{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T09:37:30Z","timestamp":1769765850075,"version":"3.49.0"},"reference-count":15,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T00:00:00Z","timestamp":1679616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the European Union\u2019s Horizon Europe research and innovation programme","award":["101057389"],"award-info":[{"award-number":["101057389"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Breast cancer conservative treatment (BCCT) is a form of treatment commonly used for patients with early breast cancer. This procedure consists of removing the cancer and a small margin of surrounding tissue, while leaving the healthy tissue intact. In recent years, this procedure has become increasingly common due to identical survival rates and better cosmetic outcomes than other alternatives. Although significant research has been conducted on BCCT, there is no gold-standard for evaluating the aesthetic results of the treatment. Recent works have proposed the automatic classification of cosmetic results based on breast features extracted from digital photographs. The computation of most of these features requires the representation of the breast contour, which becomes key to the aesthetic evaluation of BCCT. State-of-the-art methods use conventional image processing tools that automatically detect breast contours based on the shortest path applied to the Sobel filter result in a 2D digital photograph of the patient. However, because the Sobel filter is a general edge detector, it treats edges indistinguishably, i.e., it detects too many edges that are not relevant to breast contour detection and too few weak breast contours. In this paper, we propose an improvement to this method that replaces the Sobel filter with a novel neural network solution to improve breast contour detection based on the shortest path. The proposed solution learns effective representations for the edges between the breasts and the torso wall. We obtain state of the art results on a dataset that was used for developing previous models. Furthermore, we tested these models on a new dataset that contains more variable photographs and show that this new approach shows better generalization capabilities as the previously developed deep models do not perform so well when faced with a different dataset for testing. The main contribution of this paper is to further improve the capabilities of models that perform the objective classification of BCCT aesthetic results automatically by improving upon the current standard technique for detecting breast contours in digital photographs. To that end, the models introduced are simple to train and test on new datasets which makes this approach easily reproducible.<\/jats:p>","DOI":"10.3390\/bioengineering10040401","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T06:34:07Z","timestamp":1679639647000},"page":"401","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Deep Edge Detection Methods for the Automatic Calculation of the Breast Contour"],"prefix":"10.3390","volume":"10","author":[{"given":"Nuno","family":"Freitas","sequence":"first","affiliation":[{"name":"Faculdade de Engenharia, Universidade do Porto, 4099-002 Porto, Portugal"},{"name":"INESC TEC, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9792-3887","authenticated-orcid":false,"given":"Daniel","family":"Silva","sequence":"additional","affiliation":[{"name":"Faculdade de Engenharia, Universidade do Porto, 4099-002 Porto, Portugal"},{"name":"INESC TEC, 4200-465 Porto, Portugal"}]},{"given":"Carlos","family":"Mavioso","sequence":"additional","affiliation":[{"name":"Breast Unit, Champalimaud Foundation, 1400-038 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8137-3700","authenticated-orcid":false,"given":"Maria J.","family":"Cardoso","sequence":"additional","affiliation":[{"name":"INESC TEC, 4200-465 Porto, Portugal"},{"name":"Breast Unit, Champalimaud Foundation, 1400-038 Lisbon, Portugal"},{"name":"Faculty of Medicine, University of Lisbon, 1649-004 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3760-2473","authenticated-orcid":false,"given":"Jaime S.","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Faculdade de Engenharia, Universidade do Porto, 4099-002 Porto, Portugal"},{"name":"INESC TEC, 4200-465 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3322\/caac.21763","article-title":"Cancer statistics, 2023","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2174\/1573405611309010006","article-title":"Methods for the Aesthetic Evaluation of Breast Cancer Conservation Treatment: A Technological Review","volume":"9","author":"Oliveira","year":"2013","journal-title":"Curr. Med. Imaging Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0360-3016(79)90729-6","article-title":"Analysis of cosmetic results following primary radiation therapy for stages I and II carcinoma of the breast","volume":"5","author":"Harris","year":"1979","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.breast.2007.01.013","article-title":"The use of a breast symmetry index for objective evaluation of breast cosmesis","volume":"16","author":"Fitzal","year":"2007","journal-title":"Breast (Edinb. Scotl.)"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.artmed.2007.02.007","article-title":"Towards an intelligent medical system for the aesthetic evaluation of breast cancer conservative treatment","volume":"40","author":"Cardoso","year":"2007","journal-title":"Artif. Intell. Med."},{"key":"ref_6","unstructured":"Cardoso, M.J., and Cardoso, J. (2008, January 28\u201331). Automatic breast contour detection in digital photographs. Proceedings of the First International Conference on Health Informatics, HEALTHINF 2008, Funchal, Madeira, Portugal."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF01386390","article-title":"A note on two problems in connexion with graphs","volume":"1","author":"Dijkstra","year":"1959","journal-title":"Numer. Math."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Sousa, R., Cardoso, J.S., Pinto da Costa, J.F., and Cardoso, M.J. (2008, January 12\u201315). Breast contour detection with shape priors. Proceedings of the 2008 15th IEEE International Conference on Image Processing, San Diego, CA, USA.","DOI":"10.1109\/ICIP.2008.4712036"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Silva, W., Castro, E., Cardoso, M.J., Fitzal, F., and Cardoso, J.S. (2019, January 8\u201311). Deep Keypoint Detection for the Aesthetic Evaluation of Breast Cancer Surgery Outcomes. Proceedings of the 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), Venice, Italy.","DOI":"10.1109\/ISBI.2019.8759331"},{"key":"ref_10","unstructured":"Simonyan, K., and Zisserman, A. (2014). Very deep convolutional networks for large-scale image recognition. arXiv."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s12553-020-00423-8","article-title":"A novel approach to keypoint detection for the aesthetic evaluation of breast cancer surgery outcomes","volume":"10","author":"Silva","year":"2020","journal-title":"Health Technol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Zhou, Z., Siddiquee, M.M.R., Tajbakhsh, N., and Liang, J. (2018). UNet++: A Nested U-Net Architecture for Medical Image Segmentation. arXiv.","DOI":"10.1007\/978-3-030-00889-5_1"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Pu, M., Huang, Y., Guan, Q., and Ling, H. (2021, January 11\u201317). Rindnet: Edge detection for discontinuity in reflectance, illumination, normal and depth. Proceedings of the IEEE\/CVF International Conference on Computer Vision, Montreal, BC, Canada.","DOI":"10.1109\/ICCV48922.2021.00680"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Sun, R., Lei, T., Chen, Q., Wang, Z., Du, X., Zhao, W., and Nandi, A.K. (2022). Survey of Image Edge Detection. Front. Signal Process., 2.","DOI":"10.3389\/frsip.2022.826967"},{"key":"ref_15","unstructured":"Osanlou, K., Guettier, C., Bursuc, A., Cazenave, T., and Jacopin, E. (2021). Constrained Shortest Path Search with Graph Convolutional Neural Networks. arXiv."}],"container-title":["Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-5354\/10\/4\/401\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:02:17Z","timestamp":1760122937000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-5354\/10\/4\/401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,24]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["bioengineering10040401"],"URL":"https:\/\/doi.org\/10.3390\/bioengineering10040401","relation":{},"ISSN":["2306-5354"],"issn-type":[{"value":"2306-5354","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,24]]}}}