{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T09:12:47Z","timestamp":1774775567793,"version":"3.50.1"},"reference-count":51,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Sciences"],"abstract":"<jats:p>Artificial intelligence (AI) has emerged as a transformative technology in radiology, offering enhanced diagnostic accuracy, improved workflow efficiency and potential risk mitigation. However, its effectiveness in reducing clinical and occupational risks in radiology departments remains underexplored. This systematic review aimed to evaluate the current literature on AI applications in computed tomography (CT) radiology and their contributions to risk reduction. Following the PRISMA 2020 guidelines, a systematic search was conducted in PubMed, Scopus and Web of Science for studies published between 2021 and 2025 (the databases were last accessed on 15 April 2025). Thirty-four studies were included based on their relevance to AI in radiology and reported outcomes. Extracted data included study type, geographic region, AI application and type, role in clinical workflow, use cases, sensitivity and specificity. The majority of studies addressed triage (61.8%) and computer-aided detection (32.4%). AI was most frequently applied in chest imaging (47.1%) and brain haemorrhage detection (29.4%). The mean reported sensitivity was 89.0% and specificity was 93.3%. AI tools demonstrated advantages in image interpretation, automated patient positioning, prioritisation and measurement standardisation. Reported benefits included reduced cognitive workload, improved triage efficiency, decreased manual annotation and shorter exposure times. AI systems in CT radiology show strong potential to enhance diagnostic consistency and reduce occupational risks. The evidence supports the integration of AI-based tools to assist diagnosis, lower human workload and improve overall safety in radiology departments.<\/jats:p>","DOI":"10.3390\/app15179659","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T08:04:15Z","timestamp":1756886655000},"page":"9659","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Artificial Intelligence in Computed Tomography Radiology: A Systematic Review on Risk Reduction Potential"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0343-2937","authenticated-orcid":false,"given":"Sandra","family":"Coelho","sequence":"first","affiliation":[{"name":"Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5720-1554","authenticated-orcid":false,"given":"Al\u00e9xia","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Centre of Research, Education, Innovation and Intervention in Sport (CIFI2D), Porto Biomechanics Laboratory (LABIOMEP), Faculty of Sport, University of Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4514-9728","authenticated-orcid":false,"given":"Marco","family":"Freitas","sequence":"additional","affiliation":[{"name":"Radiology Department, School of Health, Polytechnic Institute of Porto, 4200-072 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5811-0443","authenticated-orcid":false,"given":"Ricardo J.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Centre of Research, Education, Innovation and Intervention in Sport (CIFI2D), Porto Biomechanics Laboratory (LABIOMEP), Faculty of Sport, University of Porto, 4200-450 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41568-018-0016-5","article-title":"Artificial Intelligence in Radiology","volume":"18","author":"Hosny","year":"2018","journal-title":"Nat. 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