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Several amines were used as nitrogen additives to enhance the fluorescence quantum yield (QY) of CDs, and a set of reaction conditions, including additive\/TW mass ratio (0.04\u20130.32), dwell time (15\u201360 min), and temperature (200\u2013230 \u00b0C) of the HTC process, were scrutinized. The structural analysis of the tomato waste carbon dots (TWCDs) was undertaken by FTIR and 1H NMR techniques, revealing their most relevant features. In solid state, transmission electron microscopy (TEM) analysis showed the presence of nearly spherical nanoparticles with an average lateral size of 8.1 nm. Likewise, the topographical assessment by atomic force microscopy (AFM) also indicated particles\u2019 heights between 3 and 10 nm. Their photophysical properties, revealed by UV\u2013Vis, steady-state, and time-resolved fluorescence spectroscopies, are fully discussed. Higher photoluminescent quantum yields (up to 0.08) were attained when the biomass residues were mixed with organic aliphatic amines during the Mw-HTC process. Emission tunability is a characteristic feature of these CDs, which display an intensity average fluorescence lifetime of 8 ns. The new TWCDs demonstrated good antioxidant properties by the ABTS radical cation method (75% inhibition at TWCDs\u2019 concentration of 5 mg\/mL), which proved to be related to the dwell time used in the CDs synthesis. Moreover, the synthesized TWCDs suppressed the growth of Escherichia coli and Staphylococcus aureus at concentrations higher than 2000 \u03bcg\/mL, encouraging future antibacterial applications.<\/jats:p>","DOI":"10.3390\/biomass5020035","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T09:59:14Z","timestamp":1749549554000},"page":"35","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["One-Pot Microwave-Assisted Synthesis of Fluorescent Carbon Dots from Tomato Industry Residues with Antioxidant and Antibacterial Activities"],"prefix":"10.3390","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8274-633X","authenticated-orcid":false,"given":"Patr\u00edcia D.","family":"Barata","sequence":"first","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"},{"name":"Centro de Qu\u00edmica-Vila Real, Universidade de Tr\u00e1s-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5518-6506","authenticated-orcid":false,"given":"Alexandra I.","family":"Costa","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"},{"name":"Centro de Qu\u00edmica-Vila Real, Universidade de Tr\u00e1s-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1874-0192","authenticated-orcid":false,"given":"S\u00f3nia","family":"Martins","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"},{"name":"Centro de Geobioci\u00eancias, Geoengenharias e Geotecnologias (GeoBioTec), FCT-UNL, Monte de Caparica, 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6330-2899","authenticated-orcid":false,"given":"Magda C.","family":"Semedo","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"},{"name":"Centro de Geobioci\u00eancias, Geoengenharias e Geotecnologias (GeoBioTec), FCT-UNL, Monte de Caparica, 2829-516 Caparica, Portugal"}]},{"given":"Bruno G.","family":"Antunes","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9068-2847","authenticated-orcid":false,"given":"Jos\u00e9 V.","family":"Prata","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia Qu\u00edmica, Instituto Superior de Engenharia de Lisboa, Instituto Polit\u00e9cnico de Lisboa, R. Conselheiro Em\u00eddio Navarro, 1, 1959-007 Lisboa, Portugal"},{"name":"Centro de Qu\u00edmica-Vila Real, Universidade de Tr\u00e1s-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"ref_1","unstructured":"(2025, May 01). Tomato Production by Country 2025. Available online: https:\/\/worldpopulationreview.com\/country-rankings\/tomato-production-by-country."},{"key":"ref_2","unstructured":"Food and Agriculture Organization of the United Nations (2023). 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