{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:45:26Z","timestamp":1776401126407,"version":"3.51.2"},"reference-count":213,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T00:00:00Z","timestamp":1610064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>One of the main constraints in aquaculture production is farmed fish vulnerability to diseases due to husbandry practices or external factors like pollution, climate changes, or even the alterations in the dynamic of product transactions in this industry. It is though important to better understand and characterize the intervenients in the process of a disease outbreak as these lead to huge economical losses in aquaculture industries. High-throughput technologies like proteomics can be an important characterization tool especially in pathogen identification and the virulence mechanisms related to host-pathogen interactions on disease research and diagnostics that will help to control, prevent, and treat diseases in farmed fish. Proteomics important role is also maximized by its holistic approach to understanding pathogenesis processes and fish responses to external factors like stress or temperature making it one of the most promising tools for fish pathology research.<\/jats:p>","DOI":"10.3390\/ani11010125","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T08:58:34Z","timestamp":1610096314000},"page":"125","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Fish Pathology Research and Diagnosis in Aquaculture of Farmed Fish; a Proteomics Perspective"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4932-4968","authenticated-orcid":false,"given":"M\u00e1rcio","family":"Moreira","sequence":"first","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"IPMA\u2014Portuguese Institute for the Sea and Atmosphere, EPPO\u2014Aquaculture Research Station, Av. Parque Natural da Ria Formosa s\/n, 8700-194 Olh\u00e3o, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0274-5957","authenticated-orcid":false,"given":"Denise","family":"Schrama","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]},{"given":"Ana Paula","family":"Farinha","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7237-5053","authenticated-orcid":false,"given":"Marco","family":"Cerqueira","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-2870","authenticated-orcid":false,"given":"Cl\u00e1udia","family":"Raposo de Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]},{"given":"Raquel","family":"Carrilho","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9668-1204","authenticated-orcid":false,"given":"Pedro","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"CCMAR\u2014Centre of Marine Sciences, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"},{"name":"University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,8]]},"reference":[{"key":"ref_1","unstructured":"Bank, T.W. 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