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Sci., 26.","DOI":"10.3390\/ijms26052069"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"9325","DOI":"10.1038\/s41598-022-13364-1","article-title":"Cdkl5 mutant zebrafish shows skeletal and neuronal alterations mimicking human CDKL5 deficiency disorder","volume":"12","author":"Varela","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Gastalho, C.M., Sena, A.M., L\u00f3pez, \u00d3., Fern\u00e1ndez-Bola\u00f1os, J.G., Garc\u00eda-Sosa, A.T., Pereira, F., Antunes, C.M., Costa, A.R., Burke, A.J., and Carreiro, E.P. (2024). Assessing the Potential of 1,2,3-Triazole-Dihydropyrimidinone Hybrids Against Cholinesterases: In Silico, In Vitro, and In Vivo Studies. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms252011153"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.freeradbiomed.2007.06.007","article-title":"Red wine-dependent reduction of nitrite to nitric oxide in the stomach","volume":"43","author":"Gago","year":"2007","journal-title":"Free. Radic. Biol. Med."},{"key":"ref_33","first-page":"2211","article-title":"Do oral and gut microbiota communicate through redox pathways? A novel asset of the nitrate-nitrite-NO pathway","volume":"598","author":"Paiva","year":"2024","journal-title":"FEBS Lett."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Ortega, M.B., Aparicio, E., Gri\u00f1\u00e1n-Lis\u00f3n, C., Jim\u00e9nez, G., L\u00f3pez-Ruiz, E., Palacios, J.L., Ruiz-Alcal\u00e1, G., Alba, C., Mart\u00ednez, A., and Boulaiz, H. (2023). Interferon-Alpha Decreases Cancer Stem Cell Properties and Modulates Exosomes in Malignant Melanoma. 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