in medically uncontrolled glaucoma","volume":"251","author":"Hirneiss","year":"2013","journal-title":"Graefes. Arch. Clin. Exp. Ophthalmol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.ajo.2009.01.008","article-title":"Recovery of corneal hysteresis after reduction of intraocular pressure in chronic primary angle-closure glaucoma","volume":"147","author":"Sun","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.ajo.2004.07.036","article-title":"Central corneal thickness and measured IOP response to topical ocular hypotensive medication in the Ocular Hypertension Treatment Study","volume":"138","author":"Brandt","year":"2004","journal-title":"Am. J. Ophthalmol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1167\/iovs.06-0557","article-title":"Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer","volume":"47","author":"Kotecha","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.ophtha.2008.02.001","article-title":"Changes in central corneal thickness over time: The ocular hypertension treatment study","volume":"115","author":"Brandt","year":"2008","journal-title":"Ophthalmology"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"E803","DOI":"10.1097\/OPX.0b013e3182504214","article-title":"Relative importance of factors affecting corneal hysteresis measurement","volume":"89","author":"Katiyar","year":"2012","journal-title":"Optom. Vis. Sci."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1016\/j.ophtha.2011.01.047","article-title":"Intraocular pressure control and long-term visual field loss in the Collaborative Initial Glaucoma Treatment Study","volume":"118","author":"Musch","year":"2011","journal-title":"Ophthalmology"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/j.ophtha.2004.02.017","article-title":"Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study","volume":"111","author":"Hoffman","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1136\/bjophthalmol-2018-313493","article-title":"Corneal biomechanics and biomechanically corrected intraocular pressure in primary open-angle glaucoma, ocular hypertension and controls","volume":"104","author":"Vinciguerra","year":"2020","journal-title":"Br. J. Ophthalmol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"6514","DOI":"10.1167\/iovs.10-5580","article-title":"Corneal hysteresis and visual field asymmetry in open angle glaucoma","volume":"51","author":"Anand","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_75","first-page":"503","article-title":"Corneal biomechanics in asymmetrical normal-tension glaucoma","volume":"10","author":"Helmy","year":"2016","journal-title":"Clin. Ophthalmol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1167\/iovs.61.4.19","article-title":"Dynamic Scheimpflug Ocular Biomechanical Parameters in Untreated Primary Open Angle Glaucoma Eyes","volume":"61","author":"Miki","year":"2020","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Pradhan, Z.S., Deshmukh, S., Dixit, S., Sreenivasaiah, S., Shroff, S., Devi, S., Webers, C.A.B., and Rao, H.L. (2020). A comparison of the corneal biomechanics in pseudoexfoliation glaucoma, primary open-angle glaucoma and healthy controls using Corvis ST. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0241296"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2147\/OPTH.S350029","article-title":"Corneal Biomechanics for Ocular Hypertension, Primary Open-Angle Glaucoma, and Amyloidotic Glaucoma: A Comparative Study by Corvis ST","volume":"16","author":"Silva","year":"2022","journal-title":"Clin. Ophthalmol."},{"key":"ref_79","first-page":"1475","article-title":"Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues","volume":"43","author":"Zenkel","year":"2002","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1089\/108076803322660422","article-title":"Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells","volume":"19","author":"Sharif","year":"2003","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/02713683.2018.1516781","article-title":"Experimental Evaluation of Travoprost-Induced Changes in Biomechanical Behavior of Ex-Vivo Rabbit Corneas","volume":"44","author":"Zheng","year":"2019","journal-title":"Curr. Eye Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/S0039-6257(02)00306-5","article-title":"Effects of prostaglandins on the aqueous humor outflow pathways","volume":"47","author":"Weinreb","year":"2002","journal-title":"Surv. Ophthalmol."},{"key":"ref_83","first-page":"1514","article-title":"Increased human scleral permeability with prostaglandin exposure","volume":"42","author":"Kim","year":"2001","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1167\/iovs.06-0334","article-title":"Direct matrix metalloproteinase enhancement of transscleral permeability","volume":"48","author":"Lindsey","year":"2007","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1136\/bjophthalmol-2016-308432","article-title":"The impact of chronic use of prostaglandin analogues on the biomechanical properties of the cornea in patients with primary open-angle glaucoma","volume":"101","author":"Meda","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/IJG.0000000000001736","article-title":"Evaluating the Relationship of Intraocular Pressure and Anterior Chamber Volume with Use of Prostaglandin Analogues","volume":"30","author":"Scott","year":"2021","journal-title":"J. Glaucoma"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ogla.2018.08.006","article-title":"The Relationship between the Waveform Parameters from the Ocular Response Analyzer and the Progression of Glaucoma","volume":"1","author":"Aoki","year":"2018","journal-title":"Ophthalmol. Glaucoma"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3928\/1081597X-20130129-03","article-title":"Scheimpflug-based tomography and biomechanical assessment in pressure-induced stromal keratopathy","volume":"29","author":"Ramos","year":"2013","journal-title":"J. Refract. Surg."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/ICO.0b013e318226bf4a","article-title":"Clinical and corneal biomechanical changes after collagen cross-linking with riboflavin and UV irradiation in patients with progressive keratoconus: Results after 2 years of follow-up","volume":"31","author":"Goldich","year":"2012","journal-title":"Cornea"}],"container-title":["Vision"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2411-5150\/7\/2\/36\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:21:52Z","timestamp":1760124112000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2411-5150\/7\/2\/36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,23]]},"references-count":89,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["vision7020036"],"URL":"https:\/\/doi.org\/10.3390\/vision7020036","relation":{},"ISSN":["2411-5150"],"issn-type":[{"value":"2411-5150","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,23]]}}}