{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:17:39Z","timestamp":1777411059542,"version":"3.51.4"},"reference-count":45,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T00:00:00Z","timestamp":1576800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["H2020 Marie Sk\u0142odowska-Curie Actions, grant number 642014"],"award-info":[{"award-number":["H2020 Marie Sk\u0142odowska-Curie Actions, grant number 642014"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Natural polyphenols are important dietary antioxidants that significantly benefit human health. Coffee and tea have been shown to largely contribute to the dietary intake of these antioxidants in several populations. More recently, the use of coffee leaves to produce tea has become a potential commercial target, therefore prompting studies on the quantification of polyphenols in coffee leaves. In this study a variety of coffee leaf species, at different development stages, were analyzed using ultra-high pressure liquid chromatography. The results demonstrate that both the botanical origin of the samples and their maturity influence significantly the concentration of the antioxidants; for total chlorogenic acids a two-fold difference was found between different species and up to a three-fold variation was observed between young and mature leaves. Furthermore, the range of concentrations of chlorogenic acids in young leaves (35.7\u201380.8 mg\/g of dry matter) were found to be comparable to the one reported for green coffee beans. The results provide important data from which potential new commercial products can be developed.<\/jats:p>","DOI":"10.3390\/antiox9010006","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T09:50:33Z","timestamp":1576835433000},"page":"6","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Dietary Antioxidants in Coffee Leaves: Impact of Botanical Origin and Maturity on Chlorogenic Acids and Xanthones"],"prefix":"10.3390","volume":"9","author":[{"given":"\u00c2ngelo","family":"Monteiro","sequence":"first","affiliation":[{"name":"Department of Chemistry, Queen Mary University of London, Mile End Road, London E1 4NS, UK"}]},{"given":"Silvia","family":"Colomban","sequence":"additional","affiliation":[{"name":"Illycaff\u00e8 S.p.A., via Flavia 143, 34100 Trieste, Italy"}]},{"given":"Helena G.","family":"Azinheira","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o das Ferrugens do Cafeeiro, Instituto Superior de Agronomia, Universidade de Lisboa, 2784-505 Oeiras, Portugal"},{"name":"Linking Landscape, Environment, Agricultural and Food, Instituto Superior de Agronomia, Universidade de Lisboa, 1349-017 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9676-1036","authenticated-orcid":false,"given":"Leonor","family":"Guerra-Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o das Ferrugens do Cafeeiro, Instituto Superior de Agronomia, Universidade de Lisboa, 2784-505 Oeiras, Portugal"},{"name":"Linking Landscape, Environment, Agricultural and Food, Instituto Superior de Agronomia, Universidade de Lisboa, 1349-017 Lisboa, Portugal"}]},{"given":"Maria","family":"Do C\u00e9u Silva","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o das Ferrugens do Cafeeiro, Instituto Superior de Agronomia, Universidade de Lisboa, 2784-505 Oeiras, Portugal"},{"name":"Linking Landscape, Environment, Agricultural and Food, Instituto Superior de Agronomia, Universidade de Lisboa, 1349-017 Lisboa, Portugal"}]},{"given":"Luciano","family":"Navarini","sequence":"additional","affiliation":[{"name":"Illycaff\u00e8 S.p.A., via Flavia 143, 34100 Trieste, Italy"}]},{"given":"Marina","family":"Resmini","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Queen Mary University of London, Mile End Road, London E1 4NS, UK"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1080\/10942912.2016.1220393","article-title":"Natural polyphenols: An overview","volume":"20","author":"Abbas","year":"2017","journal-title":"Int. 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