{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:17:06Z","timestamp":1777947426463,"version":"3.51.4"},"reference-count":169,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Portuguese Foundation for Science and Technology","award":["SFRH\/BD\/77823\/2011"],"award-info":[{"award-number":["SFRH\/BD\/77823\/2011"]}]},{"name":"Portuguese Foundation for Science and Technology","award":["UIDB\/04539\/2020"],"award-info":[{"award-number":["UIDB\/04539\/2020"]}]},{"name":"Portuguese Foundation for Science and Technology","award":["UIDB\/04033\/2020"],"award-info":[{"award-number":["UIDB\/04033\/2020"]}]},{"name":"Portuguese Foundation for Science and Technology","award":["LA\/P\/0126\/2020"],"award-info":[{"award-number":["LA\/P\/0126\/2020"]}]},{"name":"CNC","award":["SFRH\/BD\/77823\/2011"],"award-info":[{"award-number":["SFRH\/BD\/77823\/2011"]}]},{"name":"CNC","award":["UIDB\/04539\/2020"],"award-info":[{"award-number":["UIDB\/04539\/2020"]}]},{"name":"CNC","award":["UIDB\/04033\/2020"],"award-info":[{"award-number":["UIDB\/04033\/2020"]}]},{"name":"CNC","award":["LA\/P\/0126\/2020"],"award-info":[{"award-number":["LA\/P\/0126\/2020"]}]},{"name":"CITAB","award":["SFRH\/BD\/77823\/2011"],"award-info":[{"award-number":["SFRH\/BD\/77823\/2011"]}]},{"name":"CITAB","award":["UIDB\/04539\/2020"],"award-info":[{"award-number":["UIDB\/04539\/2020"]}]},{"name":"CITAB","award":["UIDB\/04033\/2020"],"award-info":[{"award-number":["UIDB\/04033\/2020"]}]},{"name":"CITAB","award":["LA\/P\/0126\/2020"],"award-info":[{"award-number":["LA\/P\/0126\/2020"]}]},{"name":"Inov4Agro","award":["SFRH\/BD\/77823\/2011"],"award-info":[{"award-number":["SFRH\/BD\/77823\/2011"]}]},{"name":"Inov4Agro","award":["UIDB\/04539\/2020"],"award-info":[{"award-number":["UIDB\/04539\/2020"]}]},{"name":"Inov4Agro","award":["UIDB\/04033\/2020"],"award-info":[{"award-number":["UIDB\/04033\/2020"]}]},{"name":"Inov4Agro","award":["LA\/P\/0126\/2020"],"award-info":[{"award-number":["LA\/P\/0126\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>Since its first description in the late 1930s, Q fever has raised many questions. Coxiella burnetii, the causative agent, is a zoonotic pathogen affecting a wide range of hosts. This airborne organism leads to an obligate, intracellular lifecycle, during which it multiplies in the mononuclear cells of the immune system and in the trophoblasts of the placenta in pregnant females. Although some issues about C. burnetii and its pathogenesis in animals remain unclear, over the years, some experimental studies on Q fever have been conducted in goats given their excretion pattern. Goats play an important role in the epidemiology and economics of C. burnetii infections, also being the focus of several epidemiological studies. Additionally, variants of the agent implicated in human long-term disease have been found circulating in goats. The purpose of this review is to summarize the latest research on C. burnetii infection and the role played by goats in the transmission of the infection to humans.<\/jats:p>","DOI":"10.3390\/biology11121703","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T02:29:23Z","timestamp":1669343363000},"page":"1703","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Role of Goats in the Epidemiology of Coxiella burnetii"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0916-2044","authenticated-orcid":false,"given":"Sofia","family":"Anast\u00e1cio","sequence":"first","affiliation":[{"name":"Vasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Vasco da Gama University School, Avenida Jos\u00e9 R. Sousa Fernandes 197 Lordem\u00e3o, 3020-210 Coimbra, Portugal"},{"name":"Center of Neurosciences and Cell Biology, Health Science Campus, 3000-548 Coimbra, Portugal"}]},{"given":"S\u00e9rgio Ramalho","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Vasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Vasco da Gama University School, Avenida Jos\u00e9 R. Sousa Fernandes 197 Lordem\u00e3o, 3020-210 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7492-4965","authenticated-orcid":false,"given":"Maria Jos\u00e9","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Laboratory Medical Microbiology\u2014Antimicrobials, Biocides and Biofilms Unit, Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Tr\u00e1s-os-Montes e Alto Douro, Quinta de Prados, 5000-801 Vila Real, Portugal"},{"name":"Centre for the Research and Technology Agro-Environmental and Biological Sciences and Inov4Agro\u2014Institute for Innovation, Capacity Building and Sustainability of Agri-Food Production, 5000-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-8540","authenticated-orcid":false,"given":"Gabriela Jorge","family":"da Silva","sequence":"additional","affiliation":[{"name":"Center of Neurosciences and Cell Biology, Health Science Campus, 3000-548 Coimbra, Portugal"},{"name":"Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.5694\/j.1326-5377.1937.tb43743.x","article-title":"\u201cQ\u201d fever, a new fever entity: Clinical features, diagnosis and laboratory investigation","volume":"2","author":"Derrick","year":"1937","journal-title":"Med. 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