{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:15:43Z","timestamp":1770743743796,"version":"3.49.0"},"reference-count":63,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"COMPETE Operational Programme (COMPETE 2020) under the PORTUGAL 2020","award":["Parceria n\u00ba 146\/ Iniciativa n\u00ba 341"],"award-info":[{"award-number":["Parceria n\u00ba 146\/ Iniciativa n\u00ba 341"]}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/50006\/2020"],"award-info":[{"award-number":["UIDB\/50006\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/ 50011\/2020"],"award-info":[{"award-number":["UIDB\/ 50011\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UIDP\/50011\/2020"],"award-info":[{"award-number":["UIDP\/50011\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Regional Development Fund - FEDER","award":["CENTRO-01-0145-FEDER-000001"],"award-info":[{"award-number":["CENTRO-01-0145-FEDER-000001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Sciences"],"abstract":"<jats:p>Elderberry (Sambucus nigra L.) consumption has been growing in the last years, generating a large number of stalks (~10% of the berries bunch) that are still under-valorized. This study focused on the evaluation of elderberry stalks as a source of high-value phytochemicals. In this vein, the essential mineral content and lipophilic composition were analyzed for the first time. In addition, the polar fraction was evaluated regarding its total phenolic content (TPC) and antioxidant activity by both 2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and 2-diphenyl-1-picrylhydrazyl hydrate (DPPH) assays. The lipophilic fraction was mainly composed of triterpenic acids (2902.20 mg kg\u22121 of dry weight (dw)), fatty acids (711.73 mg kg\u22121 dw) and sterols (288.56 mg kg\u22121 dw). Minor amounts of long-chain aliphatic alcohols and other components were also detected. Ursolic acid (2265.83 mg kg\u22121 dw), hexadecanoic acid (219.85 mg kg\u22121 dw) and \u03b2-sitosterol (202.74 mg kg\u22121 dw) were the major lipophilic components verified. The results of this study also indicated that elderberry stalks might be used as a natural source of essential minerals, particularly calcium, iron and potassium, which are known to play important roles in various body functions. The analysis of the polar fraction also showed that elderberry stalks present TPC as high as elderberry themselves as well as considerable antioxidant activity (1.04 and 0.37 mmol TE g\u22121 of extract, against respectively ABTS and DPPH radicals). These results highlight the potential of elderberry stalks as a natural source of high-value phytochemicals that may be explored in several fields.<\/jats:p>","DOI":"10.3390\/app12010382","type":"journal-article","created":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T20:49:38Z","timestamp":1641242978000},"page":"382","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Elderberry Stalks as a Source of High-Value Phytochemical: Essential Minerals and Lipophilic Compounds"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3157-3288","authenticated-orcid":false,"given":"Samuel","family":"Patinha","sequence":"first","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"CICECO-Aveiro Institute of Materials & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"Juliana V.","family":"Murteira","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3732-774X","authenticated-orcid":false,"given":"Carina Pedrosa","family":"Costa","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"\u00c2ngelo C.","family":"Salvador","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"CICECO-Aveiro Institute of Materials & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6749-7619","authenticated-orcid":false,"given":"S\u00f3nia A. O.","family":"Santos","sequence":"additional","affiliation":[{"name":"CICECO-Aveiro Institute of Materials & Department of Chemistry, Campus Universit\u00e1rio Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5403-8416","authenticated-orcid":false,"given":"Armando J. 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