{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T17:28:58Z","timestamp":1771867738352,"version":"3.50.1"},"reference-count":35,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T00:00:00Z","timestamp":1739059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bacteria"],"abstract":"<jats:p>This study explores the prevalence and antibiotic resistance of urinary tract infections (UTIs) in pregnant women in central Portugal. A retrospective observational study was conducted on 201 positive urine cultures from pregnant women at a hospital center between January 2018 and December 2022. The data collected included age, hospital admission source, history of antibiotic therapy, catheterization status, identity of bacterial isolates, and their antibiotic profile. The most common bacterial strains were Escherichia coli (52.4%) and Streptococcus agalactiae (16.9%). In terms of antibiotic resistance, Escherichia coli demonstrated complete sensitivity to ertapenem, while Streptococcus agalactiae showed sensitivity to four antibiotics, including trimethoprim\/sulfamethoxazole. Notably, most infections occurred in the third trimester, underscoring the need for continuous monitoring throughout pregnancy. This study emphasizes the importance of tailored treatment strategies to manage UTIs in pregnancy effectively, reducing the potential maternal and fetal complications. These findings contribute to regional data on UTI management in pregnant populations and aim to support improved healthcare practices. These regional data provide a solid foundation for optimizing healthcare practices in pregnant women, suggesting targeted approaches to combat antibiotic resistance and improve maternal\u2013fetal safety during UTI treatment.<\/jats:p>","DOI":"10.3390\/bacteria4010010","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T03:39:47Z","timestamp":1739158787000},"page":"10","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rising Trends of Urinary Infections Among Pregnant Women: Insights from a Portuguese Hospital (2018\u20132022)"],"prefix":"10.3390","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8405-4249","authenticated-orcid":false,"given":"Francisco","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Sport Physical Activity and Health Research & Innovation Center (Sprint), Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9862-0691","authenticated-orcid":false,"given":"Patr\u00edcia","family":"Coelho","sequence":"additional","affiliation":[{"name":"Sport Physical Activity and Health Research & Innovation Center (Sprint), Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5045-7477","authenticated-orcid":false,"given":"S\u00f3nia","family":"Mateus","sequence":"additional","affiliation":[{"name":"Sport Physical Activity and Health Research & Innovation Center (Sprint), Polytechnic Institute of Castelo Branco, 6000-084 Castelo Branco, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3226-9727","authenticated-orcid":false,"given":"Hatem","family":"Eideh","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, Al-Quds University, Abu Dis P144, Palestine"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9347-0535","authenticated-orcid":false,"given":"Teresa","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"FMUC\u2014Faculty of Medicine, University Coimbra, 3004-504 Coimbra, Portugal"},{"name":"CNC-UC\u2014Center for Neuroscience and Cell Biology, University Coimbra, 3004-504 Coimbra, Portugal"},{"name":"CIBB\u2014Centre for Innovative Biomedicine and Biotechnology, University Coimbra, 3004-504 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7844-0506","authenticated-orcid":false,"given":"Armando","family":"Caseiro","sequence":"additional","affiliation":[{"name":"School of Health, Polytechnic University of Coimbra, Rua da Miseric\u00f3rdia, Lagar dos Corti\u00e7os, S. Martinho do Bispo, 3045-093 Coimbra, Portugal"},{"name":"H&TRC\u2014Health & Technology Research Center, Coimbra Health School, Polytechnic University of Coimbra, Rua 5 de Outubro, 3045-043 Coimbra, Portugal"},{"name":"Faculty of Veterinary Medicine, University of Lisbon, CIPER, 1649-004 Cruz Quebrada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6191-5912","authenticated-orcid":false,"given":"Miguel","family":"Castelo Branco","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Beira Interior, 6201-001 Covilha, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e235","DOI":"10.2741\/1007","article-title":"Molecular epidemiology of Escherichia coli mediated urinary tract infections","volume":"8","author":"Zhang","year":"2003","journal-title":"Front. Biosci. J. 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