{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T13:38:20Z","timestamp":1793281100816,"version":"4.5.0"},"reference-count":44,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T00:00:00Z","timestamp":1694304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision"],"abstract":"<jats:p>People with Down syndrome have more visual problems than the general population. They experience premature ageing, and they are expected to also have an acceleration in worsening visual function. A prospective observational study which includes visual acuity, refractive error, accommodation, binocular and colour vision was performed on young adults with (n = 69) and without (n = 65) Down syndrome and on a senior group (n = 55) without Down syndrome. Results showed significant differences in visual acuity between groups (p &lt; 0.001), and it can be improved with a new prescription in 40% of the participants with Down syndrome. Regarding the accommodative state, no significant differences were found between groups of young people. Concerning binocular vision, 64.7% of strabismus was observed in the group with Down syndrome (p &lt; 0.001). Visual abnormalities are significant in young adults with Down syndrome and are different from those of older people without Down syndrome, some of which can be improved by providing the optimal prescription as well as regular eye examinations.<\/jats:p>","DOI":"10.3390\/vision7030060","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T09:11:18Z","timestamp":1694423478000},"page":"60","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Vision Impairments in Young Adults with Down Syndrome"],"prefix":"10.3390","volume":"7","author":[{"given":"Yolanda","family":"Martin-Perez","sequence":"first","affiliation":[{"name":"Faculty of Optic and Optometry, Department of Optometry and Vision Science, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7377-7967","authenticated-orcid":false,"given":"Guadalupe","family":"Gonzalez-Montero","sequence":"additional","affiliation":[{"name":"Faculty of Optic and Optometry, Department of Optometry and Vision Science, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7120-9464","authenticated-orcid":false,"given":"Angel L.","family":"Gutierrez-Hernandez","sequence":"additional","affiliation":[{"name":"Faculty of Optic and Optometry, Department of Optometry and Vision Science, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanesa","family":"Bl\u00e1zquez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Faculty of Optic and Optometry, Department of Optometry and Vision Science, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3841-6514","authenticated-orcid":false,"given":"Celia","family":"S\u00e1nchez-Ramos","sequence":"additional","affiliation":[{"name":"Faculty of Optic and Optometry, Department of Optometry and Vision Science, Complutense University of Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/nrn3314","article-title":"Down syndrome: The brain in trisomic mode","volume":"13","author":"Dierssen","year":"2012","journal-title":"Nat. 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