{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T01:34:48Z","timestamp":1769218488212,"version":"3.49.0"},"reference-count":49,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T00:00:00Z","timestamp":1655942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Portuguese National Funds","award":["UIDB\/50006\/2020"],"award-info":[{"award-number":["UIDB\/50006\/2020"]}]},{"name":"Portuguese National Funds","award":["UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDB\/50017\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Sciences"],"abstract":"<jats:p>Limonium vulgare Mill. is a plant growing widely in harsh environments, such as salt marshes, for which a chemical profile is still unknown, although some interesting bioactivities were already reported. So, this halophyte chemical profile must be established to find the possible bioactive compounds, valorize the species, and contribute to the salt marsh\u2019s exploitation. This work set the chemical profile of L. vulgare\u2019s aerial parts (leaves and inflorescences) using UHPLC-DAD-ESI\/MS2 and GC-MS analysis. The lipophilic profile showed a richness in fatty acids, alkanes, and terpenoids, \u03b2-sitosterol being the major compound in inflorescences in the fruiting stage (0.822 \u00b1 0.015 mg\/g of the dry plant) and leaves (0.534 \u00b1 0.017 mg\/g of the dry plant). In contrast, in the inflorescences in the flowering stage, the major compound is nonacosane (0.228 \u00b1 0.001 mg\/g of the dry plant). The polyphenolic profile demonstrates that L. vulgare produces several flavonoids from which quercetin and myricetin can be highlighted; in particular, myricetin derivatives are prevalent in all extracts. Amongst the flavonoids, myricetin 3-rhamnoside is the most abundant in the inflorescences in the flowering stage (6.35 \u00b1 0.05 mg\/g of the dry plant), myricetin in leaves (9.69 \u00b1 0.11 mg\/g of the dry plant), and in the inflorescences in the fruiting stage baicalin presents the highest amount (5.15 \u00b1 0.07 mg\/g of the dry plant). This is the first report on L. vulgare\u2019s chemical profile and the results indicate that this species is an exciting source of bioactive compounds, suggesting it has a use to produce nutraceuticals and\/or pharmaceuticals.<\/jats:p>","DOI":"10.3390\/app12136384","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T21:25:00Z","timestamp":1656019500000},"page":"6384","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Chemical Profiling of Limonium\u00a0vulgare Mill. Using UHPLC-DAD-ESI\/MS2 and GC-MS Analysis"],"prefix":"10.3390","volume":"12","author":[{"given":"Benedict","family":"Carius","sequence":"first","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"Department of Chemical Engineering and Biotechnology, University of Applied Sciences, 64295 Darmstadt, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8060-2842","authenticated-orcid":false,"given":"Helena","family":"Silva","sequence":"additional","affiliation":[{"name":"CESAM & Department of Biology, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2861-8286","authenticated-orcid":false,"given":"Artur M. S.","family":"Silva","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4249-7089","authenticated-orcid":false,"given":"Diana C. G. A.","family":"Pinto","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE & Department of Chemistry, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"key":"ref_1","unstructured":"(2022, May 04). Plants of the World Online. Available online: https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:687035-1#descriptions."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Tuteja, N., and Gill, S.S. (2014). Climate Change and Plant Abiotic Stress Tolerance, Wiley-VCH Verlag GmbH & Co. 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