{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T23:21:36Z","timestamp":1773184896709,"version":"3.50.1"},"reference-count":62,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Operational Programme Integrated Infrastructure for the project: Long-term strategic research of prevention, intervention, and mechanisms of obesity and its comorbidities","award":["IMTS: 313011V344"],"award-info":[{"award-number":["IMTS: 313011V344"]}]},{"name":"European Regional Development Fund","award":["IMTS: 313011V344"],"award-info":[{"award-number":["IMTS: 313011V344"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Polyphenol-rich foods protect the cellular systems of the human body from oxidative damage, thereby reducing the risk of chronic diseases such as cardiovascular disease (CVD). We investigated the effect of phenolic-rich apple\/berry juice (chokeberry, blueberry, and cranberry) on lipidemic profiles in overweight\/obese women. The 6 week single-arm pre\u2013post intervention study involved 20 women (mean age 52.95 \u00b1 5.8 years, body mass index \u226525 kg\/m2, and \u22651 CVD risk factors) consuming 300 mL\/day of the apple\/berry juice. Lipid profile, low-density lipoprotein (LDL) subfractions assessed using Lipoprint\u00ae electrophoresis, and other parameters related to cardiovascular risk (C-reactive protein, glucose, blood pressure) were analyzed before and again after the intervention in the monitored group of women. High-density lipoprotein cholesterol (HDL-C) increased from 1.30 \u00b1 0.29 to 1.55 \u00b1 0.32, magnesium from 0.85 \u00b1 0.03 to 0.90 \u00b1 0.05, and total antioxidant status from 1.68 \u00b1 0.08 to 1.81 \u00b1 0.10. The LDL\/HDL ratio significantly decreased from 3.40 \u00b1 0.99 to 2.66 \u00b1 0.63 mmol\/L, and the glucose from 5.50 \u00b1 0.72 to 5.24 \u00b1 0.74 mmol\/L. However, the hs-CRP did not change significantly. Women with atherogenic subfractions LDL3-7 at baseline (n = 6) showed a significant reduction from 0.45 \u00b1 0.19 to 0.09 \u00b1 0.07 mmol\/L. Overweight\/obese women may benefit from apple\/berry juice as part of a healthy lifestyle to improve their lipid profile, and thus, contribute to cardiovascular health.<\/jats:p>","DOI":"10.3390\/antiox11112239","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T02:34:58Z","timestamp":1668393298000},"page":"2239","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Modulation of Lipid Profile and Lipoprotein Subfractions in Overweight\/Obese Women at Risk of Cardiovascular Diseases through the Consumption of Apple\/Berry Juice"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1721-7161","authenticated-orcid":false,"given":"Marta","family":"Habanova","sequence":"first","affiliation":[{"name":"The Institute of Nutrition and Genomics, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 94976 Nitra, Slovakia"}]},{"given":"Maria","family":"Holovicova","sequence":"additional","affiliation":[{"name":"The AgroBioTech Research Center, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 94976 Nitra, Slovakia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6270-7595","authenticated-orcid":false,"given":"Hana","family":"Scepankova","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Chemistry Department, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"Centro de Investiga\u00e7\u00e3o de Montanha, Instituto Polit\u00e9cnico de Bragan\u00e7a, 5300-252 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5211-5411","authenticated-orcid":false,"given":"Marta","family":"Lorkova","sequence":"additional","affiliation":[{"name":"The AgroBioTech Research Center, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 94976 Nitra, Slovakia"}]},{"given":"Jan","family":"Gazo","sequence":"additional","affiliation":[{"name":"The Institute of Plant and Environmental Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 94976 Nitra, Slovakia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8275-7311","authenticated-orcid":false,"given":"Martina","family":"Gazarova","sequence":"additional","affiliation":[{"name":"The Institute of Nutrition and Genomics, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 94976 Nitra, Slovakia"}]},{"given":"Carlos A.","family":"Pinto","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Chemistry Department, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5536-6056","authenticated-orcid":false,"given":"Jorge A.","family":"Saraiva","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Chemistry Department, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"Leticia M.","family":"Estevinho","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o de Montanha, Instituto Polit\u00e9cnico de Bragan\u00e7a, 5300-252 Bragan\u00e7a, Portugal"},{"name":"Laborat\u00f3rio para a Sustentabilidade e Tecnologia em Regi\u00f5es de Montanha, Campus de Santa Apol\u00f3nia, Instituto Polit\u00e9cnico de Bragan\u00e7a, 5300-253 Bragan\u00e7a, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/oby.21344","article-title":"Cardiometabolic disease Risk in Metabolically Healthy and Unhealthy Obesity: Stability of Metabolic Health Status in Adults","volume":"24","author":"Guo","year":"2016","journal-title":"Obesity"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.metabol.2018.09.005","article-title":"The epidemiology of obesity","volume":"92","author":"Chung","year":"2019","journal-title":"Metabolism"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Battineni, G., Sagaro, G.G., Chintalapudi, N., Amenta, F., Tomassoni, D., and Tayebati, S.K. 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