{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T03:01:18Z","timestamp":1760151678407,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Portuguese Foundation for Science and Technology","award":["UIDB\/CVT\/00772\/2020","UIDB\/AGR\/04033\/2020"],"award-info":[{"award-number":["UIDB\/CVT\/00772\/2020","UIDB\/AGR\/04033\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>A 3-to-4-year-old roe deer (Capreolus capreolus L.) was admitted to the Veterinary Hospital. Although it showed well-developed antlers with retained velvet, an external female appearance and genitalia were evident. External biometrical measurements were taken for the antlers, and a computed tomography was performed. Molecular studies targeting the SRY gene were performed, and a PIS (polled intersex syndrome) mutation diagnosis was implemented. The gonads consisted of a right testicle paired with a left ovotestis. Histologically, the ovary-like structures in the ovotestis were functional, but the testis, as the testis-like structure in the ovotestis, did not show active spermatogenesis. No evidence of SRY gene was detected by PCR, suggesting an XX-chromosome constitution. Additionally, polled intersex syndrome (PIS) deletion was not detected in the case under study. The clinical and histopathological findings confirmed the DSD with the presence of a testicle and a contralateral ovotestis.<\/jats:p>","DOI":"10.3390\/ani12070865","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T21:40:14Z","timestamp":1648590014000},"page":"865","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Case of XX Disorder of Sexual Development in a Female-Phenotype Roe Deer (Capreolus capreolus L.) Associated with Antlers Growth with Retained Velvet"],"prefix":"10.3390","volume":"12","author":[{"given":"Filipe","family":"Silva","sequence":"first","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6330-4560","authenticated-orcid":false,"given":"Isabel","family":"Pires","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3902-5374","authenticated-orcid":false,"given":"Justina","family":"Prada","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"Miguel","family":"Queir\u00f3s","sequence":"additional","affiliation":[{"name":"Department of Genetics and Biotechnology, School of Life and Environmental Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1538-0467","authenticated-orcid":false,"given":"Aurora","family":"Monz\u00f3n","sequence":"additional","affiliation":[{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Forest and Landscape, School of Agrarian and Veterinary Sciences, CIFAP, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4587-0221","authenticated-orcid":false,"given":"Jos\u00e9","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3191-7853","authenticated-orcid":false,"given":"Roberto","family":"Sargo","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"Filipa","family":"Loureiro","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"Lu\u00eds","family":"Sousa","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"Joana","family":"Valente","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8796-5037","authenticated-orcid":false,"given":"Carlos","family":"Viegas","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"M\u00e1rio","family":"Ginja","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"given":"Estela","family":"Bastos","sequence":"additional","affiliation":[{"name":"Department of Genetics and Biotechnology, School of Life and Environmental Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9566-3100","authenticated-orcid":false,"given":"Ana","family":"Martins-Bessa","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5049-4473","authenticated-orcid":false,"given":"Isabel","family":"Dias","sequence":"additional","affiliation":[{"name":"Exotic and Wild Animal Service, Veterinary Hospital of University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Veterinary and Animal Science Research Centre (CECAV), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"},{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes e Alto Douro (UTAD), P.O. Box 1013, 5000-801 Vila Real, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"ref_1","first-page":"208","article-title":"The frequency of antlered female and antlerless male roe deer (Capreolus capreolus) in a population in south-east Norway","volume":"45","author":"Mysterud","year":"1999","journal-title":"Z. 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