{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:41:17Z","timestamp":1764873677016,"version":"build-2065373602"},"reference-count":63,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animals"],"abstract":"<jats:p>Our objective was to analyze the main anatomical structures of the dolphin head during its developmental stages. Most dolphin studies use only one fetal specimen due to the difficulty in obtaining these materials. Magnetic resonance imaging (MRI) and computed tomography (CT) of two fetuses (younger and older) and a perinatal specimen cadaver of striped dolphins were scanned. Only the older fetus was frozen and then was transversely cross-sectioned. In addition, gross dissections of the head were made on a perinatal and an adult specimen. In the oral cavity, only the mandible and maxilla teeth have started to erupt, while the most rostral teeth have not yet erupted. No salivary glands and masseter muscle were observed. The melon was well identified in CT\/MRI images at early stages of development. CT and MRI images allowed observation of the maxillary sinus. The orbit and eyeball were analyzed and the absence of infraorbital rim together with the temporal process of the zygomatic bone holding periorbit were described. An enlarged auditory tube was identified using anatomical sections, CT, and MRI. We also compare the dolphin head anatomy with some mammals, trying to underline the anatomical and physiological changes and explain them from an ontogenic point of view.<\/jats:p>","DOI":"10.3390\/ani9121139","type":"journal-article","created":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T11:27:22Z","timestamp":1576236442000},"page":"1139","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Study of the Head during Prenatal and Perinatal Development of Two Fetuses and One Newborn Striped Dolphin (Stenella coeruleoalba, Meyen 1833) Using Dissections, Sectional Anatomy, CT, and MRI: Anatomical and Functional Implications in Cetaceans and Terrestrial Mammals"],"prefix":"10.3390","volume":"9","author":[{"given":"\u00c1lvaro","family":"Garc\u00eda de los R\u00edos y Loshuertos","sequence":"first","affiliation":[{"name":"Departamento de Anatom\u00eda y Anatom\u00eda Patol\u00f3gica Comparadas, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6797-8220","authenticated-orcid":false,"given":"Alberto","family":"Arencibia Espinosa","sequence":"additional","affiliation":[{"name":"Departamento de Morfolog\u00eda. Anatom\u00eda y Embriolog\u00eda, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Trasmonta\u00f1a, Arucas, 35416 Las Palmas de Gran Canaria, Spain"}]},{"given":"Marta","family":"Soler Lagu\u00eda","sequence":"additional","affiliation":[{"name":"Departamento de Medicina y Cirug\u00eda, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1770-9521","authenticated-orcid":false,"given":"Francisco","family":"Gil Cano","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Anatom\u00eda Patol\u00f3gica Comparadas, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain"}]},{"given":"Francisco","family":"Mart\u00ednez Gomariz","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Anatom\u00eda Patol\u00f3gica Comparadas, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain"}]},{"given":"Alfredo","family":"L\u00f3pez Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda\u2014CESAM, Universidade de Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0782-8970","authenticated-orcid":false,"given":"Gregorio","family":"Ram\u00edrez Zarzosa","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Anatom\u00eda Patol\u00f3gica Comparadas, Facultad de Veterinaria, Universidad de Murcia, 30100 Murcia, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5479\/si.00810282.627","article-title":"The therian skull. A lexicon with emphasis on the odontocetes","volume":"627","author":"Mead","year":"2009","journal-title":"Smithson. Contr. Zool."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Berta, A., Sumich, J.L., and Kovacs, K.M. (2005). Cetacean evolution and systematics. Marine Mammal Evolutionary Biology, Academic Press. [2nd ed.].","DOI":"10.1016\/B978-012088552-7\/50005-9"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Roston, R.A., and Roth, V.L. (2019). Cetacean Skull Telescoping Brings Evolution of Cranial Sutures into Focus. Anat. Rec.","DOI":"10.1002\/ar.24079"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1748-7692.2010.00445.x","article-title":"Allometric patterns of fetal head growth in mysticetes and odontocetes: Comparison of Balaena mysticetus and Stenella attenuata","volume":"27","author":"Armfield","year":"2011","journal-title":"Marine Mammal Sci."},{"key":"ref_5","first-page":"1","article-title":"Embryology of dolphins. Staging and ageing of embryos and fetuses of some cetaceans","volume":"157","author":"Sterba","year":"2000","journal-title":"Adv. Anat. Embryol. Cell. Biol."},{"key":"ref_6","unstructured":"Miller, D.L. (2007). Embryogenesis and development in Stenella atenuatta and other cetaceans. Reproductive Biology and Phylogeny in Cetacea, Whales, Dolphins and Porpoises, Science Publishers."},{"key":"ref_7","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Prenatal development in cetaceans. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_8","first-page":"105","article-title":"Sections of the dolphin\u2019s head (Stenella coeruleoalba)","volume":"19","author":"Hosokawa","year":"1965","journal-title":"Sci. Rep. Whales Res. Inst."},{"key":"ref_9","first-page":"1","article-title":"Cross-sectional anatomy, computed tomography and magnetic resonance imaging of the head of common dolphin (Delphinus delphis) and striped dolphin (Stenella coeruleoalba)","volume":"43","author":"Degollada","year":"2014","journal-title":"J. Vet. Med. Anat. Histol. Embryol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1136\/vr.155.7.208","article-title":"Hydrocephalus in a newborn bottlenosed dolphin (Tursiops truncatus)","volume":"155","author":"Corpa","year":"2004","journal-title":"Vet. Rec."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1740-8261.2006.00167.x","article-title":"Anatomic and Computed tomography atlas of the head of the newborn bottlenosed dolphin (Tursiops truncatus)","volume":"47","author":"Liste","year":"2006","journal-title":"Vet. Radiol. Ultrasound."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1002\/jmor.10477","article-title":"Head morphology in perinatal dolphins: A window into phylogeny and ontogeny","volume":"267","author":"Rauschmann","year":"2006","journal-title":"J. Morphol."},{"key":"ref_13","first-page":"1","article-title":"The skull of the foetal narwhal Monodon monoceros L.","volume":"235","author":"Eales","year":"1950","journal-title":"Phil. Trans. R. Soc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s004290100167","article-title":"Magnetic resonance imaging and three-dimensional reconstructions of the brain of a fetal common dolphin, Delphinus delphis","volume":"203","author":"Marino","year":"2001","journal-title":"Anat. Embryol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1002\/ar.20612","article-title":"Neuroanatomy of the subadult and fetal brain of the atlantic white-sided dolphin (Lagenorhynchus acutus) from in situ magnetic resonance images","volume":"290","author":"Montie","year":"2007","journal-title":"Anat. Rec."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/jmor.20478","article-title":"The extracranial arterial system in the heads of beaked whales, with implications on diving physiology and pathogenesis","volume":"277","author":"Costidis","year":"2016","journal-title":"J. Morphol."},{"key":"ref_17","first-page":"209","article-title":"Observations on the skull in foetal specimens of whales of the genera Megaptera and Balaenoptera","volume":"211","author":"Ridewood","year":"1922","journal-title":"Phil. Trans. R. Soc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1748-7692.2009.00305.x","article-title":"Observations on the musculoskeletal anatomy of the head of a neonate gray whale (Eschrichtius robustus)","volume":"26","author":"Johnston","year":"2010","journal-title":"Mar. Mammal. Sci."},{"key":"ref_19","first-page":"389","article-title":"The sei whale (Balaenoptera borealis, Lesson). Anatomy of a foetus of Balaenoptera borealis. Monographs of the Pacific Cetacea","volume":"1","author":"Schulte","year":"1916","journal-title":"Mem. Am. Mus. Nat. Hist. New Ser."},{"key":"ref_20","unstructured":"O\u2019Rahilly, R., and M\u00fcller, F. (1987). Developmental Stages in Human Embryos, Carnegie Institute."},{"key":"ref_21","first-page":"725","article-title":"Growth and reproduction of the eastern spinner dolphin, a geographical form of Stenella longirostris in the eastern tropical pacific","volume":"75","author":"Perrin","year":"1977","journal-title":"Fish Bull."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1136\/vr.154.8.228","article-title":"Prediction from ultrasonographic measurements of the expected delivery date in two species of bottlenose","volume":"154","author":"Lacave","year":"2004","journal-title":"Vet. Rec."},{"key":"ref_23","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Age estimation. Encyclopedia of Marine Mammals, Academic Pres. [2nd ed.]."},{"key":"ref_24","unstructured":"Schaller, O. (1992). Illustrated Veterinary Anatomical Nomenclature, Ferdinand Enke Verlag."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/ar.22678","article-title":"Anatomy and age estimation of an early blue whale (Balaenoptera musculus) fetus","volume":"296","author":"Roston","year":"2013","journal-title":"Anat. Rec."},{"key":"ref_26","unstructured":"Brill, E.J. (1988). Whales of the World, Bess Pr Inc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.7717\/peerj.24","article-title":"Development and evolution of the unique cetacean dentition","volume":"1","author":"Armfield","year":"2013","journal-title":"PeerJ"},{"key":"ref_28","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Skull anatomy. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_29","unstructured":"Huggenberger, S., Oelschl\u00e4ger, H., and Cozzi, B. (2019). Atlas of the Anatomy of Dolphins and Whales, Academic Press, Elsevier."},{"key":"ref_30","unstructured":"Cozzi, B., Huggenberger, S., and Oelschl\u00e4ger, H. (2017). Anatomy of Dolphins. Insights into Body Structure and Function, Academic Press."},{"key":"ref_31","unstructured":"Sandoval, J. (2000). Tratado de Anatom\u00eda Veterinaria. Tomo III: Cabeza y Sistemas Viscerales, Imprenta Sorles."},{"key":"ref_32","unstructured":"Nickel, R., Schummer, A., and Seiferle, E. (1986). The Anatomy of the Domestic Animals. The Locomotor System of the Domestic Mammals, Verlag Paul Parey."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/ar.20538","article-title":"Adaptations of the cetacean hyolingual apparatus for aquatic feeding and thermoregulation","volume":"290","author":"Werth","year":"2007","journal-title":"Anat. Rec."},{"key":"ref_34","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Feeding strategies and tactics. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature11135","article-title":"Discovery of a sensory organ that coordinates lunge feeding in rorqual whales","volume":"485","author":"Pyenson","year":"2012","journal-title":"Nature"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1644\/BRB-125","article-title":"Maxillomandibular cam articulation discovered in North Atlantic minke whale","volume":"85","author":"Lambertsen","year":"2004","journal-title":"J. Mammal."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1177\/104063879100300317","article-title":"Adenocarcinoma of the salivary gland in a beluga whale (Delphinapterus leucas)","volume":"3","author":"Girard","year":"1991","journal-title":"J. Vet. Diagn. Invest."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/jmor.10628","article-title":"Morphology on the melon and its tendinous connections to the facial muscles in bottlenose dolphins (Tursiops truncatus)","volume":"269","author":"Harper","year":"2008","journal-title":"J. Morphol."},{"key":"ref_39","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Beluga whale. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_40","first-page":"71","article-title":"Funktion und Evolution der Delphinnase","volume":"113","author":"Behrmann","year":"1983","journal-title":"Nat. Mus."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1002\/ar.20792","article-title":"Sisters of the sinuse cetacean air sacs","volume":"291","author":"Reidenberg","year":"2008","journal-title":"Anat. Rec."},{"key":"ref_42","first-page":"103","article-title":"The Functional Anatomy of the Delphinid Nose","volume":"114","author":"Lawrence","year":"1956","journal-title":"Bull. Mus. Comp. Zool."},{"key":"ref_43","first-page":"37","article-title":"The occurrence and position of the \u201cconnecting sac\u201d in the nasal tract complex of small odontocetes (Mammalia, Cetacea). University of Amsterdam","volume":"246","author":"Schenkkan","year":"1971","journal-title":"Beaufortia"},{"key":"ref_44","first-page":"1","article-title":"Comparative facial anatomy of beaked whales (Ziphiidae) and a systematic revision among the families of extant odontoceti","volume":"405","author":"Heyning","year":"1989","journal-title":"Nat. Hist. Mus. Los Angel. Cty."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1121\/1.420593","article-title":"Visualizing dolphin sonar signal generation using high speed video endoscopy","volume":"102","author":"Cranford","year":"1997","journal-title":"J. Acoust. Soc. Am."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1097-4687(199606)228:3<223::AID-JMOR1>3.0.CO;2-3","article-title":"Functional morphology and homology in the Odontocete nasal complex: Implications for sound generation","volume":"228","author":"Cranford","year":"1996","journal-title":"J. Morph."},{"key":"ref_47","unstructured":"Brudzynski, S.M. (2010). Generation of sound in marine mammals. Handbook of Mammalian Vocalization\u2014An Integrative Neuroscience Approach, Academic Press\/Elsevier."},{"key":"ref_48","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Echolocation. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_49","unstructured":"Perrin, W.F., W\u00fcrsig, B., and Thewissen, J.G.M. (2009). Cetacean prenatal development. Encyclopedia of Marine Mammals, Academic Press. [2nd ed.]."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/jmor.20075","article-title":"Comparative morphology of porpoise (Cetacea: Phocaenidae) pterygoid sinuses: Phylogenetic and functional implications","volume":"274","author":"Racicot","year":"2013","journal-title":"J. Morphol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.ympev.2012.10.012","article-title":"A phylogenetic blueprint for a modern whale","volume":"66","author":"Gatesy","year":"2013","journal-title":"Mol. Phylogenet. Evol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/ar.20539","article-title":"Breaking symmetry: The marine environment, prey size, and the evolution of asymmetry in cetacean skulls","volume":"290","author":"Macleod","year":"2007","journal-title":"Anat. Rec."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1086\/394293","article-title":"The history of the whales: Their adaptation to life in the water","volume":"3","author":"Kellogg","year":"1928","journal-title":"Q. Rev. Biol."},{"key":"ref_54","first-page":"1","article-title":"Hearing in cetaceans-evolution of the accessory air sacs and the structure and function of the outer and middle ears in recent cetaceans","volume":"7","author":"Fraser","year":"1960","journal-title":"Bull. Br. Mus."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1002\/ar.21388","article-title":"Development of the skull of the pantropical spotted dolphin (Stenella attenuata)","volume":"294","author":"Moran","year":"2011","journal-title":"Anat. Rec."},{"key":"ref_56","unstructured":"McGeady, T.A., Quinn, P.J., Fitzpatrick, E.S., Ryan, M.T., Kilroy, D., and Lonergan, P. (2017). Veterinary Embryology, Wiley Blackwell."},{"key":"ref_57","unstructured":"Garc\u00eda Monterde, J., and Gil Cano, F. (2013). Embriolog\u00eda Veterinaria: Un Enfoque Din\u00e1mico del Desarrollo Animal, Inter-m\u00e9dica."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1242\/jeb.01207","article-title":"Structural and functional imaging of bottlenose dolphin (Tursiops truncatus) cranial anatomy","volume":"207","author":"Houser","year":"2004","journal-title":"J. Exp. Biol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1644\/1545-1542(2005)086<0139:PIOSSA>2.0.CO;2","article-title":"Phylogenetic implications of skull structure and feeding behaviour in Balaenopterids (Cetacea, Mysticeti)","volume":"86","author":"Bouetel","year":"2005","journal-title":"J. Mammal."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/ar.21165","article-title":"Quantitative computed tomography of humpback whale (Megaptera novaeangliae) mandibles: Mechanical implications for rorqual lunge-feeding","volume":"293","author":"Field","year":"2010","journal-title":"Anat. Rec."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/ar.1092400417","article-title":"Anatomy of the hyoid apparatus in Odontoceti (toothed whales): Specializations of their skeleton and musculature compared with those of terrestrial mammals","volume":"240","author":"Reidenberg","year":"1994","journal-title":"Anat. Rec."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/ar.23107","article-title":"Tongue and Hyoid Musculature and Functional Morphology of a Neonate Gray Whale (Cetacea, Mysticeti, Eschrichtius robustus)","volume":"298","author":"Kienle","year":"2015","journal-title":"Anat. Rec."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/jmor.20367","article-title":"Prenatal cranial ossification of the humpback whale (Megaptera novaeangliae)","volume":"276","author":"Hampe","year":"2015","journal-title":"J. Morph."}],"container-title":["Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2615\/9\/12\/1139\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:42:07Z","timestamp":1760190127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2615\/9\/12\/1139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,13]]},"references-count":63,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["ani9121139"],"URL":"https:\/\/doi.org\/10.3390\/ani9121139","relation":{},"ISSN":["2076-2615"],"issn-type":[{"type":"electronic","value":"2076-2615"}],"subject":[],"published":{"date-parts":[[2019,12,13]]}}}