{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T07:30:06Z","timestamp":1768548606120,"version":"3.49.0"},"reference-count":93,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T00:00:00Z","timestamp":1629676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/115643\/2016"],"award-info":[{"award-number":["SFRH\/BD\/115643\/2016"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2020.07826.BD"],"award-info":[{"award-number":["2020.07826.BD"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["POCI-01-0145- 646 FEDER-029343"],"award-info":[{"award-number":["POCI-01-0145- 646 FEDER-029343"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/05748\/2020"],"award-info":[{"award-number":["UIDB\/05748\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDP\/05748\/2020"],"award-info":[{"award-number":["UIDP\/05748\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/50006\/2020"],"award-info":[{"award-number":["UIDB\/50006\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDP\/50006\/2020"],"award-info":[{"award-number":["UIDP\/50006\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Given the widespread use of glyphosate (GLY), this agrochemical is becoming a source of contamination in agricultural soils, affecting non-target plants. Therefore, sustainable strategies to increase crop tolerance to GLY are needed. From this perspective and recalling silicon (Si)\u2019s role in alleviating different abiotic stresses, the main goal of this study was to assess if the foliar application of Si, either as bulk or nano forms, is capable of enhancing Solanum lycopersicum L. tolerance to GLY (10 mg kg\u22121). After 28 day(s), GLY-treated plants exhibited growth-related disorders in both shoots and roots, accompanied by an overproduction of superoxide anion (O2\u2022\u2212) and malondialdehyde (MDA) in shoots. Although plants solely exposed to GLY have activated non-enzymatic antioxidant mechanisms (proline, ascorbate and glutathione), a generalized inhibition of the antioxidant enzymes was found, suggesting the occurrence of great redox disturbances. In response to Si or nano-SiO2 co-application, most of GLY phytotoxic effects on growth were prevented, accompanied with a better ROS removal, especially by an upregulation of the main antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT) and ascorbate peroxidase (APX). Overall, results pointed towards the potential of both sources of Si to reduce GLY-induced oxidative stress, without major differences between their efficacy.<\/jats:p>","DOI":"10.3390\/antiox10081320","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T10:24:17Z","timestamp":1629714257000},"page":"1320","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Silicon Improves the Redox Homeostasis to Alleviate Glyphosate Toxicity in Tomato Plants\u2014Are Nanomaterials Relevant?"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3330-2024","authenticated-orcid":false,"given":"Cristiano","family":"Soares","sequence":"first","affiliation":[{"name":"GreenUPorto\u2014Sustainable Agrifood Production Research Centre and INOV4AGRO, Biology Department, Rua do Campo Alegre s\/n, Faculty of Sciences of University of Porto (FCUP), 4169-007 Porto, Portugal"}]},{"given":"Pedro","family":"Nadais","sequence":"additional","affiliation":[{"name":"GreenUPorto\u2014Sustainable Agrifood Production Research Centre and INOV4AGRO, Biology Department, Rua do Campo Alegre s\/n, Faculty of Sciences of University of Porto (FCUP), 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4450-3596","authenticated-orcid":false,"given":"Bruno","family":"Sousa","sequence":"additional","affiliation":[{"name":"GreenUPorto\u2014Sustainable Agrifood Production Research Centre and INOV4AGRO, Biology Department, Rua do Campo Alegre s\/n, Faculty of Sciences of University of Porto (FCUP), 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8021-4783","authenticated-orcid":false,"given":"Edgar","family":"Pinto","sequence":"additional","affiliation":[{"name":"LAQV\/REQUIMTE, Laboratory of Bromatology and Hydrology, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto (FFUP), Rua de Jorge Viterbo Ferreira no. 228, 4050-313 Porto, Portugal"},{"name":"School of Health, Department of Environmental Health, P.Porto (ESS-P.Porto), Rua Dr. Ant\u00f3nio Bernardino de Almeida, 400, 4200-072 Porto, Portugal"}]},{"given":"Isabel M. P. L. V. O.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"LAQV\/REQUIMTE, Laboratory of Bromatology and Hydrology, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto (FFUP), Rua de Jorge Viterbo Ferreira no. 228, 4050-313 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6857-5968","authenticated-orcid":false,"given":"Ruth","family":"Pereira","sequence":"additional","affiliation":[{"name":"GreenUPorto\u2014Sustainable Agrifood Production Research Centre and INOV4AGRO, Biology Department, Rua do Campo Alegre s\/n, Faculty of Sciences of University of Porto (FCUP), 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7756-5243","authenticated-orcid":false,"given":"Fernanda","family":"Fidalgo","sequence":"additional","affiliation":[{"name":"GreenUPorto\u2014Sustainable Agrifood Production Research Centre and INOV4AGRO, Biology Department, Rua do Campo Alegre s\/n, Faculty of Sciences of University of Porto (FCUP), 4169-007 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,23]]},"reference":[{"key":"ref_1","unstructured":"FAO (2017). 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