{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:33:04Z","timestamp":1785850384801,"version":"3.56.0"},"reference-count":22,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vision"],"abstract":"<jats:p>Purpose: The purpose of this paper is to investigate the relationship between short-wavelength autofluorescence (SWAF) and infrared autofluorescence (IRAF) patterns in pachychoroid neovasculopathy (PNV) with serous retinal detachment (SRD). Methods: This study used an observational case series of 62 eyes of 58 consecutive patients diagnosed with symptomatic PNV from January 2019 and October 2021 at a single institution. SWAF and IRAF patterns were analyzed with disease chronicity, and autofluorescence changes in macular neovascularization (MNV) were assessed in two images. Results: SWAF patterns and the mean duration of symptoms were as follows: blocked (15 eyes, 24%), 1.0 months; mottled (8 eyes, 13%), 2.8 months; hyper (24 eyes, 39%), 5.0 months; hyper\/hypo (10 eyes, 16%), 7.0 months; descending tract (5 eyes, 8%), 12.0 months (p &lt; 0.01). IRAF patterns and the mean duration of symptoms were as follows: blocked (17 eyes, 27%), 1.0 months; hyper (22 eyes, 35%), 4.0 months; mixed\/hyper dominant (9 eyes, 15%), 5.0 months; mixed\/hypo dominant (9 eyes, 15%), 6.8 months; descending tract (5 eyes, 8%), 12.0 months (p &lt; 0.01). Abnormal autofluorescence corresponding to MNV lesion was seen in 34 eyes (55%) with SWAF and 59 eyes (95%) with IRAF (p &lt; 0.01). Conclusions: SWAF and IRAF show multiple patterns and are related to disease chronicity in symptomatic PNV. IRAF could be helpful in detecting the lesion of MNV.<\/jats:p>","DOI":"10.3390\/vision9020038","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T20:42:00Z","timestamp":1745268120000},"page":"38","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Short-Wavelength and Infrared Autofluorescence Imaging in Pachychoroid Neovasculopathy"],"prefix":"10.3390","volume":"9","author":[{"given":"Norihiko","family":"Nakagawa","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Sakai City Medical Center, Osaka 593-8304, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9979-7045","authenticated-orcid":false,"given":"Takuya","family":"Shunto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Osaka University Graduate School of Medicine, The University of Osaka, Osaka 565-0871, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7796-6354","authenticated-orcid":false,"given":"Issei","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sakai City Medical Center, Osaka 593-8304, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sakai City Medical Center, Osaka 593-8304, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4856-9453","authenticated-orcid":false,"given":"Miki","family":"Sawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sakai City Medical Center, Osaka 593-8304, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/IAE.0000000000000331","article-title":"Pachychoroid Neovasculopathy","volume":"35","author":"Pang","year":"2015","journal-title":"Retina"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41433-018-0158-4","article-title":"Pachychoroid Disease","volume":"33","author":"Cheung","year":"2019","journal-title":"Eye"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s10384-020-00740-5","article-title":"Pachychoroid Disease: A New Perspective on Exudative Maculopathy","volume":"64","author":"Yanagi","year":"2020","journal-title":"Jpn. 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