{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:52:40Z","timestamp":1775818360006,"version":"3.50.1"},"reference-count":242,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Portuguese Science Foundation","doi-asserted-by":"publisher","award":["PTDC\/EME-EME\/1239\/2021"],"award-info":[{"award-number":["PTDC\/EME-EME\/1239\/2021"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Science Foundation","doi-asserted-by":"publisher","award":["UIDB\/00481\/2020"],"award-info":[{"award-number":["UIDB\/00481\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Science Foundation","doi-asserted-by":"publisher","award":["UIDP\/00481\/2020"],"award-info":[{"award-number":["UIDP\/00481\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Portuguese Science Foundation","doi-asserted-by":"publisher","award":["CENTRO-01-0145-FEDER-022083"],"award-info":[{"award-number":["CENTRO-01-0145-FEDER-022083"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Portugal Regional Operational Programme (Centro2020)","award":["PTDC\/EME-EME\/1239\/2021"],"award-info":[{"award-number":["PTDC\/EME-EME\/1239\/2021"]}]},{"name":"Portugal Regional Operational Programme (Centro2020)","award":["UIDB\/00481\/2020"],"award-info":[{"award-number":["UIDB\/00481\/2020"]}]},{"name":"Portugal Regional Operational Programme (Centro2020)","award":["UIDP\/00481\/2020"],"award-info":[{"award-number":["UIDP\/00481\/2020"]}]},{"name":"Portugal Regional Operational Programme (Centro2020)","award":["CENTRO-01-0145-FEDER-022083"],"award-info":[{"award-number":["CENTRO-01-0145-FEDER-022083"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>The biomechanics of traumatic injuries of the human body as a consequence of road crashes, falling, contact sports, and military environments have been studied for decades. In particular, traumatic brain injury (TBI), the so-called \u201csilent epidemic\u201d, is the traumatic insult responsible for the greatest percentage of death and disability, justifying the relevance of this research topic. Despite its great importance, only recently have research groups started to seriously consider the sex differences regarding the morphology and physiology of women, which differs from men and may result in a specific outcome for a given traumatic event. This work aims to provide a summary of the contributions given in this field so far, from clinical reports to numerical models, covering not only the direct injuries from inertial loading scenarios but also the role sex plays in the conditions that precede an accident, and post-traumatic events, with an emphasis on neuroendocrine dysfunctions and chronic traumatic encephalopathy. A review on finite element head models and finite element neck models for the study of specific traumatic events is also performed, discussing whether sex was a factor in validating them. Based on the information collected, improvement perspectives and future directions are discussed.<\/jats:p>","DOI":"10.3390\/biology12010083","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T04:28:17Z","timestamp":1672806497000},"page":"83","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Biomechanics of Traumatic Head and Neck Injuries on Women: A State-of-the-Art Review and Future Directions"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2007-5988","authenticated-orcid":false,"given":"Gustavo P.","family":"Carmo","sequence":"first","affiliation":[{"name":"Centre for Mechanical Technology and Automation (TEMA), Department of Mechanical Engineering, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"given":"Jeroen","family":"Grigioni","sequence":"additional","affiliation":[{"name":"Centre for Mechanical Technology and Automation (TEMA), Department of Mechanical Engineering, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9751-8807","authenticated-orcid":false,"given":"F\u00e1bio A. O.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Centre for Mechanical Technology and Automation (TEMA), Department of Mechanical Engineering, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"LASI\u2014Intelligent Systems Associate Laboratory, 4800-058 Guimaraes, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5848-6424","authenticated-orcid":false,"given":"Ricardo J.","family":"Alves de Sousa","sequence":"additional","affiliation":[{"name":"Centre for Mechanical Technology and Automation (TEMA), Department of Mechanical Engineering, Campus Universit\u00e1rio de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"LASI\u2014Intelligent Systems Associate Laboratory, 4800-058 Guimaraes, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.3171\/2017.10.JNS17352","article-title":"Estimating the global incidence of traumatic brain injury","volume":"130","author":"Dewan","year":"2019","journal-title":"J. Neurosurg. JNS"},{"key":"ref_2","unstructured":"Johns Hopkins Medicine (2022, November 18). Traumatic Brain Injury. Available online: https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/traumatic-brain-injury."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1097\/HTR.0000000000000652","article-title":"Understanding Traumatic Brain Injury in Females: A State-of-the-Art Summary and Future Directions","volume":"36","author":"Valera","year":"2021","journal-title":"J. Head Trauma Rehabil."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.annepidem.2013.07.022","article-title":"Incidence of sport-related traumatic brain injury and risk factors of severity: A population-based epidemiologic study","volume":"23","author":"Selassie","year":"2013","journal-title":"Ann. Epidemiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1159\/000505424","article-title":"Incidence of sports-related traumatic brain injury of all severities: A systematic review","volume":"54","author":"Theadom","year":"2020","journal-title":"Neuroepidemiology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.aap.2005.08.001","article-title":"Incidence and risk factors of severe traumatic brain injury resulting from road accidents: A population-based study","volume":"38","author":"Javouhey","year":"2006","journal-title":"Accid. Anal. Prev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6609a1","article-title":"Traumatic brain injury-related emergency department visits, hospitalizations, and deaths\u2014United States, 2007 and 2013","volume":"66","author":"Taylor","year":"2017","journal-title":"MMWR Surveill. Summ."},{"key":"ref_8","unstructured":"Smith, S.G., Basile, K.C., Gilbert, L.K., Merrick, M.T., Patel, N., Walling, M., and Jain, A. (2017). National Intimate Partner and Sexual Violence Survey (NISVS): 2010\u20132012 State Report."},{"key":"ref_9","unstructured":"Centers for Disease Control and Prevention (2022, November 18). Intimate Partner Violence, Available online: https:\/\/www.cdc.gov\/violenceprevention\/intimatepartnerviolence\/index.html."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/FCH.0000000000000094","article-title":"Intimate partner violence and traumatic brain injury","volume":"39","author":"Schminkey","year":"2016","journal-title":"Fam. Community Health"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/026990596124719","article-title":"Incidence of mild and moderate brain injury in the United States, 1991","volume":"10","author":"Sosin","year":"1996","journal-title":"Brain Inj."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"110664","DOI":"10.1016\/j.jpsychores.2021.110664","article-title":"Turning away from sound: The role of fear avoidance in noise sensitivity following mild traumatic brain injury","volume":"151","author":"Faulkner","year":"2021","journal-title":"J. Psychosom. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"101563","DOI":"10.1016\/j.smrv.2021.101563","article-title":"Prevalence of insomnia and insomnia symptoms following mild-traumatic brain injury: A systematic review and meta-analysis","volume":"61","author":"Montgomery","year":"2022","journal-title":"Sleep Med. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e273","DOI":"10.1016\/j.wneu.2022.03.010","article-title":"Hypertension and Advanced Age Increase the Risk of Cognitive Impairment after Mild Traumatic Brain Injury: A Registry-Based Study","volume":"162","author":"Ozono","year":"2022","journal-title":"World Neurosurg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"107080","DOI":"10.1016\/j.clineuro.2021.107080","article-title":"Structural changes in retina (Retinal nerve fiber layer) following mild traumatic brain injury and its association with development of visual field defects","volume":"212","author":"Das","year":"2022","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"110117","DOI":"10.1016\/j.ejrad.2021.110117","article-title":"A systematic review and data synthesis of longitudinal changes in white matter integrity after mild traumatic brain injury assessed by diffusion tensor imaging in adults","volume":"147","author":"Kim","year":"2022","journal-title":"Eur. J. Radiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"100327","DOI":"10.1016\/j.bbih.2021.100327","article-title":"Short review: The impact of sex on neuroimmune and cognitive outcomes after traumatic brain injury","volume":"16","author":"Krukowski","year":"2021","journal-title":"Brain Behav. Immun.-Health"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"114022","DOI":"10.1016\/j.expneurol.2022.114022","article-title":"Sex-specific cognitive effects of mild traumatic brain injury to the frontal and temporal lobes","volume":"352","author":"Izchak","year":"2022","journal-title":"Exp. Neurol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1089\/neu.2018.6171","article-title":"Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know","volume":"36","author":"Gupte","year":"2019","journal-title":"J. Neurotrauma"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ejpain.2011.06.002","article-title":"Are there gender differences in coping with neck pain following acute whiplash trauma? A 12-month follow-up study","volume":"16","author":"Carstensen","year":"2012","journal-title":"Eur. J. Pain"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.iatssr.2013.04.001","article-title":"The risk of whiplash-induced medical impairment in rear-end impacts for males and females in driver seat compared to front passenger seat","volume":"37","author":"Jonsson","year":"2013","journal-title":"IATSS Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"101293","DOI":"10.1016\/j.jth.2021.101293","article-title":"Influential crash conditions leading to injury differences experienced by female and male drivers","volume":"24","author":"Ryan","year":"2022","journal-title":"J. Transp. Health"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Bhushan, R., Ravichandiran, V., and Kumar, N. (2022). 1\u2014An overview of the anatomy and physiology of the brain. Nanocarriers for Drug-Targeting Brain Tumors, Elsevier. Micro and Nano Technologies.","DOI":"10.1016\/B978-0-323-90773-6.00023-3"},{"key":"ref_24","unstructured":"Paulsen, F.J.W. (2018). Sobotta: Atlas of Anatomy, Urban & Fischer."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Forstmann, B.U., Keuken, M.C., and Alkemade, A. (2015). An Introduction to Human Brain Anatomy. An Introduction to Model-Based Cognitive Neuroscience, Springer.","DOI":"10.1007\/978-1-4939-2236-9_4"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40673-018-0087-9","article-title":"The mystery of the cerebellum: Clues from experimental and clinical observations","volume":"5","author":"Lawrenson","year":"2018","journal-title":"Cerebellum Ataxias"},{"key":"ref_27","first-page":"192","article-title":"The action potential","volume":"7","author":"Barnett","year":"2007","journal-title":"Pract. Neurol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1177\/1073858409341973","article-title":"Electrogenic tuning of the axon initial segment","volume":"15","author":"Clark","year":"2009","journal-title":"Neuroscientist"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nrn2631","article-title":"Microtubule assembly, organization and dynamics in axons and dendrites","volume":"10","author":"Conde","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1016\/j.bpj.2015.10.020","article-title":"Tau-ism: The Yin and Yang of Microtubule Sliding, Detachment, and Rupture","volume":"109","author":"Kuhl","year":"2015","journal-title":"Biophys. J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"7501","DOI":"10.1073\/pnas.1504081112","article-title":"Tau stabilizes microtubules by binding at the interface between tubulin heterodimers","volume":"112","author":"Kadavath","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cobme.2017.02.003","article-title":"Molecular mechanisms of chronic traumatic encephalopathy","volume":"1","author":"Kuhl","year":"2017","journal-title":"Curr. Opin. Biomed. Eng."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"E6416","DOI":"10.1073\/pnas.1513172112","article-title":"Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules","volume":"112","author":"Chung","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1007\/s00018-016-2216-z","article-title":"Role of tau in the spatial organization of axonal microtubules: Keeping parallel microtubules evenly distributed despite macromolecular crowding","volume":"73","author":"Boca","year":"2016","journal-title":"Cell Mol. Life Sci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"R677","DOI":"10.1016\/j.cub.2015.06.020","article-title":"Coordinating Neuronal actin-Microtubule Dynamics","volume":"25","author":"Coles","year":"2015","journal-title":"Curr. Biol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"980","DOI":"10.3389\/fneur.2019.00980","article-title":"Tau Pathology in Chronic Traumatic Encephalopathy and Alzheimer\u2019s Disease: Similarities and Differences","volume":"10","author":"Katsumoto","year":"2019","journal-title":"Front. Neurol."},{"key":"ref_37","unstructured":"Graham, D., Gennarelli, T., and McIntosh, T. (2002). Greenfields neuropathology. Greenfields Neuropathology, Greenfield."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s11102-005-3463-4","article-title":"High Risk of Hypogonadism After Traumatic Brain Injury: Clinical Implications","volume":"8","author":"Agha","year":"2005","journal-title":"Pituitary"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00401-015-1515-z","article-title":"The first NINDS\/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy","volume":"131","author":"McKee","year":"2016","journal-title":"Acta Neuropathol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"29069","DOI":"10.1073\/pnas.2008306117","article-title":"Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction","volume":"117","author":"Braun","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00401-016-1649-7","article-title":"Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain","volume":"133","author":"Shively","year":"2017","journal-title":"Acta Neuropathol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/jnen\/nlx101","article-title":"Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies","volume":"77","author":"Kenney","year":"2017","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/nrn.2015.1","article-title":"Tau in physiology and pathology","volume":"17","author":"Wang","year":"2016","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/brain\/aws307","article-title":"The spectrum of disease in chronic traumatic encephalopathy","volume":"136","author":"McKee","year":"2013","journal-title":"Brain"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neubiorev.2013.12.004","article-title":"A meta-analysis of sex differences in human brain structure","volume":"39","author":"Ruigrok","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1007\/s10439-015-1312-9","article-title":"Emerging Brain Morphologies from Axonal Elongation","volume":"43","author":"Holland","year":"2015","journal-title":"Ann. Biomed. Eng."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1016\/j.bpj.2015.09.010","article-title":"Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury","volume":"109","author":"Ahmadzadeh","year":"2015","journal-title":"Biophys. J."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1096\/fj.09-142844","article-title":"Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration","volume":"24","author":"Patel","year":"2010","journal-title":"FASEB J."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/nrneurol.2013.29","article-title":"Chronic neuropathologies of single and repetitive TBI: Substrates of dementia?","volume":"9","author":"Smith","year":"2013","journal-title":"Nat. Rev. Neurol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.expneurol.2012.01.013","article-title":"Axonal pathology in traumatic brain injury","volume":"246","author":"Johnson","year":"2013","journal-title":"Exp. Neurol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.tins.2008.11.007","article-title":"Tau pathophysiology in neurodegeneration: A tangled issue","volume":"32","author":"Stoothoff","year":"2009","journal-title":"Trends Neurosci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.neuron.2011.04.009","article-title":"The Many Faces of Tau","volume":"70","author":"Morris","year":"2011","journal-title":"Neuron"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1474-4422(13)70090-5","article-title":"Tau pathology and neurodegeneration","volume":"12","author":"Spillantini","year":"2013","journal-title":"Lancet Neurol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.actbio.2016.07.040","article-title":"Brain stiffness increases with myelin content","volume":"42","author":"Weickenmeier","year":"2016","journal-title":"Acta Biomater."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jmbbm.2015.02.024","article-title":"Mechanical properties of gray and white matter brain tissue by indentation","volume":"46","author":"Budday","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/brain\/aww317","article-title":"Computational modelling of traumatic brain injury predicts the location of chronic traumatic encephalopathy pathology","volume":"140","author":"Ghajari","year":"2017","journal-title":"Brain"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1097\/NEN.0b013e3181a9d503","article-title":"Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury","volume":"68","author":"McKee","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/bpa.12248","article-title":"The neuropathology of chronic traumatic encephalopathy","volume":"25","author":"McKee","year":"2015","journal-title":"Brain Pathol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1146\/annurev-clinpsy-032814-112814","article-title":"Chronic traumatic encephalopathy: Historical origins and current perspective","volume":"11","author":"Montenigro","year":"2015","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1089\/0897715041269713","article-title":"Occurrence of pituitary dysfunction following traumatic brain injury","volume":"21","author":"Bondanelli","year":"2004","journal-title":"J. Neurotrauma"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1089\/neu.2005.22.937","article-title":"Anterior pituitary hormone abnormalities following traumatic brain injury","volume":"22","author":"Schneider","year":"2005","journal-title":"J. Neurotrauma"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1365-2265.2007.03020.x","article-title":"Predictors of anterior pituitary insufficiency after traumatic brain injury","volume":"68","author":"Schneider","year":"2008","journal-title":"Clin. Endocrinol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s11102-019-00958-8","article-title":"Pituitary pathology in traumatic brain injury: A review","volume":"22","author":"Sav","year":"2019","journal-title":"Pituitary"},{"key":"ref_64","first-page":"1080","article-title":"Chronic hypopituitarism after traumatic brain injury: Risk assessment and relationship to outcome","volume":"62","author":"Bavisetty","year":"2008","journal-title":"Neurosurgery"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3389\/fendo.2018.00176","article-title":"Neuroendocrine Abnormalities Following Traumatic Brain Injury: An Important Contributor to Neuropsychiatric Sequelae","volume":"9","author":"Molaie","year":"2018","journal-title":"Front. Endocrinol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1089\/neu.2007.0486","article-title":"Injury severity differentially affects short- and long-term neuroendocrine outcomes of traumatic brain injury","volume":"25","author":"Taylor","year":"2008","journal-title":"J. Neurotrauma"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1210\/jc.2007-0808","article-title":"Autoimmune hypophysitis: An underestimated disease in search of its autoantigen(s)","volume":"92","author":"Caturegli","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_68","first-page":"950","article-title":"The effect of gender on patients with moderate to severe head injuries","volume":"67","author":"Berry","year":"2009","journal-title":"J. Trauma"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1080\/00222930500219258","article-title":"Prediction of long-term occupational performance outcomes for adults after moderate to severe traumatic brain injury","volume":"28","author":"Devitt","year":"2006","journal-title":"Disabil. Rehabil."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1080\/026990598122197","article-title":"Female TBI patients recover better than males","volume":"12","author":"Groswasser","year":"1998","journal-title":"Brain Inj."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1080\/09602010903250928","article-title":"Does gender influence cognitive outcome after traumatic brain injury?","volume":"20","author":"Moore","year":"2010","journal-title":"Neuropsychol. Rehabil."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1097\/TA.0000000000001118","article-title":"Sex differences in mortality following isolated traumatic brain injury among older adults","volume":"81","author":"Albrecht","year":"2016","journal-title":"J. Trauma Acute Care Surg."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.wneu.2015.12.012","article-title":"Predictors of Outcomes in Traumatic Brain Injury","volume":"90","author":"Baum","year":"2016","journal-title":"World Neurosurg."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1097\/01.TA.0000058314.31655.5F","article-title":"Does sexual dimorphism influence outcome of traumatic brain injury patients? The answer is no!","volume":"54","author":"Coimbra","year":"2003","journal-title":"J. Trauma"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1089\/neu.2006.23.140","article-title":"Traumatic brain injury outcomes in pre- and post- menopausal females versus age-matched males","volume":"23","author":"Davis","year":"2006","journal-title":"J. Neurotrauma"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1089\/neu.2006.0028","article-title":"Prognostic value of demographic characteristics in traumatic brain injury: Results from the IMPACT study","volume":"24","author":"Mushkudiani","year":"2007","journal-title":"J. Neurotrauma"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/02688690600682259","article-title":"Investigating gender differences in outcome following severe traumatic brain injury in a predominantly Asian population","volume":"20","author":"Ng","year":"2006","journal-title":"Br. J. Neurosurg."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1016\/j.apmr.2005.06.018","article-title":"Outcome of a Comprehensive Neurorehabilitation Program for Patients With Traumatic Brain Injury","volume":"86","author":"Sarajuuri","year":"2005","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_79","first-page":"376","article-title":"Sex differences in injury severity and outcome measures after traumatic brain injury11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with which the author(s) is\/are affiliated","volume":"85","author":"Green","year":"2004","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1136\/jnnp.2008.147983","article-title":"Towards an understanding of sex differences in functional outcome following moderate to severe traumatic brain injury: A systematic review","volume":"79","author":"Baguley","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1080\/02699050903200530","article-title":"Sex differences in the long-term neuropsychological outcome of mild traumatic brain injury","volume":"23","author":"Tsushima","year":"2009","journal-title":"Brain Inj."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3171\/jns.2000.93.4.0539","article-title":"Do women fare worse: A metaanalysis of gender differences in traumatic brain injury outcome","volume":"93","author":"Farace","year":"2000","journal-title":"J. Neurosurg."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1177\/1099800404263050","article-title":"Is there a sex difference in the course following traumatic brain injury?","volume":"5","author":"Kirkness","year":"2004","journal-title":"Biol. Res. Nurs."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.3171\/foc.2000.8.1.156","article-title":"The independent effect of gender on outcomes following traumatic brain injury: A preliminary investigation","volume":"8","author":"Kraus","year":"2000","journal-title":"Neurosurg. Focus"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.amjsurg.2008.09.008","article-title":"Severe traumatic brain injury: Is there a gender difference in mortality?","volume":"197","author":"Ottochian","year":"2009","journal-title":"Am. J. Surg."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.injury.2007.08.028","article-title":"Gender differences in outcome in patients with hypotension and severe traumatic brain injury","volume":"39","author":"Ponsford","year":"2008","journal-title":"Injury"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.injury.2014.10.064","article-title":"Health-related quality of life after mild, moderate and severe traumatic brain injury: Patterns and predictors of suboptimal functioning during the first year after injury","volume":"46","author":"Scholten","year":"2015","journal-title":"Injury"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/HTR.0b013e3181c8f8e7","article-title":"Predictors of psychiatric disorders following traumatic brain injury","volume":"25","author":"Ponsford","year":"2010","journal-title":"J. Head Trauma Rehabil."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neuroimage.2017.04.029","article-title":"Individual differences in the dominance of interhemispheric connections predict cognitive ability beyond sex and brain size","volume":"155","author":"Martinez","year":"2017","journal-title":"Neuroimage"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.neuroimage.2014.09.035","article-title":"Sex differences in neocortical structure and cognitive performance: A surface-based morphometry study","volume":"104","author":"Escorial","year":"2015","journal-title":"Neuroimage"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1097\/01.wnr.0000227987.77304.cc","article-title":"Gender effects on callosal thickness in scaled and unscaled space","volume":"17","author":"Luders","year":"2006","journal-title":"Neuroreport"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0197-4580(94)90070-1","article-title":"Human corpus callosum in aging and Alzheimer\u2019s disease: A magnetic resonance imaging study","volume":"15","author":"Biegon","year":"1994","journal-title":"Neurobiol. Aging"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0006-8993(92)90178-C","article-title":"Fiber composition of the human corpus callosum","volume":"598","author":"Aboitiz","year":"1992","journal-title":"Brain Res."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1212\/WNL.0000000000002570","article-title":"Better verbal memory in women than men in MCI despite similar levels of hippocampal atrophy","volume":"86","author":"Sundermann","year":"2016","journal-title":"Neurology"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1523\/JNEUROSCI.21-01-00194.2001","article-title":"Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood","volume":"21","author":"Pruessner","year":"2001","journal-title":"J. Neurosci."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1097\/WNR.0b013e32832c5e65","article-title":"Sex differences in brain structure in auditory and cingulate regions","volume":"20","author":"Brun","year":"2009","journal-title":"Neuroreport"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1006\/nimg.2001.0857","article-title":"Cerebral asymmetry and the effects of sex and handedness on brain structure: A voxel-based morphometric analysis of 465 normal adult human brains","volume":"14","author":"Good","year":"2001","journal-title":"Neuroimage"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.optom.2014.12.005","article-title":"The King-Devick test for sideline concussion screening in collegiate football","volume":"8","author":"Leong","year":"2015","journal-title":"J. Optom."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Mainland, B.J., and Shulman, K.I. (2013). Clock Drawing Test. Cognitive Screening Instruments: A Practical Approach, Springer.","DOI":"10.1007\/978-1-4471-2452-8_5"},{"key":"ref_100","first-page":"59","article-title":"Age, gender, and impaired clock drawing in the generalist primary care setting","volume":"105","author":"Miles","year":"2007","journal-title":"J. Ky. Med. Assoc."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/gps.384","article-title":"Cognitive function in UK community-dwelling African Caribbean elders: Normative data for a test battery","volume":"16","author":"Stewart","year":"2001","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/13803390701346113","article-title":"Do age and education contribute to performance on the clock drawing test? Normative data for the Greek population","volume":"30","author":"Bozikas","year":"2008","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.expneurol.2017.11.001","article-title":"Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury","volume":"300","author":"Jaye","year":"2018","journal-title":"Exp. Neurol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"17018","DOI":"10.1038\/nrdp.2017.18","article-title":"Traumatic spinal cord injury","volume":"3","author":"Ahuja","year":"2017","journal-title":"Nat. Rev. Dis. Prim."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.pmrj.2017.01.005","article-title":"Characterization of Neck Strength in Healthy Young Adults","volume":"9","author":"Catenaccio","year":"2017","journal-title":"PM&R"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10935-014-0355-2","article-title":"Neck strength: A protective factor reducing risk for concussion in high school sports","volume":"35","author":"Collins","year":"2014","journal-title":"J. Prim. Prev."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1519\/JSC.0b013e31828a1fe2","article-title":"Collegiate and high school athlete neck strength in neutral and rotated postures","volume":"27","author":"Hildenbrand","year":"2013","journal-title":"J. Strength Cond. Res."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"495","DOI":"10.2519\/jospt.2006.2122","article-title":"Isometric strength of the cervical flexor, extensor, and rotator muscles in 220 healthy females aged 20 to 59 years","volume":"36","author":"Salo","year":"2006","journal-title":"J. Orthop. Sport Phys. Ther."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.apmr.2007.06.776","article-title":"Differences in isometric neck muscle strength between healthy controls and women with chronic neck pain: The use of a reliable measurement","volume":"88","author":"Cagnie","year":"2007","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"874","DOI":"10.2519\/jospt.2016.7049","article-title":"Whiplash Injury or Concussion? A Possible Biomechanical Explanation for Concussion Symptoms in Some Individuals Following a Rear-End Collision","volume":"46","author":"Elkin","year":"2016","journal-title":"J. Orthop. Sport Phys. Ther."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/02699050500443707","article-title":"Is there a relationship between whiplash-associated disorders and concussion in hockey? A preliminary study","volume":"20","author":"Hynes","year":"2006","journal-title":"Brain Inj."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0001-4575(02)00110-0","article-title":"Neck strains and sprains among motor vehicle occupants-United States, 2000","volume":"36","author":"Quinlan","year":"2004","journal-title":"Accid Anal. Prev."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"834","DOI":"10.2519\/jospt.2016.6846","article-title":"Whiplash-Associated Disorders: Occupant Kinematics and Neck Morphology","volume":"46","author":"Stemper","year":"2016","journal-title":"J. Orthop. Sport Phys. Ther."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"334","DOI":"10.2519\/jospt.2009.2765","article-title":"Risk factors for persistent problems following whiplash injury: Results of a systematic review and meta-analysis","volume":"39","author":"Walton","year":"2009","journal-title":"J. Orthop. Sport Phys. Ther."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1089\/jwh.2018.7282","article-title":"Neck Injury Comorbidity in Concussion-Related Emergency Department Visits: A Population-Based Study of Sex Differences Across the Life Span","volume":"28","author":"Sutton","year":"2019","journal-title":"J. Womens Health"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1097\/TA.0b013e31823f5e8e","article-title":"Epidemiology and predictors of cervical spine injury in adult major trauma patients: A multicenter cohort study","volume":"72","author":"Hasler","year":"2012","journal-title":"J. Trauma Acute Care Surg."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"252","DOI":"10.4103\/0974-2700.120365","article-title":"Risk factors for cervical spine injury among patients with traumatic brain injury","volume":"6","author":"Fujii","year":"2013","journal-title":"J. Emerg. Trauma Shock"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/nn.2834","article-title":"Reframing sexual differentiation of the brain","volume":"14","author":"McCarthy","year":"2011","journal-title":"Nat. Neurosci."},{"key":"ref_119","unstructured":"Tanopolsky, M.R.N.C. (1999). Gender Differences in Metabolism, Routledge."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s12031-018-1038-x","article-title":"Endogenous Sex Steroids Dampen Neuroinflammation and Improve Outcome of Traumatic Brain Injury in Mice","volume":"64","author":"Clevenger","year":"2018","journal-title":"J. Mol. Neurosci."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/neu.2018.6349","article-title":"Prevalence of Anterior Pituitary Dysfunction Twelve Months or More following Traumatic Brain Injury in Adults: A Systematic Review and Meta-Analysis","volume":"37","author":"Emelifeonwu","year":"2020","journal-title":"J. Neurotrauma"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"32987","DOI":"10.1038\/srep32987","article-title":"Endocrine dysfunction following traumatic brain injury: A 5-year follow-up nationwide-based study","volume":"6","author":"Yang","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1056\/NEJMoa1411090","article-title":"A clinical trial of progesterone for severe traumatic brain injury","volume":"371","author":"Skolnick","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/nn922","article-title":"Sex chromosome genes directly affect brain sexual differentiation","volume":"5","author":"Carruth","year":"2002","journal-title":"Nat. Neurosci."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/190372a0","article-title":"Gene action in the X-chromosome of the mouse (Mus musculus L.)","volume":"190","author":"Lyon","year":"1961","journal-title":"Nature"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00439-011-1011-z","article-title":"Genes that escape from X inactivation","volume":"130","author":"Berletch","year":"2011","journal-title":"Hum. Genet."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s10577-009-9063-9","article-title":"Dosage compensation and gene expression on the mammalian X chromosome: One plus one does not always equal two","volume":"17","author":"Prothero","year":"2009","journal-title":"Chromosome Res."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.brainres.2006.08.049","article-title":"Sex differences in brain expression of X- and Y-linked genes","volume":"1126","author":"Xu","year":"2006","journal-title":"Brain Res."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1093\/cercor\/bhs222","article-title":"Sex differences in the human brain and the impact of sex chromosomes and sex hormones","volume":"23","author":"Lentini","year":"2013","journal-title":"Cereb. Cortex"},{"key":"ref_130","first-page":"420","article-title":"Influence of sex and stress exposure across the lifespan on endophenotypes of depression: Focus on behavior, glucocorticoids, and hippocampus","volume":"8","author":"Gobinath","year":"2014","journal-title":"Front. Neurosci."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"76","DOI":"10.4085\/1062-6050-46.1.76","article-title":"Sex differences in concussion symptoms of high school athletes","volume":"46","author":"Frommer","year":"2011","journal-title":"J. Athl. Train."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.neuron.2008.10.010","article-title":"Mitochondria in neuroplasticity and neurological disorders","volume":"60","author":"Mattson","year":"2008","journal-title":"Neuron"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.2174\/138161211798357737","article-title":"Unmasking sex-based disparity in neuronal metabolism","volume":"17","author":"Manole","year":"2011","journal-title":"Curr. Pharm. Des."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.1210\/en.2007-1227","article-title":"Progesterone and estrogen regulate oxidative metabolism in brain mitochondria","volume":"149","author":"Irwin","year":"2008","journal-title":"Endocrinology"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0735-6757(99)90188-2","article-title":"Emergency department presentation of idiopathic intracranial hypertension","volume":"17","author":"Jones","year":"1999","journal-title":"Am. J. Emerg. Med."},{"key":"ref_136","first-page":"89","article-title":"Idiopathic intracranial hypertension: Mechanisms of visual loss and disease management","volume":"20","author":"Wall","year":"2000","journal-title":"Semin. Neurol."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1046\/j.1468-2982.2000.00034.x","article-title":"Physiology of the menstrual cycle","volume":"20","author":"Silberstein","year":"2000","journal-title":"Cephalalgia"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s12028-012-9780-3","article-title":"Intracranial pressure dose and outcome in traumatic brain injury","volume":"18","author":"Sheth","year":"2013","journal-title":"Neurocrit. Care"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1089\/neu.2014.3675","article-title":"Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury","volume":"32","author":"Yao","year":"2015","journal-title":"J. Neurotrauma"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neulet.2015.05.006","article-title":"Deletion of aquaporin-4 is neuroprotective during the acute stage of micro traumatic brain injury in mice","volume":"598","author":"Liang","year":"2015","journal-title":"Neurosci. Lett."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"576366","DOI":"10.3389\/fneur.2021.576366","article-title":"Considering biological sex in traumatic brain injury","volume":"12","author":"Biegon","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_142","first-page":"28","article-title":"A review of head injury and finite element head models","volume":"1","author":"Tse","year":"2014","journal-title":"Am. J. Eng. Technol. Soc."},{"key":"ref_143","unstructured":"Carlsson, A., Chang, F., Lemmen, P., Kullgren, A., Schmitt, K.U., Linder, A., and Svensson, M. (2012, January 12\u201314). EvaRID\u2014A 50th Percentile Female Rear Impact Finite Element Dummy Model. Proceedings of the 2012 IRCOBI Conference, Dublin, Ireland."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.2105\/AJPH.2011.300275","article-title":"Vulnerability of female drivers involved in motor vehicle crashes: An analysis of US population at risk","volume":"101","author":"Bose","year":"2011","journal-title":"Am. J. Public Health"},{"key":"ref_145","unstructured":"Abrams, M.Z., and Bass, C.R. (2020, January 11\u201314). Female vs. Male relative fatality risk in fatal crashes. Proceedings of the 2020 IRCOBI Conference, Beijing, China."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0377-0427(00)00507-0","article-title":"From finite differences to finite elements: A short history of numerical analysis of partial differential equations","volume":"128","year":"2001","journal-title":"J. Comput. Appl. Math."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1115\/1.3423172","article-title":"Elastic Analysis of a Skull","volume":"40","author":"Hardy","year":"1973","journal-title":"J. Appl. Mech."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1115\/1.3438355","article-title":"In-Vacuo Modal Dynamic Response of the Human Skull","volume":"96","author":"Nickell","year":"1974","journal-title":"J. Eng. Ind."},{"key":"ref_149","first-page":"123","article-title":"Two-dimensional finite element analysis of human Brain Impact Responses: Application of a Scaling Law","volume":"106","author":"Ueno","year":"1989","journal-title":"Crashworthiness Occupant Prot. Transp. Syst."},{"key":"ref_150","first-page":"121","article-title":"Two-dimentional finite element model of the cortical impact method for mechanical brain injury. Crash-worthiness and Occupant Protection in Transportation System","volume":"19","author":"Ueno","year":"1991","journal-title":"SAME"},{"key":"ref_151","doi-asserted-by":"crossref","unstructured":"McGill, K., Teixeira-Dias, F., and Callanan, A. (2020). A Review of Validation Methods for the Intracranial Response of FEHM to Blunt Impacts. Appl. Sci., 10.","DOI":"10.3390\/app10207227"},{"key":"ref_152","first-page":"2638","article-title":"Experimental model for closed head impact injury","volume":"85","author":"Nahum","year":"1976","journal-title":"SAE Trans."},{"key":"ref_153","doi-asserted-by":"crossref","unstructured":"Nahum, A.M., Smith, R., and Ward, C.C. (1977). Intracranial Pressure Dynamics during Head Impact, SAE. SAE Technical Paper 770922.","DOI":"10.4271\/770922"},{"key":"ref_154","doi-asserted-by":"crossref","unstructured":"Trosseille, X., Tarriere, C., Lavaste, F., Guillon, F., and Domont, A. (1992). Development of a FEM of the Human Head according to a Specific Test Protocol, SAE. SAE Technical Paper 922527.","DOI":"10.4271\/922527"},{"key":"ref_155","doi-asserted-by":"crossref","unstructured":"Hardy, W.N., Foster, C.D., Mason, M.J., Yang, K.H., King, A.I., and Tashman, S. (2001). Investigation of Head Injury Mechanisms Using Neutral Density Technology and High-Speed Biplanar X-ray, SAE. SAE Technical Report.","DOI":"10.4271\/2001-22-0016"},{"key":"ref_156","first-page":"17","article-title":"A study of the response of the human cadaver head to impact","volume":"51","author":"Hardy","year":"2007","journal-title":"Stapp Car Crash J."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1089\/neu.2017.5362","article-title":"A Novel Method for Quantifying Human In Situ Whole Brain Deformation under Rotational Loading Using Sonomicrometry","volume":"35","author":"Alshareef","year":"2018","journal-title":"J. Neurotrauma"},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1089\/neu.2019.6847","article-title":"Biomechanics of the Human Brain during Dynamic Rotation of the Head","volume":"37","author":"Alshareef","year":"2020","journal-title":"J. Neurotrauma"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1007\/s10439-019-02239-8","article-title":"Explicit modeling of white matter axonal fiber tracts in a finite element brain model","volume":"47","author":"Wu","year":"2019","journal-title":"Ann. Biomed. Eng."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"309","DOI":"10.3389\/fbioe.2020.00309","article-title":"Predicting Concussion Outcome by Integrating Finite Element Modeling and Network Analysis","volume":"8","author":"Anderson","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0020-7403(72)90056-2","article-title":"Dynamic loading of a fluid-filled spherical shell","volume":"14","author":"Kenner","year":"1972","journal-title":"Int. J. Mech. Sci."},{"key":"ref_162","first-page":"3814","article-title":"Mathematical model for closed head impact","volume":"83","author":"Chan","year":"1974","journal-title":"SAE Trans."},{"key":"ref_163","first-page":"581","article-title":"Transient structural response of the linear skull-brain system","volume":"19","author":"Shugar","year":"1975","journal-title":"Proc. Stapp Car Crash Conf."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1061\/JMCEA3.0002012","article-title":"Development of finite element head injury model","volume":"101","author":"Shugar","year":"1975","journal-title":"J. Eng. Mech. Div."},{"key":"ref_165","first-page":"3238","article-title":"The development of a detailed finite element brain model","volume":"84","author":"Ward","year":"1975","journal-title":"SAE Trans."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0021-9290(77)90075-6","article-title":"Parametric study of head response by finite element modeling","volume":"10","author":"Khalil","year":"1977","journal-title":"J. Biomech."},{"key":"ref_167","doi-asserted-by":"crossref","unstructured":"Hosey, R. (1982). A Homeomorphic Finite Element Model of the Human Head and Neck. Finite Elements in Biomechanics, Wiley.","DOI":"10.1016\/0021-9290(83)90164-1"},{"key":"ref_168","doi-asserted-by":"crossref","unstructured":"Ruan, J.S., Khalil, T.B., and King, A.I. (1993). Finite Element Modeling of Direct Head Impact, SAE. SAE Technical Report.","DOI":"10.4271\/933114"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1115\/1.2895703","article-title":"Dynamic Response of the Human Head to Impact by Three-Dimensional Finite Element Analysis","volume":"116","author":"Ruan","year":"1994","journal-title":"J. Biomech. Eng."},{"key":"ref_170","first-page":"2999","article-title":"A new model comparing impact responses of the homogeneous and inhomogeneous human brain","volume":"104","author":"Zhou","year":"1995","journal-title":"SAE Trans."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02637019","article-title":"Importance of partitioning membranes of the brain and the influence of the neck in head injury modelling","volume":"34","author":"Kumaresan","year":"1996","journal-title":"Med Biol. Eng. Comput."},{"key":"ref_172","first-page":"3849","article-title":"Validation of a 3D Anatomic Human Head Model and Replication of Head Impact in Motorcycle Accident by Finite Element Modeling","volume":"106","author":"Kang","year":"1997","journal-title":"SAE Trans."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1114\/1.165","article-title":"Three-dimensional human head finite-element model validation against two experimental impacts","volume":"27","author":"Willinger","year":"1999","journal-title":"Ann. Biomed. Eng."},{"key":"ref_174","first-page":"375","article-title":"Recent advances in brain injury research: A new human head model development and validation","volume":"45","author":"Zhang","year":"2001","journal-title":"Stapp Car Crash J."},{"key":"ref_175","first-page":"123","article-title":"Correlation of an FE Model of the Human Head with Local Brain Motion\u2013Consequences for Injury Prediction","volume":"46","author":"Kleiven","year":"2002","journal-title":"Stapp Car Crash J."},{"key":"ref_176","unstructured":"King, A.I., Yang, K.H., Zhang, L., Hardy, W., and Viano, D.C. (2003, January 25\u201326). Is head injury caused by linear or angular acceleration. Proceedings of the IRCOBI Conference, Lisbon, Portugal."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1533\/ijcr.2003.0243","article-title":"The creation of three-dimensional finite element models for simulating head impact biomechanics","volume":"8","author":"Horgan","year":"2003","journal-title":"Int. J. Crashworthiness"},{"key":"ref_178","doi-asserted-by":"crossref","unstructured":"Takhounts, E.G., Eppinger, R.H., Campbell, J.Q., Tannous, R.E., Power, E.D., and Shook, L.S. (2003). On the Development of the SIMon Finite Element Head Model, SAE. SAE Technical Report.","DOI":"10.4271\/2003-22-0007"},{"key":"ref_179","doi-asserted-by":"crossref","unstructured":"Takhounts, E.G., Ridella, S.A., Hasija, V., Tannous, R.E., Campbell, J.Q., Malone, D., Danelson, K., Stitzel, J., Rowson, S., and Duma, S. (2008). Investigation of Traumatic Brain Injuries Using the Next Generation of Simulated Injury Monitor (SIMon) Finite Element Head Model, SAE. SAE Technical Report.","DOI":"10.4271\/2008-22-0001"},{"key":"ref_180","unstructured":"Belingardi, G., Chiandussi, G., and Gaviglio, I. (2005, January 6\u20139). Development and validation of a new finite element model of human head. Proceedings of the 19th International Technical Conference of the Enhanced Safety of Vehicle (ESV), Washington, DC, USA."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jbiomech.2004.11.015","article-title":"A three-dimensional human head finite element model and power flow in a human head subject to impact loading","volume":"39","author":"Zong","year":"2006","journal-title":"J. Biomech."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10439-011-0402-6","article-title":"Maximum Principal Strain and Strain Rate Associated with Concussion Diagnosis Correlates with Changes in Corpus Callosum White Matter Indices","volume":"40","author":"McAllister","year":"2012","journal-title":"Ann. Biomed. Eng."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"4025101","DOI":"10.1115\/1.4025101","article-title":"Development of a Finite Element Human Head Model Partially Validated With Thirty Five Experimental Cases","volume":"135","author":"Mao","year":"2013","journal-title":"J. Biomech. Eng."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"408278","DOI":"10.1155\/2014\/408278","article-title":"Development of a finite element head model for the study of impact head injury","volume":"2014","author":"Yang","year":"2014","journal-title":"BioMed Res. Int."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jmbbm.2013.08.022","article-title":"Development and validation of an advanced anisotropic visco-hyperelastic human brain FE model","volume":"33","author":"Sahoo","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1089\/neu.2013.3268","article-title":"Group-Wise Evaluation and Comparison of White Matter Fiber Strain and Maximum Principal Strain in Sports-Related Concussion","volume":"32","author":"Ji","year":"2015","journal-title":"J. Neurotrauma"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s10237-014-0634-0","article-title":"Brain pressure responses in translational head impact: A dimensional analysis and a further computational study","volume":"14","author":"Zhao","year":"2015","journal-title":"Biomech. Model. Mechanobiol."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1504\/IJVS.2016.077145","article-title":"Development and validation of a head\/brain FE model and investigation of influential factor on the brain response during head impact","volume":"9","author":"Atsumi","year":"2016","journal-title":"Int. J. Veh. Saf."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s10237-015-0754-1","article-title":"Development and validation of an atlas-based finite element brain model","volume":"15","author":"Miller","year":"2016","journal-title":"Biomech. Model. Mechanobiol."},{"key":"ref_190","unstructured":"Miyazaki, Y., Railkar, A., Awamori, S., Kokeguchi, A., Amamori, I., Katagiri, M., and Yoshii, K. (2017, January 13\u201315). Intracranial Brain Motion Measurement in Frontal Sled Tests by Using a New Anthropometric Test Dummy Head Capable of Direct Brain Motion Evaluation and Visualisation. Proceedings of the IRCOBI Conference, Antwerp, Belgium."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1080\/02699052.2018.1502470","article-title":"Fluid\u2013structure interaction analysis of cerebrospinal fluid with a comprehensive head model subject to a rapid acceleration and deceleration","volume":"32","author":"Toma","year":"2018","journal-title":"Brain Inj."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/13588265.2018.1550910","article-title":"Coup-contrecoup brain injury: Fluid\u2013structure interaction simulations","volume":"25","author":"Toma","year":"2020","journal-title":"Int. J. Crashworthiness"},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1055\/s-0040-1708495","article-title":"Cerebrospinal fluid interaction with cerebral cortex during pediatric abusive head trauma","volume":"18","author":"Toma","year":"2020","journal-title":"J. Pediatr. Neurol."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1108\/EC-09-2016-0321","article-title":"Development and validation of a new finite element human head model: Yet another head model (YEAHM)","volume":"35","author":"Fernandes","year":"2018","journal-title":"Eng. Comput."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.clinbiomech.2019.02.010","article-title":"Detection of bridging veins rupture and subdural haematoma onset using a finite element head model","volume":"63","author":"Migueis","year":"2019","journal-title":"Clin. Biomech."},{"key":"ref_196","doi-asserted-by":"crossref","unstructured":"Barbosa, A., Fernandes, F.A.O., Alves de Sousa, R.J., Ptak, M., and Wilhelm, J. (2020). Computational Modeling of Skull Bone Structures and Simulation of Skull Fractures Using the YEAHM Head Model. Biology, 9.","DOI":"10.3390\/biology9090267"},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"103976","DOI":"10.1016\/j.jmbbm.2020.103976","article-title":"Prediction of subdural haematoma based on a detailed numerical model of the cerebral bridging veins","volume":"111","author":"Costa","year":"2020","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_198","doi-asserted-by":"crossref","unstructured":"Huang, J., Raymond, D., Shen, W., Stuhmiller, J., Crawford, G., and Bir, C. (2011, January 11\u201317). Development and Validation of a Subject-Specific Finite Element Model for Skull Fracture Assessment. Proceedings of the ASME International Mechanical Engineering Congress and Exposition, Denver, CO, USA.","DOI":"10.1115\/IMECE2011-63682"},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3171\/jns.2006.104.6.950","article-title":"Mechanics of acute subdural hematomas resulting from bridging vein rupture","volume":"104","author":"Depreitere","year":"2006","journal-title":"J. Neurosurg. JNS"},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0954411919881526","article-title":"Intracranial pressure\u2013based validation and analysis of traumatic brain injury using a new three-dimensional finite element human head model","volume":"234","author":"Khanuja","year":"2020","journal-title":"Proc. Inst. Mech. Eng. Part H J. Eng. Med."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.15282\/jmes.14.2.2020.01.0513","article-title":"A simplified human head finite element model for brain injury assessment of blunt impacts","volume":"14","author":"Hassan","year":"2020","journal-title":"J. Mech. Eng. Sci."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"105448","DOI":"10.1016\/j.ijmecsci.2020.105448","article-title":"Biofidelic finite element modelling of brain trauma: Importance of the scalp in simulating head impact","volume":"173","author":"Trotta","year":"2020","journal-title":"Int. J. Mech. Sci."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10237-020-01391-8","article-title":"An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain","volume":"20","author":"Li","year":"2021","journal-title":"Biomech. Model. Mechanobiol."},{"key":"ref_204","doi-asserted-by":"crossref","unstructured":"Pastakia, K., and Kumar, S. (2011). Acute Whiplash Associated Disorders (WAD). [Ph.D. Thesis, University of South Australia].","DOI":"10.2147\/OAEM.S17853"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jbiomech.2007.07.007","article-title":"Head and neck anthropometry, vertebral geometry and neck strength in height-matched men and women","volume":"41","author":"Vasavada","year":"2008","journal-title":"J. Biomech."},{"key":"ref_206","first-page":"149","article-title":"Gender dependent cervical spine anatomical differences in size-matched volunteers","volume":"45","author":"Stemper","year":"2009","journal-title":"Biomed. Sci. Instrum."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.clinbiomech.2006.07.002","article-title":"Influence of gender, estrogen and exercise on anterior knee laxity","volume":"21","author":"Pollard","year":"2006","journal-title":"Clin. Biomech."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jsams.2007.05.005","article-title":"The effects of gender and pubertal status on generalized joint laxity in young athletes","volume":"11","author":"Quatman","year":"2008","journal-title":"J. Sci. Med. Sport"},{"key":"ref_209","first-page":"594","article-title":"Sex differences in knee joint laxity change across the female menstrual cycle","volume":"45","author":"Shultz","year":"2005","journal-title":"J. Sport. Med. Phys. Fit."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.cegh.2019.10.009","article-title":"Epidemiology of generalized ligamentous laxity in northwest of Iran: A pilot national study on 17\u201340 years old adults in Hamadan province","volume":"8","author":"Saremi","year":"2020","journal-title":"Clin. Epidemiol. Glob. Health"},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.jbiomech.2012.12.018","article-title":"Sex-specific prediction of neck muscle volumes","volume":"46","author":"Zheng","year":"2013","journal-title":"J. Biomech."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"110660","DOI":"10.1016\/j.jbiomech.2021.110660","article-title":"Sex and posture dependence of neck muscle size-strength relationships","volume":"127","author":"Reddy","year":"2021","journal-title":"J. Biomech."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"102590","DOI":"10.1016\/j.msksp.2022.102590","article-title":"Sex-related differences in sternocleidomastoid muscle morphology in healthy young adults: A cross-sectional magnetic resonance imaging measurement study","volume":"61","author":"Migotto","year":"2022","journal-title":"Musculoskelet. Sci. Pract."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1097\/00007632-199105000-00002","article-title":"Analysis and prevention of spinal column deformity following cervical laminectomy. I. Pathogenetic analysis of postlaminectomy deformities","volume":"16","author":"Saito","year":"1991","journal-title":"Spine"},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0021-9290(97)00056-0","article-title":"A three-dimensional parameterized finite element model of the lower cervical spine, study of the influence of the posterior articular facets","volume":"30","author":"Maurel","year":"1997","journal-title":"J. Biomech."},{"key":"ref_216","unstructured":"Moroney, S.P. (1984). Mechanical Properties and Muscle Force Analyses of the Lower Cervical Spine (Stiffness, Modelling, Motion Segment). [Ph.D. Thesis, University of Illinois]."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0021-9290(88)90285-0","article-title":"Load-displacement properties of lower cervical spine motion segments","volume":"21","author":"Moroney","year":"1988","journal-title":"J. Biomech."},{"key":"ref_218","first-page":"117","article-title":"Cervical spine stabilization. A three-dimensional, biomechanical evaluation of rotational stability, strength, and failure mechanisms","volume":"16","author":"Pelker","year":"1991","journal-title":"Spine"},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jbiomech.2004.10.029","article-title":"Finite element analysis of moment-rotation relationships for human cervical spine","volume":"39","author":"Zhang","year":"2006","journal-title":"J. Biomech."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s005860050112","article-title":"Whiplash injuries and the potential for mechanical instability","volume":"7","author":"Panjabi","year":"1998","journal-title":"Eur. Spine J."},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1097\/00007632-200112150-00012","article-title":"Mechanical properties of the human cervical spine as shown by three-dimensional load\u2013displacement curves","volume":"26","author":"Panjabi","year":"2001","journal-title":"Spine"},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.cmpb.2009.03.005","article-title":"An interactive multiblock approach to meshing the spine","volume":"95","author":"Kallemeyn","year":"2009","journal-title":"Comput. Methods Programs Biomed."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.medengphy.2010.03.001","article-title":"Validation of a C2\u2013C7 cervical spine finite element model using specimen-specific flexibility data","volume":"32","author":"Kallemeyn","year":"2010","journal-title":"Med. Eng. Phys."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3171\/jns.1993.79.1.0096","article-title":"Biomechanical comparison of anterior Caspar plate and three-level posterior fixation techniques in a human cadaveric model","volume":"79","author":"Traynelis","year":"1993","journal-title":"J. Neurosurg."},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.medengphy.2011.05.004","article-title":"Cervical spine response in frontal crash","volume":"33","author":"Panzer","year":"2011","journal-title":"Med. Eng. Phys."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jbiomech.2004.11.014","article-title":"Experimental flexion\/extension data corridors for validation of finite element models of the young, normal cervical spine","volume":"39","author":"Wheeldon","year":"2006","journal-title":"J. Biomech."},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0021-9290(02)00037-4","article-title":"Comparative strengths and structural properties of the upper and lower cervical spine in flexion and extension","volume":"35","author":"Nightingale","year":"2002","journal-title":"J. Biomech."},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jbiomech.2006.02.015","article-title":"Flexion and extension structural properties and strengths for male cervical spine segments","volume":"40","author":"Nightingale","year":"2007","journal-title":"J. Biomech."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"3127257","DOI":"10.1115\/1.3127257","article-title":"Tension and Combined Tension-Extension Structural Response and Tolerance Properties of the Human Male Ligamentous Cervical Spine","volume":"131","author":"Dibb","year":"2009","journal-title":"J. Biomech. Eng."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.scient.2011.10.002","article-title":"Generating a finite element model of the cervical spine: Estimating muscle forces and internal loads","volume":"18","author":"Toosizadeh","year":"2011","journal-title":"Sci. Iran"},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.medengphy.2014.02.020","article-title":"Application of an asymmetric finite element model of the C2-T1 cervical spine for evaluating the role of soft tissues in stability","volume":"36","author":"Erbulut","year":"2014","journal-title":"Med. Eng. Phys."},{"key":"ref_232","first-page":"4032966","article-title":"A Female Ligamentous Cervical Spine Finite Element Model Validated for Physiological Loads","volume":"138","author":"Brolin","year":"2016","journal-title":"J. Biomech. Eng."},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jbiomech.2016.11.066","article-title":"A female head\u2013neck model for rear impact simulations","volume":"51","author":"Sato","year":"2017","journal-title":"J. Biomech."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/jor.1100040203","article-title":"Three-dimensional load-displacement curves due to froces on the cervical spine","volume":"4","author":"Panjabi","year":"1986","journal-title":"J. Orthop. Res."},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0021-9290(03)00159-3","article-title":"Gender dependent cervical spine segmental kinematics during whiplash","volume":"36","author":"Stemper","year":"2003","journal-title":"J. Biomech."},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1097\/01.BRS.0000134563.10718.A7","article-title":"Gender-and region-dependent local facet joint kinematics in rear impact: Implications in whiplash injury","volume":"29","author":"Stemper","year":"2004","journal-title":"Spine"},{"key":"ref_237","first-page":"149","article-title":"Response corridors of the human head-neck complex in rear impact","volume":"48","author":"Stemper","year":"2004","journal-title":"Annu. Proc. Assoc. Adv. Automot. Med."},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"103519","DOI":"10.1016\/j.compbiomed.2019.103519","article-title":"Using finite element analysis to determine effects of the motion loading method on facet joint forces after cervical disc degeneration","volume":"116","author":"Cai","year":"2020","journal-title":"Comput. Biol. Med."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.2106\/JBJS.F.00200","article-title":"Level-dependent coronal and axial moment-rotation corridors of degeneration-free cervical spines in lateral flexion","volume":"89","author":"Yoganandan","year":"2007","journal-title":"JBJS"},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/BRS.0b013e3181657f67","article-title":"Normative segment-specific axial and coronal angulation corridors of subaxial cervical column in axial rotation","volume":"33","author":"Yoganandan","year":"2008","journal-title":"Spine"},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.neubiorev.2021.02.026","article-title":"Dump the \u201cdimorphism\u201d: Comprehensive synthesis of human brain studies reveals few male-female differences beyond size","volume":"125","author":"Eliot","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_242","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.neubiorev.2021.04.020","article-title":"Binary thinking about the sex binary: A comment on Joel (2021)","volume":"127","author":"Giudice","year":"2021","journal-title":"Neurosci. Biobehav. Rev."}],"container-title":["Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-7737\/12\/1\/83\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T17:58:32Z","timestamp":1760119112000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-7737\/12\/1\/83"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,4]]},"references-count":242,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["biology12010083"],"URL":"https:\/\/doi.org\/10.3390\/biology12010083","relation":{},"ISSN":["2079-7737"],"issn-type":[{"value":"2079-7737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,4]]}}}