{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T06:04:00Z","timestamp":1777097040699,"version":"3.51.4"},"reference-count":77,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"COMPETE Operational Programme (COMPETE 2020) under the PORTUGAL 2020 Partnership Agreement through the European Regional Development Fund (ERDF)","award":["17777"],"award-info":[{"award-number":["17777"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Fruit enzymatic browning (EB) inhibition continues to be a challenge in the Food Industry. This physiological disorder results mainly from the oxidation of natural phenolic compounds by polyphenoloxidase (PPO) and peroxidase (POX) leading to the formation of brown pigments. EB can be controlled with the application of antioxidants, reducing\/inhibiting the activity of these oxidative enzymes. In this study, strawberry tree (leaves and branches) and apple byproduct were the natural-based extracts (NES) selected, as potential tissue browning inhibitors, within a first screening of fifteen natural-based extracts with antioxidant properties. Phenolic profile, total phenolic content and antioxidant activity of the selected extracts were also performed as well as their depletion effect on the oxidative enzyme\u2019s activity and browning inhibiton in fresh-cut pears. Strawberry tree extracts (leaves and branches) revealed higher total phenolic content (207.97 \u00b1 0.01 mg GAE.gNES\u22121 and 104.07 \u00b1 16.38 mg GAE.gNES\u22121, respectively), confirmed by the plethora of phenolic compounds identified by LC-ESI-UHR-QqTOF-HRMS and quantified by HPLC. This phytochemical composition was reflected in the low IC50 against PPO and POX obtained. Despite the lower phenolic content (6.76 \u00b1 0.11 mg GAE.gNES\u22121) and antioxidant activity (IC50 = 45.59 \u00b1 1.34 mg mL\u22121), apple byproduct extract showed potential in delaying browning. This study highlights the opportunity of byproducts and agricultural wastes extracts as novel anti-browning agents.<\/jats:p>","DOI":"10.3390\/antiox9080715","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T09:30:54Z","timestamp":1596792654000},"page":"715","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Natural-Based Antioxidant Extracts as Potential Mitigators of Fruit Browning"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9671-7844","authenticated-orcid":false,"given":"Cindy","family":"Dias","sequence":"first","affiliation":[{"name":"Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal"}]},{"given":"Alexandre M. A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"CICECO-Instituto de Materiais de Aveiro, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portuga"},{"name":"LAQV-REQUIMTE, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"Ana L.","family":"Amaro","sequence":"additional","affiliation":[{"name":"Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9051-8123","authenticated-orcid":false,"given":"Ana A.","family":"Vilas-Boas","sequence":"additional","affiliation":[{"name":"Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5445-1032","authenticated-orcid":false,"given":"Ana","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6749-7619","authenticated-orcid":false,"given":"Sonia A. O.","family":"Santos","sequence":"additional","affiliation":[{"name":"CICECO-Instituto de Materiais de Aveiro, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portuga"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5403-8416","authenticated-orcid":false,"given":"Armando J. D.","family":"Silvestre","sequence":"additional","affiliation":[{"name":"CICECO-Instituto de Materiais de Aveiro, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portuga"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0396-3019","authenticated-orcid":false,"given":"S\u00edlvia M.","family":"Rocha","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"N\u00e9lson","family":"Isidoro","sequence":"additional","affiliation":[{"name":"Cooperativa Agr\u00edcola dos Fruticultores do Cadaval, CRL (COOPVAL), Estrada Nacional 115, Km 26 2550-108 Cadaval, Portugal"}]},{"given":"Manuela","family":"Pintado","sequence":"additional","affiliation":[{"name":"Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua de Diogo Botelho, 1327, 4169-005 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.postharvbio.2016.06.010","article-title":"Phenolic extracts from wild edible plants to control postharvest diseases of sweet cherry fruit","volume":"120","author":"Gatto","year":"2016","journal-title":"Postharvest Biol. 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